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In low-resource settings, prevalence mapping relies on empirical prevalence data from a finite, often spatially sparse, set of surveys of communities within the region of interest, possibly supplemented by remotely sensed images that can…

Applications · Statistics 2015-05-27 Peter J. Diggle , Emanuele Giorgi

Multiple diagnostic tests are often used due to limited resources or because they provide complementary information on the epidemiology of a disease under investigation. Existing statistical methods to combine prevalence data from multiple…

Applications · Statistics 2018-08-10 Benjamin Amoah , Emanuele Giorgi , Peter Diggle

Data from multiple prevalence surveys can provide information on common parameters of interest, which can therefore be estimated more precisely in a joint analysis than by separate analyses of the data from each survey. However, fitting a…

Applications · Statistics 2013-12-23 Emanuele Giorgi , Sanie S. S. Sesay , Dianne J. Terlouw , Peter J. Diggle

Maps have long been been used to visualise estimates of spatial variables, in particular disease burden and risk. Predictions made using a geostatistical model have uncertainty that typically varies spatially. However, this uncertainty is…

Applications · Statistics 2020-05-26 Aimee R Taylor , James A Watson , Caroline O Buckee

Infectious diseases remain one of the major causes of human mortality and suffering. Mathematical models have been established as an important tool for capturing the features that drive the spread of the disease, predicting the progression…

Prevalence mapping in low resource settings is an increasingly important endeavor to guide policy making and to spatially and temporally characterize the burden of disease. We will focus our discussion on consideration of the complex design…

Methodology · Statistics 2016-08-15 Jon Wakefield , Daniel Simpson , Jessica Godwin

Malaria transmission in Madagascar is highly heterogeneous, exhibiting spatial, seasonal and long-term trends. Previous efforts to map malaria risk in Madagascar used prevalence data from Malaria Indicator Surveys. These cross-sectional…

Modern disease mapping draws upon a wealth of high resolution spatial data products reflecting environmental and/or socioeconomic factors as covariates, or `features', within a geostatistical framework to improve predictions of disease…

Applications · Statistics 2021-03-16 Rohan Arambepola , Peter Gething , Ewan Cameron

Maps of infectious disease---charting spatial variations in the force of infection, degree of endemicity, and the burden on human health---provide an essential evidence base to support planning towards global health targets. Contemporary…

Applications · Statistics 2017-09-21 Samir Bhatt , Ewan Cameron , Seth R Flaxman , Daniel J Weiss , David L Smith , Peter W Gething

Pooled and individual disease testing are common methods for determining the population prevalences of diseases. Recently, researchers have used Monte Carlo Markov Chain methods to estimate population prevalence from the combined streams of…

Methodology · Statistics 2023-08-23 Matthew Ritch , Charles Copley

Current WHO guidelines set prevalence thresholds below which a Neglected Tropical Disease can be considered to have been eliminated as a public health problem, and specify how surveys to assess whether elimination has been achieved should…

Geostatistical analysis of health data is increasingly used to model spatial variation in malaria prevalence, burden, and other metrics. Traditional inference methods for geostatistical modelling are notoriously computationally intensive,…

Applications · Statistics 2023-05-04 Spencer Wong , Jennifer A. Flegg , Nick Golding , Sevvandi Kandanaarachchi

Understanding the prevalence of key demographic and health indicators in small geographic areas and domains is of global interest, especially in low- and middle-income countries (LMICs), where vital registration data is sparse and household…

Applications · Statistics 2025-04-24 Qianyu Dong , Yunhan Wu , Zehang Richard Li , Jon Wakefield

In almost any geostatistical analysis, one of the underlying, often implicit, modelling assump- tions is that the spatial locations, where measurements are taken, are recorded without error. In this study we develop geostatistical inference…

Applications · Statistics 2017-11-02 Claudio Fronterrè , Emanuele Giorgi , Peter J. Diggle

Model-based geostatistics (MBG) is a subfield of spatial statistics focused on predicting spatially continuous phenomena using data collected at discrete locations. Geostatistical models often rely on the assumptions of stationarity and…

Methodology · Statistics 2024-12-13 Olatunji Johnson , Bedilu A Ejigu , Ezra Gayawan

Improvements to Zambia's malaria surveillance system allow better monitoring of incidence and targetting of responses at refined spatial scales. As transmission decreases, understanding heterogeneity in risk at fine spatial scales becomes…

Objectives: Our research adopts computational techniques to analyze disease outbreaks weekly over a large geographic area while maintaining local-level analysis by incorporating relevant high-spatial resolution cultural and environmental…

Machine Learning · Computer Science 2024-11-12 Scott Pezanowski , Etien Luc Koua , Joseph C Okeibunor , Abdou Salam Gueye

Model-based disease mapping remains a fundamental policy-informing tool in the fields of public health and disease surveillance. Hierarchical Bayesian models have emerged as the state-of-the-art approach for disease mapping since they are…

Machine Learning · Computer Science 2023-07-18 Elizaveta Semenova , Swapnil Mishra , Samir Bhatt , Seth Flaxman , H Juliette T Unwin

The literature on Gaussian graphical models (GGMs) contains two equally rich and equally significant domains of research efforts and interests. The first research domain relates to the problem of graph determination. That is, the underlying…

Methodology · Statistics 2014-11-25 Adrian Dobra

In disease mapping, the aim is to estimate the spatial pattern in disease risk over an extended geographical region, so that areas with elevated risks can be identified. A Bayesian hierarchical approach is typically used to produce such…

Other Statistics · Statistics 2011-08-10 Duncan Lee , Richard Mitchell
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