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We use a stochastic metapopulation model to study the combined effects of seasonality and spatial heterogeneity on disease persistence. We find a pronounced effect of enhanced persistence associated with strong heterogeneity, intermediate…

Populations and Evolution · Quantitative Biology 2015-02-23 Ganna Rozhnova , Ana Nunes , Alan J. McKane

Infectious disease superspreading caused by heterogeneity in contact behavior has been observed to be an important determinant of epidemic dynamics and size in both empirical and theoretical settings. However, it has also been observed that…

Populations and Evolution · Quantitative Biology 2026-01-27 Ari S. Freedman , Bjarke F. Nielsen , Maximillian M. Nguyen , Laurent Hébert-Dufresne , Simon A. Levin

A looming challenge for agriculture is sustainable intensification of food production to feed the growing human population. Current chemical and genetic technologies used to manage plant diseases are highly vulnerable to pathogen evolution…

Populations and Evolution · Quantitative Biology 2014-02-13 Alexey Mikaberidze , Bruce McDonald , Sebastian Bonhoeffer

We develop a new structured compartmental model for the coevolutionary dynamics between susceptible and infectious individuals in heterogeneous SI epidemiological systems. In this model, the susceptible compartment is structured by a…

Populations and Evolution · Quantitative Biology 2024-10-10 Tommaso Lorenzi , Elisa Paparelli , Andrea Tosin

If two species exhibit different nonlinear responses to a single shared resource, and if each species modifies the resource dynamics such that this favors its competitor, they may stably coexist. This coexistence mechanism, known as…

Populations and Evolution · Quantitative Biology 2015-06-16 Florian Hartig , Tamara Münkemüller , Karin Johst , Ulf Dieckmann

Epidemic disease spreading is conventionally often modelled and analyzed by means of rate and diffusion equations, following the paradigms of well-controlled chemical reactions and diffusive dynamics in a test tube. Yet, serious worries…

Physics and Society · Physics 2023-01-03 Klaus Kroy

The relationship between the dynamics of a community and its constituent pairwise interactions is a fundamental problem in ecology. Higher-order ecological effects beyond pairwise interactions may be key to complex ecosystems, but…

Populations and Evolution · Quantitative Biology 2018-09-05 Michael Manhart , Eugene I. Shakhnovich

Many biological populations exhibit diversity in their strategy for survival and reproduction in a given environment, and microbes are an example. We explore the fate of different strategies under sustained environmental change by…

Populations and Evolution · Quantitative Biology 2025-09-24 Ruixi Huang , David Waxman

Built environment supports all the daily activities and shapes our health. Leveraging informative street view imagery, previous research has established the profound correlation between the built environment and chronic, non-communicable…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Zhenyu Han , Yanxin Xi , Tong Xia , Yu Liu , Yong Li

During the recent pandemic, a rise in COVID-19 cases was followed by a decline in influenza. In the absence of cross-immunity, a potential explanation for the observed pattern is behavioral: non-pharmaceutical interventions (NPIs) designed…

Dynamical Systems · Mathematics 2026-04-20 Leah LeJeune , Omar Saucedo , Lauren M. Childs , Navid Ghaffarzadegan

This paper investigates the effects of vaccination on the dynamics of infectious disease, which is spreading in a population concurrently with awareness. The model considers contributions to the overall awareness from a global information…

Quantitative Methods · Quantitative Biology 2018-05-14 G. O. Agaba , Y. N. Kyrychko , K. B. Blyuss

The sustainable use of multicomponent treatments such as combination therapies, combination vaccines/chemicals, and plants carrying multigenic resistance requires an understanding of how their population-wide deployment affects the speed of…

Populations and Evolution · Quantitative Biology 2015-06-16 Romain Bourget , Loïc Chaumont , Natalia Sapoukhina

We study the dynamics of secondary infections on networks, in which only the individuals currently carrying a certain primary infection are susceptible to the secondary infection. In the limit of large sparse networks, the model is mapped…

Probability · Mathematics 2018-05-23 Sam Moore , Peter Mörters , Tim Rogers

Due to the conventional distinction between ecological (rapid) and evolutionary (slow)timescales, ecological and population models to date have typically ignored the effects of evolution. Yet the potential for rapid evolutionary change has…

Populations and Evolution · Quantitative Biology 2012-11-20 Laura E. Jones , Stephen P. Ellner

A common theme among the proposed models for network epidemics is the assumption that the propagating object, i.e., a virus or a piece of information, is transferred across the nodes without going through any modification or evolution.…

Physics and Society · Physics 2019-11-05 Rashad Eletreby , Yong Zhuang , Kathleen M. Carley , Osman Yağan , H. Vincent Poor

The ability to directly record human face-to-face interactions increasingly enables the development of detailed data-driven models for the spread of directly transmitted infectious diseases at the scale of individuals. Complete coverage of…

Networks of person-person contacts form the substrate along which infectious diseases spread. Most network-based studies of the spread focus on the impact of variations in degree (the number of contacts an individual has). However, other…

Quantitative Methods · Quantitative Biology 2008-12-15 Joel C. Miller

The observation that phenotypic variability is ubiquitous in isogenic populations has led to a multitude of experimental and theoretical studies seeking to probe the causes and consequences of this variability. Whether it be in the context…

Populations and Evolution · Quantitative Biology 2022-02-18 Ethan Levien , Jiseon Min , Jane Kondev , Ariel Amir

Population dynamics and evolutionary genetics underly the structure of ecosystems, changing on the same timescale for interacting species with rapid turnover, such as virus (e.g. HIV) and immune response. Thus, an important problem in…

Populations and Evolution · Quantitative Biology 2021-06-17 Cameron J. Browne , Fadoua Yahia

We developed a mathematical model to investigate the role of indirect transmission in the spread of infectious diseases, using the illustrative example of sarcoptic mange as a case study. This disease can be transmitted through direct…

Populations and Evolution · Quantitative Biology 2024-07-19 Tomás Ignacio González , María Fabiana Laguna , Guillermo Abramson