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Photoacoustic microscopy (PAM) is an emerging imaging method combining light and sound. However, limited by the laser's repetition rate, state-of-the-art high-speed PAM technology often sacrifices spatial sampling density (i.e.,…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Tri Vu , Anthony DiSpirito , Daiwei Li , Zixuan Zhang , Xiaoyi Zhu , Maomao Chen , Laiming Jiang , Dong Zhang , Jianwen Luo , Yu Shrike Zhang , Qifa Zhou , Roarke Horstmeyer , Junjie Yao

Delay-and-sum (DAS) is the most widespread digital beamformer in high-frame-rate ultrasound imaging. Its implementation is simple and compatible with real-time applications. In this viewpoint article, we describe the fundamentals of DAS…

Signal Processing · Electrical Eng. & Systems 2021-12-17 Vincent Perrot , Maxime Polichetti , François Varray , Damien Garcia

Iterative image reconstruction algorithms for optoacoustic tomography (OAT), also known as photoacoustic tomography, have the ability to improve image quality over analytic algorithms due to their ability to incorporate accurate models of…

Analysis of PDEs · Mathematics 2015-06-05 Kun wang , Richard Su , Alexander A. Oraevsky , Mark A. Anastasio

Photoacoustic imaging (PAI) is a powerful imaging modality that relies on the PA effect. PAI works on the principle of electromagnetic energy absorption by the exogenous contrast agents and/or endogenous molecules present in the biological…

Optics · Physics 2020-12-16 Mohsin Zafar , Qiuyun Xu , Rayyan Manwar

Photoacoustic imaging (PAI) is a novel medical imaging modality that uses the advantages of the spatial resolution of ultrasound imaging and the high contrast of pure optical imaging. Analytical algorithms are usually employed to…

Signal Processing · Electrical Eng. & Systems 2018-02-27 Moein Mozaffarzadeh , Ali Mahloojifar , Mohammadreza Nasiriavanaki , Mahdi Orooji

Background: Photoacoustic Microscopy (PAM) integrates optical and acoustic imaging, offering enhanced penetration depth for detecting optical-absorbing components in tissues. Nonetheless, challenges arise in scanning large areas with high…

Medical Physics · Physics 2023-12-15 Irem Loc , Mehmet Burcin Unlu

In most photoacoustic (PA) measurements, variations in speed-of-sound (SOS) of the subject are neglected under the assumption of acoustic homogeneity. Biological tissue with spatially heterogeneous SOS cannot be accurately reconstructed…

Photoacoustic tomography is a contrast agent-free imaging technique capable of visualizing blood vessels and tumor-associated vascularization in breast tissue. While sophisticated breast imaging systems have been recently developed, there…

Delay-and-Sum (DAS) is the most common algorithm used in photoacoustic (PA) image formation. However, this algorithm results in a reconstructed image with a wide mainlobe and high level of sidelobes. Minimum variance (MV), as an adaptive…

Signal Processing · Electrical Eng. & Systems 2018-05-11 Roya Paridar , Moein Mozaffarzadeh , Mohammad Mehrmohammadi , Mahdi Orooji

Photoacoustic (PA) imaging technology combines the advantages of optical imaging and ultrasound imaging, showing great potential in biomedical applications. Many preclinical studies and clinical applications urgently require fast,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-13 Yuwei Zheng , Zijian Gao , Yuting Shen , Jiadong Zhang , Daohuai Jiang , Fengyu Liu , Feng Gao , Fei Gao

Based on photoacoustic effect, photoacoustic tomography is developing very fast in recent years, and becoming an important imaging tool for both preclinical and clinical studies. With enough ultrasound transducers placed around the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-13 Jiadong Zhang , Hengrong Lan , Changchun Yang , Shanshan Guo , Feng Gao , Fei Gao

Photoacoustic imaging (PAI) is a novel hybrid imaging technique that combines the benefits of both optical and acoustic imaging modalities, which provides functional and molecular optical contrasts of deep tissue. Commonly used ultrasound…

Medical Physics · Physics 2025-09-24 Xiyu Chen , Junxiang Cai , Rui Zheng , Tao Wu , Fei Gao

Delay-and-sum (DAS) algorithms are widely used for beamforming in linear array photoacoustic imaging systems and are characterized by fast execution. However, these algorithms suffer from various drawbacks like low resolution, low contrast,…

Medical Physics · Physics 2021-07-29 Souradip Paul , Subhamoy Mandal , Mayanglambam Suheshkumar Singh

The most common technique for generating B-mode ultrasound (US) images is delay and sum (DAS) beamforming, where the signals received at the transducer array are sampled before an appropriate delay is applied. This necessitates sampling…

Signal Processing · Electrical Eng. & Systems 2021-03-03 Alon Mamistvalov , Yonina C. Eldar

Collimated beam ultrasound systems are a novel technology for imaging inside multi-layered structures such as geothermal wells. Such systems include a transmitter and multiple receivers to capture reflected signals. Common algorithms for…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Abdulrahman Alanazi , Singanallur Venkatakrishnan , Hector Santos-Villalobos , Gregery Buzzard , Charles Bouman

High-quality three-dimensional (3D) photoacoustic imaging (PAI) is gaining increasing attention in clinical applications. To address the challenges of limited space and high costs, irregular geometric transducer arrays that conform to…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Shuang Li , Yibing Wang , Jian Gao , Chulhong Kim , Seongwook Choi , Yu Zhang , Qian Chen , Yao Yao , Changhui Li

Photoacoustic imaging (PAI) is a promising emerging imaging modality that enables spatially resolved imaging of optical tissue properties up to several centimeters deep in tissue, creating the potential for numerous exciting clinical…

Medical Physics · Physics 2021-04-15 Janek Gröhl , Melanie Schellenberg , Kris Dreher , Lena Maier-Hein

Ultrafast ultrasound localization microscopy (ULM), which has shown promising results in microvascular imaging, overcomes the typical trade-off between resolution and penetration depth. Combining ultrasound contrast agents and high frame…

Signal Processing · Electrical Eng. & Systems 2024-07-02 A. N. Madhavanunni , Niya Mariam Benoy , Mahesh Raveendranatha Panicker , Himanshu Shekhar

Image reconstruction from radio-frequency data is pivotal in ultrafast plane wave ultrasound imaging. Unlike the conventional delay-and-sum (DAS) technique, which relies on somewhat imprecise assumptions, deep learning-based methods perform…

Computer Vision and Pattern Recognition · Computer Science 2023-12-18 Hengrong Lan , Zhiqiang Li , Qiong He , Jianwen Luo

As a hybrid imaging technology, photoacoustic microscopy (PAM) imaging suffers from noise due to the maximum permissible exposure of laser intensity, attenuation of ultrasound in the tissue, and the inherent noise of the transducer.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Da He , Jiasheng Zhou , Xiaoyu Shang , Jiajia Luo , Sung-Liang Chen