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Swimming bacteria create long-range velocity fields that stir a large volume of fluid and move around passive particles dispersed in the fluid. Recent experiments and simulations have shown that long-time mean-squared displacement of…

Soft Condensed Matter · Physics 2013-08-20 Alexander Morozov , Davide Marenduzzo

In bacteria, regulatory proteins search for a specific DNA binding target via "facilitated diffusion": a series of rounds of 3D diffusion in the cytoplasm, and 1D linear diffusion along the DNA contour. Using large scale Brownian dynamics…

Biological Physics · Physics 2013-09-05 C. A. Brackley , M. E. Cates , D. Marenduzzo

We consider the diffusion and spreading of chainlike molecules on solid surfaces. We first show that the steep spherical cap shape density profiles, observed in some submonolayer experiments on spreading polymer films, imply that the…

Soft Condensed Matter · Physics 2009-10-31 T. Hjelt , S. Herminghaus , T. Ala-Nissila , S. C. Ying

Collective migration dominates many phenomena, from cell movement in living systems to abiotic self-propelling particles. Focusing on the early stages of tumor evolution, we enunciate the principles involved in cell dynamics and highlight…

Cell Behavior · Quantitative Biology 2018-05-02 Abdul N Malmi-Kakkada , Xin Li , Himadri S. Samanta , Sumit Sinha , D. Thirumalai

Understanding mixing and transport of passive scalars in active fluids is important to many natural (e.g. algal blooms) and industrial (e.g. biofuel, vaccine production) processes. Here, we study the mixing of a passive scalar (dye) in…

Bacterial processes ranging from gene expression to motility and biofilm formation are constantly challenged by internal and external noise. While the importance of stochastic fluctuations has been appreciated for chemotaxis, it is…

Biological Physics · Physics 2011-07-13 Knut Drescher , Jörn Dunkel , Luis H. Cisneros , Sujoy Ganguly , Raymond E. Goldstein

We study bidisperse colloidal suspensions confined within glass microcapillary tubes to model the glass transition in confined cylindrical geometries. We use high speed three-dimensional confocal microscopy to observe particle motions for a…

Soft Condensed Matter · Physics 2013-02-28 Nabiha Saklayen , Gary L. Hunter , Kazem V. Edmond , Eric R. Weeks

Diverse processes--e.g. bioremediation, biofertilization, and microbial drug delivery--rely on bacterial migration in disordered, three-dimensional (3D) porous media. However, how pore-scale confinement alters bacterial motility is unknown…

Soft Condensed Matter · Physics 2019-05-09 Tapomoy Bhattacharjee , Sujit S. Datta

The effect of crowding on the run-and-tumble dynamics of swimmers such as bacteria is studied using a discrete lattice model of mutually excluding particles that move with constant velocity along a direction that is randomized at a rate…

Soft Condensed Matter · Physics 2015-06-16 Rodrigo Soto , Ramin Golestanian

The role of activity on the hydrodynamic dispersion of bacteria in a model porous medium is studied by tracking thousands of bacteria in a microfluidic chip containing randomly placed pillars. We first evaluate the spreading dynamics of two…

Based on a coarse-grained model, we carry out molecular dynamics simulations to analyze the diffusion of a small tracer particle inside a cylindrical channel whose inner wall is covered with randomly grafted short polymeric chains. We…

Soft Condensed Matter · Physics 2013-06-20 Rajarshi Chakrabarti , Stefan Kesselheim , Peter Kosovan , Christian Holm

This fluid dynamics video presents three-dimensional kinetic simulations of the dynamics in suspensions of oxytactic bacteria confined in thin liquid film surrounded by air. At the initial time, the bacterial concentration is uniform and…

Fluid Dynamics · Physics 2011-10-17 Barath Ezhilan , Amir Alizadeh Pahlavan , David Saintillan

A biomimetic model of cell-cell communication was developed to probe the passive molecular transport across ion channels inserted in synthetic lipid bilayers formed between contacting droplets arranged in a linear array. Diffusion of a…

Biological Physics · Physics 2019-08-28 Manon Valet , Léa-Laetitia Pontani , Raphaël Voituriez , Elie Wandersman , Alexis M. Prevost

Diffusion of a tagged particle near a constraining biological surface is examined numerically by modeling the surface-water interaction by an effective potential. The effective potential is assumed to be given by an asymmetric double well…

Soft Condensed Matter · Physics 2007-05-23 Arnab Mukherjee , Biman Bagchi

Nanoscale topographic features of solid surfaces can induce complex metastable behavior in colloidal and multiphase systems. Recent studies on single microparticle adsorption at liquid interfaces have reported a crossover from fast…

Soft Condensed Matter · Physics 2018-04-27 Bibin M. Jose , Dhiraj Nandyala , Thomas Cubaud , Carlos E. Colosqui

In response to natural or anthropocentric pollutions coupled to global climate changes, microorganisms from aquatic environments can suddenly accumulate on water surface. These dense suspensions, known as blooms, are harmful to ecosystems…

Biological Physics · Physics 2015-11-16 Julien Dervaux , Annick Méjean , Philippe Brunet

We study the dynamics of a tracer particle (TP) on a comb lattice populated by randomly moving hard-core particles in the dense limit. We first consider the case where the TP is constrained to move on the backbone of the comb only, and, in…

Statistical Mechanics · Physics 2015-12-02 O. Bénichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez

Controlling and suppressing bacterial accumulation at solid surfaces is essential for preventing biofilm formation and biofouling. Whereas various chemical surface treatments are known to reduce cell accumulation and attachment, the role of…

Biological Physics · Physics 2019-05-29 Rachel Mok , Jörn Dunkel , Vasily Kantsler

Toxic cyanobacterial blooms are a growing environmental concern that affects freshwater ecosystems, drinking water supplies, and public health. The cyanobacterium Microcystis is among the most important bloom forming species. It often grows…

Crowded environments modify the diffusion of macromolecules, generally slowing their movement and inducing transient anomalous subdiffusion. The presence of obstacles also modifies the kinetics and equilibrium behavior of tracers. While…