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Early detection of Mild Cognitive Impairment (MCI) leads to early interventions to slow the progression from MCI into dementia. Deep Learning (DL) algorithms could help achieve early non-invasive, low-cost detection of MCI. This paper…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Muath Alsuhaibani , Hiroko H. Dodge , Mohammad H. Mahoor

Dementia is a group of irreversible, chronic, and progressive neurodegenerative disorders resulting in impaired memory, communication, and thought processes. In recent years, clinical research advances in brain aging have focused on the…

Computation and Language · Computer Science 2021-02-25 Swati Padhee , Anurag Illendula , Megan Sadler , Valerie L. Shalin , Tanvi Banerjee , Krishnaprasad Thirunarayan , William L. Romine

Mild Cognitive Impairment (MCI) is an early stage of Alzheimer's disease (AD), a form of neurodegenerative disorder. Early identification of MCI is crucial for delaying its progression through timely interventions. Existing research has…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-18 Kristin Qi , Jiatong Shi , Caroline Summerour , John A. Batsis , Xiaohui Liang

The so-called Mild Cognitive Impairment (MCI) or cognitive loss appears in a previous stage before Alzheimer's Disease (AD), but it does not seem sufficiently severe to interfere in independent abilities of daily life, so it usually does…

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises…

Alzheimer's disease (AD) is the most common age-related dementia. Mild cognitive impairment (MCI) is the early stage of cognitive decline before AD. It is crucial to predict the MCI-to-AD conversion for precise management, which remains…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Yiran Wei , Stephen J. Price , Carola-Bibiane Schönlieb , Chao Li

Alzheimer's disease (AD) progresses through distinct stages, from early mild cognitive impairment (EMCI) to late mild cognitive impairment (LMCI) and eventually to AD. Accurate identification of these stages, especially distinguishing LMCI…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Aswini Kumar Patra , Soraisham Elizabeth Devi , Tejashwini Gajurel

Predicting Mild Cognitive Impairment (MCI) is currently a challenge as existing diagnostic criteria rely on neuropsychological examinations. Automated Machine Learning (ML) models that are trained on verbal utterances of MCI patients can…

Computation and Language · Computer Science 2015-12-11 Sylvester Olubolu Orimaye , Kah Yee Tai , Jojo Sze-Meng Wong , Chee Piau Wong

Mild cognitive impairment (MCI) is a high-risk dementia condition which progresses to probable Alzheimer's disease (AD) at approximately 10% to 15% per year. Characterization of group-level differences between two subtypes of MCI - stable…

Neurons and Cognition · Quantitative Biology 2021-06-15 Lu Zhang , Xiaowei Yu , Yanjun Lyu , Li Wang , Dajiang Zhu

Recent progress has been made in detecting early stage dementia entirely through recordings of patient speech. Multimodal speech analysis methods were applied to the PROCESS challenge, which requires participants to use audio recordings of…

Audio and Speech Processing · Electrical Eng. & Systems 2025-02-14 Lei Chi , Arav Sharma , Ari Gebhardt , Joseph T. Colonel

Alzheimer's disease is the most common cause of dementia that affects millions of lives worldwide. Investigating the underlying causes and risk factors of Alzheimer's disease is essential to prevent its progression. Mild Cognitive…

Machine Learning · Computer Science 2023-08-22 Deniz Sezin Ayvaz , Inci M. Baytas

This paper presents a deep learning method using Natural Language Processing (NLP) techniques, to distinguish between Mild Cognitive Impairment (MCI) and Normal Cognitive (NC) conditions in older adults. We propose a framework that analyzes…

Computation and Language · Computer Science 2024-02-06 Ali Pourramezan Fard , Mohammad H. Mahoor , Muath Alsuhaibani , Hiroko H. Dodgec

Early prediction of Mild Cognitive Impairment (MCI) conversion is hampered by a trade-off between immediacy--making fast predictions from a single baseline sMRI--and accuracy--leveraging longitudinal scans to capture disease progression. We…

Machine Learning · Computer Science 2025-06-09 Zhihao Tang , Chaozhuo Li , Litian Zhang , Xi Zhang

Large language models (LLMs) struggle in real-world clinical consultations. Single-turn consultation systems require patients to describe all symptoms at once, which often leads to unclear complaints and vague diagnoses. Traditional…

Computation and Language · Computer Science 2026-05-01 Yichun Feng , Jiawei Wang , Lu Zhou , Yikai Zheng , Zhen Lei , Yixue Li

Early detection of Alzheimer's Dementia (AD) and Mild Cognitive Impairment (MCI) is critical for timely intervention, yet current diagnostic approaches remain resource-intensive and invasive. Speech, encompassing both acoustic and…

This study explores a novel approach to advancing dementia care by integrating socially assistive robotics, reinforcement learning (RL), large language models (LLMs), and clinical domain expertise within a simulated environment. This…

Artificial Intelligence · Computer Science 2025-01-30 Fengpei Yuan , Nehal Hasnaeen , Ran Zhang , Bryce Bible , Joseph Riley Taylor , Hairong Qi , Fenghui Yao , Xiaopeng Zhao

Alzheimer's disease (AD) is one the main causes of dementia in the world and the patients develop severe disability and sometime full dependence. In previous stages Mild Cognitive Impairment (MCI) produces cognitive loss but not severe…

Learning and memory impairments are common characteristics of individuals with mild cognitive impairment (MCI) and mild Alzheimer's disease (miAD). Early diagnosis of MCI is necessary to prevent recurrence of the disease and developing of…

Neurons and Cognition · Quantitative Biology 2021-10-26 Mahmoud Kargar , Alireza Mohammadi

Mild Cognitive Impairment (MCI) is a mental disorder difficult to diagnose. Linguistic features, mainly from parsers, have been used to detect MCI, but this is not suitable for large-scale assessments. MCI disfluencies produce…

Mental health issues, particularly depressive disorders, present significant challenges in contemporary society, necessitating the development of effective automated diagnostic methods. This paper introduces the Agent Mental Clinic (AMC), a…

Computation and Language · Computer Science 2024-10-10 Kunyao Lan , Bingrui Jin , Zichen Zhu , Siyuan Chen , Shu Zhang , Kenny Q. Zhu , Mengyue Wu
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