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A great variety of biologically relevant monolayers present phase coexistence characterized by domains formed by lipids in an ordered phase state dispersed in a continuous, disordered phase. The difference in surface densities between these…

Biological Physics · Physics 2018-02-19 Elena Rufeil Fiori , Natalia Wilke , Adolfo J. Banchio

Lipid domains are found in systems such as multi-component bilayer membranes and single component monolayers at the air-water interface. It was shown by Andelman et al. (Comptes Rendus 301, 675 (1985)) and McConnell et al. (Phys. Chem. {\bf…

Soft Condensed Matter · Physics 2007-05-23 Alex Travesset

We numerically study the dynamics and the phases of self-propelled disk-shaped particles of different sizes with soft repulsive potential in two dimensions. Size diversity is introduced by the polydispersity index (PDI) $\epsilon$, which is…

Soft Condensed Matter · Physics 2022-09-28 Sameer Kumar , Jay Prakash Singh , Debaprasad Giri , Shradha Mishra

We report diffusion coeffcients of micron-scale liquid domains in giant unilamellar vesicles of phospholipids and cholesterol. The trajectory of each domain is tracked, and the mean square displacement grows linearly in time as expected for…

Soft Condensed Matter · Physics 2007-05-23 Pietro Cicuta , Sarah L. Keller , Sarah L. Veatch

We investigate theoretically the behavior of proteins as well as other large macromolecules which are incorporated into amphiphilic monolayers at the air-water interface. We assume the monolayer to be in the coexistence region of the…

Soft Condensed Matter · Physics 2007-05-23 R. R. Netz , D. Andelman , H. Orland

Microphase separation in random multiblock copolymers is studied with mean-field theory assuming that long blocks of a copolymer are strongly segregated, whereas short blocks are able to penetrate into "alien" domains and exchange between…

Soft Condensed Matter · Physics 2021-01-12 E. N. Govorun , A. V. Chertovich

The effect of the adsorption of a polypeptide on the lateral interaction of dimyristoylphosphatidylserine molecules in different phase states on the surface of a 10\,mM KCl aqueous solution has been studied. Changes in the surface pressure…

Molecules at the air-water interface often form inhomogeneous layers in which domains of different densities are separated by sharp interfaces. Complex interfacial pattern formation may occur through the competition of short- and long-range…

patt-sol · Physics 2009-10-30 David K. Lubensky , Raymond E. Goldstein

We report a joint simulation and theoretical study of the liquid-vapor phase behaviour of a fluid in which polydispersity in the particle size couples to the strength of the interparticle interactions. Attention is focussed on the case in…

Statistical Mechanics · Physics 2009-11-11 Nigel B. Wilding , Peter Sollich , Moreno Fasolo , Matteo Buzzacchi

We study the theoretical phase behavior of an asymmetric binary mixture of hard spheres, of which the smaller component is monodisperse and the larger component is polydisperse. The interactions are modelled in terms of the second virial…

Statistical Mechanics · Physics 2019-12-09 Luka Sturtewagen , Erik van der Linden

An investigation of the effect of surface diffusion in random deposition model is made by analytical methods and reasoning. For any given site, the extent to which a particle can diffuse is decided by the morphology in the immediate…

Soft Condensed Matter · Physics 2011-12-14 Baisakhi Mal , Subhankar Ray , J. Shamanna

We formulate a simple effective model to describe molecular interactions in a lipid monolayer. The model represents lipid molecules in terms of two-dimensional anisotropic particles on the plane of the monolayer. These particles interact…

Soft Condensed Matter · Physics 2019-10-02 E. Velasco , L. Mederos

The study of interactions between biomimetic membranes and micron-sized particles is crucial for understanding various biological processes. Here, we control microparticle spontaneous engulfment by giant lipid vesicles by tuning particle…

Soft Condensed Matter · Physics 2025-01-22 Clément Marque , Gaetano D'Avino , Domenico Larobina , Aude Michel , Ali Abou-Hassan , Antonio Stocco

We study the theoretical phase behavior of an asymmetric binary mixture of hard spheres, of which the smaller component is monodisperse and the larger component is polydisperse. The interactions are modeled in terms of the second virial…

Statistical Mechanics · Physics 2019-12-09 Luka Sturtewagen , Erik van der Linden

We report on atomistic simulations of DPPC lipid monolayers using the CHARMM36 lipid force field and four-point OPC water model. The entire two-phase region where domains of the `liquid-condensed' (LC) phase coexist with domains of the…

Soft Condensed Matter · Physics 2019-03-18 S. Panzuela , D. P. Tieleman , L. Mederos , E. Velasco

According to the lipid raft hypothesis, biological lipid membranes are laterally heterogeneous and filled with nanoscale ordered "raft" domains, which are believed to play an important role for the organization of proteins in membranes.…

Biological Physics · Physics 2013-03-22 Sebastian Meinhardt , Richard L. C. Vink , Friederike Schmid

We conduct molecular dynamics computer simulations of a system of Lennard-Jones particles, polydisperse in both size and mass, at a fixed density and temperature. We test for and quantify systematic changes in dynamical properties that…

Statistical Mechanics · Physics 2009-11-07 N. Kiriushcheva , Peter H. Poole

We analyze the effect of polydispersity in the arm number on the effective interactions, structural correlations and the phase behavior of star polymers in a good solvent. The effective interaction potential between two star polymers with…

Soft Condensed Matter · Physics 2009-10-31 Christian von Ferber , Arben Jusufi , Martin Watzlawek , Christos N. Likos , Hartmut Lowen

We discuss different mechanisms for curvature-induced domain formation in multicomponent lipid membranes and present a theoretical model that allows us to study the interplay between the domains. The model represents the membrane by two…

Biological Physics · Physics 2015-11-12 Leonie Brodbek , Friederike Schmid

Liposomes that achieve a heterogeneous and spatially organized surface through phase separation have been recognized to be a promising platform for delivery purposes. However, their design and optimization through experimentation can be…

Soft Condensed Matter · Physics 2021-11-05 Y. Wang , Y. Palzhanov , A. Quaini , M. Olshanskii , S. Majd
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