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Intensive care units (ICU) generate long, dense and evolving streams of clinical information, where physicians must repeatedly reassess patient states under time pressure, underscoring a clear need for reliable AI decision support. Existing…

Artificial Intelligence · Computer Science 2026-05-14 Chengzhi Shen , Weixiang Shen , Tobias Susetzky , Chen , Chen , Jun Li , Yuyuan Liu , Xuepeng Zhang , Zhenyu Gong , Daniel Rueckert , Jiazhen Pan

The recent release of large-scale healthcare datasets has greatly propelled the research of data-driven deep learning models for healthcare applications. However, due to the nature of such deep black-boxed models, concerns about…

Machine Learning · Computer Science 2021-02-16 Chuizheng Meng , Loc Trinh , Nan Xu , Yan Liu

Alarm fatigue in intensive care units (ICUs) is a well documented patient safety crisis. Clinical monitors generate 350 or more alarms per patient per day, out of which 72-99% are clinically irrelevant. Staff desensitization to…

Machine Learning · Computer Science 2026-05-29 Arunkumar Ramachandran

Sepsis is an organ dysfunction caused by a deregulated immune response to an infection. Early sepsis prediction and identification allow for timely intervention, leading to improved clinical outcomes. Clinical calculators (e.g., the…

Machine Learning · Computer Science 2025-01-13 Changchang Yin , Shihan Fu , Bingsheng Yao , Thai-Hoang Pham , Weidan Cao , Dakuo Wang , Jeffrey Caterino , Ping Zhang

This paper introduces an innovative framework designed for progressive (granular in time to onset) prediction of seizures through the utilization of a Deep Learning (DL) methodology based on non-invasive multi-modal sensor networks.…

Signal Processing · Electrical Eng. & Systems 2024-11-05 Ali Saeizadeh , Douglas Schonholtz , Joseph S. Neimat , Pedram Johari , Tommaso Melodia

Accurate Intensive Care Unit (ICU) outcome prediction is critical for improving patient treatment quality and ICU resource allocation. Existing research mainly focuses on structured data, e.g. demographics and vital signs, and lacks…

Information Theory · Computer Science 2025-02-26 Yucheng Ruan , Daniel J. Tan , See Kiong Ng , Ling Huang , Mengling Feng

Current research efforts largely focus on employing at most one interpretable method to elucidate machine learning (ML) model performance. However, significant barriers remain in translating these interpretability techniques into actionable…

Computers and Society · Computer Science 2025-08-05 Ling Liao , Eva Aagaard

Clinical practice in intensive care units (ICUs) requires early warnings when a patient's condition is about to deteriorate so that preventive measures can be undertaken. To this end, prediction algorithms have been developed that estimate…

Machine Learning · Computer Science 2021-02-18 Yilmazcan Özyurt , Mathias Kraus , Tobias Hatt , Stefan Feuerriegel

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Patients with chronic obstructive pulmonary disease (COPD) have an increased risk of hospitalizations, strongly associated with decreased survival, yet predicting the timing of these events remains challenging and has received limited…

Artificial intelligence (AI) systems can detect disease-related acoustic patterns in cough sounds, offering a scalable and cost-effective approach to tuberculosis (TB) screening in high-burden, resource-limited settings. Previous studies…

Sepsis remains one of the leading causes of mortality in intensive care units, where timely and accurate treatment decisions can significantly impact patient outcomes. In this work, we propose an interpretable decision support framework.…

Machine Learning · Computer Science 2026-01-21 Punit Kumar , Vaibhav Saran , Divyesh Patel , Nitin Kulkarni , Alina Vereshchaka

Sepsis is the leading cause of death in non-coronary intensive care units. Moreover, a delay of antibiotic treatment of patients with severe sepsis by only few hours is associated with increased mortality. This insight makes accurate models…

Quantitative Methods · Quantitative Biology 2019-09-26 Shigehiko Schamoni , Holger A. Lindner , Verena Schneider-Lindner , Manfred Thiel , Stefan Riezler

Sepsis is a life threatening condition that requires timely detection in intensive care settings. Traditional machine learning approaches, including Naive Bayes, Support Vector Machine (SVM), Random Forest, and XGBoost, often rely on manual…

Machine Learning · Computer Science 2025-09-03 Hejiang Cai , Di Wu , Ji Xu , Xiang Liu , Yiziting Zhu , Xin Shu , Yujie Li , Bin Yi

Artificial intelligence-based analysis of lung ultrasound imaging has been demonstrated as an effective technique for rapid diagnostic decision support throughout the COVID-19 pandemic. However, such techniques can require days- or…

Consider a situation where a new patient arrives in the Intensive Care Unit (ICU) and is monitored by multiple sensors. We wish to assess relevant unmeasured physiological variables (e.g., cardiac contractility and output and vascular…

Machine Learning · Statistics 2022-02-17 Ron Teichner , Ron Meir , Danny Eitan

Vital signs are crucial in intensive care units (ICUs). They are used to track the patient's state and to identify clinically significant changes. Predicting vital sign trajectories is valuable for early detection of adverse events.…

Machine Learning · Computer Science 2024-03-28 Bar Eini Porat , Danny Eytan , Uri Shalit

Preliminary detection of mild depression could immensely help in effective treatment of the common mental health disorder. Due to the lack of proper awareness and the ample mix of stigmas and misconceptions present within the society,…

Machine learning and deep learning methods have become essential for computer-assisted prediction in medicine, with a growing number of applications also in the field of mammography. Typically these algorithms are trained for a specific…

Image and Video Processing · Electrical Eng. & Systems 2021-12-03 Maria Wimmer , Gert Sluiter , David Major , Dimitrios Lenis , Astrid Berg , Theresa Neubauer , Katja Bühler

As more Intensive Care Unit (ICU) data becomes available, the interest in developing clinical prediction models to improve healthcare protocols increases. However, the lack of data quality still hinders clinical prediction using Machine…