Related papers: Theory of Morphogenesis
Morphogenesis is a developmental process in which cells organize into shapes and patterns. Complex, multi-factorial models are commonly used to study morphogenesis. It is difficult to understand the relation between the uncertainty in the…
Although models are built on the basis of some observations of reality, the concepts that derive theoretically from their definitions as well as from their characteristics and properties are not necessarily direct consequences of these…
Mathematical models have recently been used to cast doubt on the biotic origin of stromatolites. Here by contrast we propose a biotic model for stromatolite morphogenesis which considers the relationship between upward growth of a…
In model-driven development, an ordered model transformation is a nested set of transformations between source and target classes, in which each transformation is governed by its own pre and post- conditions, but structurally dependent on…
We examine the dependence of a thermodynamic potential of a fluid on the geometry of its container. If motion invariance, continuity, and additivity of the potential are fulfilled, only four morphometric measures are needed to describe…
A description of physical reality in which wholeness is the foundation is discussed along with the motivation for such an attempt. As a possible mathematical framework within which a physical theory based on wholeness may be expressed,…
Morphogenesis involves complex shape changes of biological tissues. Yet, tissue shape changes depend on tissue rheology, which in turn arises from the interplay of large numbers of cells. Here, we link cell- and tissue-scale mechanics by…
We will study the relationship between two well-known theories, genetic evolution and random matrix theory in the context of many-body systems. It is suggested that genetic evolution can be described by a random matrix theory with…
We attempt to provide a comprehensive model of evolution of science across millennia taking into account the contributions of other intellectual traditions, cultural value system and increasing in sophistication of humans in their study of…
We will review some of the theoretical progresses that have been in the study of complex systems in physics and of their applications to biology.
Organogenesis is a tightly regulated process that has been studied experimentally for decades. We are developing mechanistic models for the morphogenesis of limbs, lungs, and kidneys with a view to integrate available knowledge and to…
We present the first image-based generative model of people in clothing for the full body. We sidestep the commonly used complex graphics rendering pipeline and the need for high-quality 3D scans of dressed people. Instead, we learn…
Grammatical forms are said to evolve via two main mechanisms. These are, respectively, the `descent' mechanism, where current forms can be seen to have descended (albeit with occasional modifications) from their roots in ancient languages,…
Our understanding of past evolutionary change is often based on reconstructions based on incomplete data, raising fundamental questions about the degree to which we can make reliable inferences about past evolutionary processes. This was…
"Epigenetic Tracking" is an evo-devo method to generate arbitrary 2d or 3d shapes; as such, it belongs to the field of "artificial embryology". In silico experiments have proved the effectiveness of the method in devo-evolving shapes of any…
Branching morphogenesis generates epithelial trees which facilitate gas exchange, filtering, as well as secretion processes with their large surface to volume ratio. In this review, we focus on the developmental mechanisms that control the…
Polymers consisting of more than one type of monomer, known as copolymers, are vital to both living and synthetic systems. Copolymerisation has been studied theoretically in a number of contexts, often by considering a Markov process in…
Biology is data-rich, and it is equally rich in concepts and hypotheses. Part of trying to understand biological processes and systems is therefore to confront our ideas and hypotheses with data using statistical methods to determine the…
We introduce the existence of a Genus-Type Theory that generalizes classical genus theory by linking fractional ideals of number fields to structures built from their Galois groups and associated Diophantine equations, as formally stated in…
Bone-mass formation in human is looked at to understand the underlying dynamics with an eye on healing of bone-fracture and non-unions in non-invasive pathways. Three biological cells osteoblasts, osteoclasts and osteocytes are important…