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In this paper, we propose a balancing training method to address problems in imbalanced data learning. To this end, we derive a new loss used in the balancing training phase that alleviates the influence of samples that cause an overfitted…

Computer Vision and Pattern Recognition · Computer Science 2021-10-14 Seulki Park , Jongin Lim , Younghan Jeon , Jin Young Choi

Topological accuracy in medical image segmentation is a highly important property for downstream applications such as network analysis and flow modeling in vessels or cell counting. Recently, significant methodological advancements have…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Alexander H. Berger , Nico Stucki , Laurin Lux , Vincent Buergin , Suprosanna Shit , Anna Banaszak , Daniel Rueckert , Ulrich Bauer , Johannes C. Paetzold

Most existing methods handle cell instance segmentation problems directly without relying on additional detection boxes. These methods generally fails to separate touching cells due to the lack of global understanding of the objects. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Jingru Yi , Pengxiang Wu , Qiaoying Huang , Hui Qu , Bo Liu , Daniel J. Hoeppner , Dimitris N. Metaxas

In this study, a multi-task deep neural network is proposed for skin lesion analysis. The proposed multi-task learning model solves different tasks (e.g., lesion segmentation and two independent binary lesion classifications) at the same…

Computer Vision and Pattern Recognition · Computer Science 2017-03-06 Xulei Yang , Zeng Zeng , Si Yong Yeo , Colin Tan , Hong Liang Tey , Yi Su

Complementary-label learning (CLL) is widely used in weakly supervised classification, but it faces a significant challenge in real-world datasets when confronted with class-imbalanced training samples. In such scenarios, the number of…

Machine Learning · Computer Science 2024-03-21 Meng Wei , Yong Zhou , Zhongnian Li , Xinzheng Xu

The task of medical image segmentation presents unique challenges, necessitating both localized and holistic semantic understanding to accurately delineate areas of interest, such as critical tissues or aberrant features. This complexity is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Pranav Singh , Luoyao Chen , Mei Chen , Jinqian Pan , Raviteja Chukkapalli , Shravan Chaudhari , Jacopo Cirrone

This paper presents a new deep regression model, which we call DeepDistance, for cell detection in images acquired with inverted microscopy. This model considers cell detection as a task of finding most probable locations that suggest cell…

Computer Vision and Pattern Recognition · Computer Science 2019-08-30 Can Fahrettin Koyuncu , Gozde Nur Gunesli , Rengul Cetin-Atalay , Cigdem Gunduz-Demir

Target imbalance affects the performance of recent deep learning methods in many medical image segmentation tasks. It is a twofold problem: class imbalance - positive class (lesion) size compared to negative class (non-lesion) size; lesion…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Boris Shirokikh , Alexey Shevtsov , Anvar Kurmukov , Alexandra Dalechina , Egor Krivov , Valery Kostjuchenko , Andrey Golanov , Mikhail Belyaev

A novel method for tackling the problem of imbalanced data in medical image segmentation is proposed in this work. In balanced cross entropy (CE) loss, which is a type of weighted CE loss, the weight assigned to each class is the in-verse…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Seyed Mohsen Hosseini , Mahdieh Soleymani Baghshah

Edge detection (ED) remains a fundamental task in computer vision, yet its performance is often hindered by the ambiguous nature of non-edge pixels near object boundaries. The widely adopted Weighted Binary Cross-Entropy (WBCE) loss treats…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Hao Shu

Melanoma is a fatal skin cancer that is curable and has dramatically increasing survival rate when diagnosed at early stages. Learning-based methods hold significant promise for the detection of melanoma from dermoscopic images. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Saban Ozturk , Tolga Cukur

Separating overlapped nuclei is a major challenge in histopathology image analysis. Recently published approaches have achieved promising overall performance on nuclei segmentation; however, their performance on separating overlapped nuclei…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Haotian Wang , Aleksandar Vakanski , Changfa Shi , Min Xian

For many biological image segmentation tasks, including topological knowledge, such as the nesting of classes, can greatly improve results. However, most `out-of-the-box' CNN models are still blind to such prior information. In this paper,…

Computer Vision and Pattern Recognition · Computer Science 2018-08-22 Marie Piraud , Anjany Sekuboyina , Bjoern H. Menze

Accurate nuclei segmentation in microscopy whole slide images (WSIs) remains challenging due to variability in staining, imaging conditions, and tissue morphology. We propose CellGenNet, a knowledge distillation framework for robust…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Srijan Ray , Bikesh K. Nirala , Jason T. Yustein , Sundaresh Ram

Simultaneous segmentation of multiple organs from different medical imaging modalities is a crucial task as it can be utilized for computer-aided diagnosis, computer-assisted surgery, and therapy planning. Thanks to the recent advances in…

Computer Vision and Pattern Recognition · Computer Science 2021-09-16 Saeid Asgari Taghanaki , Yefeng Zheng , S. Kevin Zhou , Bogdan Georgescu , Puneet Sharma , Daguang Xu , Dorin Comaniciu , Ghassan Hamarneh

In this paper, we focus on the separability of classes with the cross-entropy loss function for classification problems by theoretically analyzing the intra-class distance and inter-class distance (i.e. the distance between any two points…

Machine Learning · Computer Science 2019-09-17 Rudrajit Das , Subhasis Chaudhuri

Class-imbalance is one of the major challenges in real world datasets, where a few classes (called majority classes) constitute much more data samples than the rest (called minority classes). Learning deep neural networks using such…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Saptarshi Sinha , Hiroki Ohashi , Katsuyuki Nakamura

Automatic skin lesion classification from dermoscopy images is important for the early diagnosis of skin diseases such as melanoma. Class imbalance in skin lesion datasets, notably the defects in the representation of malignant(cancerous)…

Quantitative Methods · Quantitative Biology 2025-12-19 Ariful Islam Khandaker , Abdullah Al Shafi , Mohiuddin Ahmad

Cell instance segmentation is a new and challenging task aiming at joint detection and segmentation of every cell in an image. Recently, many instance segmentation methods have applied in this task. Despite their great success, there still…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Menghao Li , Wenquan Feng , Shuchang Lyu , Lijiang Chen , Qi Zhao

Semantic segmentation is a fundamental computer vision task with a vast number of applications. State of the art methods increasingly rely on deep learning models, known to incorrectly estimate uncertainty and being overconfident in…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Luís Almeida , Inês Dutra , Francesco Renna