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The role of brain hemodynamics in neurodegenerative diseases cannot be fully assessed using existing imaging technologies. Recently, 2D Dynamic Ultrasound Localization Microscopy (DULM) has allowed for the quantitative mapping of the…

Measurement of the velocity field in thermal-hydraulic experiments is of great importance for phenomena interpretation and code validation. Direct measurement employing Particle Image Velocimetry (PIV) is challenging in some multiphase…

Fluid Dynamics · Physics 2025-09-03 Xicheng Wang , YiMeng Chan , KinWing Wong , Dmitry Grishchenko , Pavel Kudinov

In this paper, we presented the design and development of a new integrated device for measuring heart rate using fingertip to improve estimating the heart rate. As heart related diseases are increasing day by day, the need for an accurate…

Other Computer Science · Computer Science 2016-11-17 M. M. A. Hashem , Rushdi Shams , Md. Abdul Kader , Md. Abu Sayed

Accurate 3D models of the human heart require not only correct outer surfaces but also realistic inner structures, such as the ventricles, atria, and myocardial layers. Approaches relying on implicit surfaces, such as signed distance…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Hieu Le , Jingyi Xu , Nicolas Talabot , Jiancheng Yang , Pascal Fua

Fluid-Structure Interaction (FSI) can be investigated by means of non-linear Finite Element Models (FEM), suitable to capture large deflections of structural parts interacting with fluids, and Computational Fluid Dynamics (CFD). High…

Near-wall blood flow and wall shear stress (WSS) regulate major forms of cardiovascular disease, yet they are challenging to quantify with high fidelity. Patient-specific computational and experimental measurement of WSS suffers from…

Fluid Dynamics · Physics 2021-07-28 Amirhossein Arzani , Jian-Xun Wang , Roshan M. D'Souza

4D Flow Magnetic Resonance Imaging (4D Flow MRI) is a non-invasive measurement technique capable of quantifying blood flow across the cardiovascular system. While practical use is limited by spatial resolution and image noise, incorporation…

Cardiovascular disease affects millions of people worldwide and its social and economic cost clearly motivates scientific research. Computer simulation can lead to a better understanding of cardiac physiology, and for pathology presents…

Biological Physics · Physics 2023-02-27 Toby Simpson

Particle Image Velocimetry (PIV) is fundamental to fluid dynamics, yet deep learning applications face significant hurdles. A critical gap exists: the lack of comprehensive evaluation of how diverse optical flow models perform specifically…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Zicheng Lin , Xiaoqiang Li , Yichao Wang , Chuang Zhu

Recovering the 3D motion of the heart from cine cardiac magnetic resonance (CMR) imaging enables the assessment of regional myocardial function and is important for understanding and analyzing cardiovascular disease. However, 3D cardiac…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Qingjie Meng , Chen Qin , Wenjia Bai , Tianrui Liu , Antonio de Marvao , Declan P O'Regan , Daniel Rueckert

Structured illumination microscopy (SIM) reconstructs a super-resolved image from multiple raw images captured with different illumination patterns; hence, acquisition speed is limited, making it unsuitable for dynamic scenes. We propose a…

Optics · Physics 2025-06-17 Ruiming Cao , Fanglin Linda Liu , Li-Hao Yeh , Laura Waller

Fluorescence microscopy is widely employed for the analysis of living biological samples; however, the utility of the resulting recordings is frequently constrained by noise, temporal variability, and inconsistent visualisation of signals…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Hassan Eshkiki , Sarah Costa , Mostafa Mohammadpour , Farinaz Tanhaei , Christopher H. George , Fabio Caraffini

Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no…

Computational Engineering, Finance, and Science · Computer Science 2021-06-28 Martin R. Pfaller , Jonathan Pham , Nathan M. Wilson , David W. Parker , Alison L. Marsden

Hemodynamic quantities are valuable biomedical risk factors for cardiovascular pathology such as atherosclerosis. Non-invasive, in-vivo measurement of these quantities can only be performed using a select number of modalities that are not…

Quantitative Methods · Quantitative Biology 2026-02-23 Julian Suk , Dieuwertje Alblas , Barbara A. Hutten , Albert Wiegman , Christoph Brune , Pim van Ooij , Jelmer M. Wolterink

In this work we present a novel publicly available stereo based 3D RGB dataset for multi-object zebrafish tracking, called 3D-ZeF. Zebrafish is an increasingly popular model organism used for studying neurological disorders, drug addiction,…

Computer Vision and Pattern Recognition · Computer Science 2020-06-16 Malte Pedersen , Joakim Bruslund Haurum , Stefan Hein Bengtson , Thomas B. Moeslund

In this study, we present a comprehensive numerical analysis of blood flow within human left ventricle models, with particular emphasis on optimizing simulation conditions to enhance the realism and computational efficiency of heart flow…

Voltage-sensitive fluorescence imaging is widely used to image action potential waves in the heart. However, while the electrical waves trigger mechanical contraction, imaging needs to be performed with pharmacologically…

Medical Physics · Physics 2026-03-12 Shrey Chowdhary , Jan Lebert , Shai Dickman , Charles Gordon , Jan Christoph

We developed a Bessel light sheet fluorescence microscopy (LSFM) system to enable high-speed, wide-field intra-vital imaging of zebrafish and other thick biological samples. This system uses air objectives for the convenient mounting of…

Optics · Physics 2023-11-07 Chuhui Wang , Jiaju Chen , Cuiyi Peng , Zhenglin Chen , Dongmei Yu , Peiwu Qin

Particle Image Velocimetry (PIV) is an imaging technique in experimental fluid dynamics that quantifies flow fields around bluff bodies by analyzing the displacement of neutrally buoyant tracer particles immersed in the fluid. Traditional…

Fluid Dynamics · Physics 2025-12-15 Alan Bonomi , Francesco Banelli , Antonio Terpin

Computational cardiovascular flow modeling plays a crucial role in understanding blood flow dynamics. While 3D models provide acute details, they are computationally expensive, especially with fluid-structure interaction (FSI) simulations.…

Fluid Dynamics · Physics 2025-01-06 Hunor Csala , Arvind Mohan , Daniel Livescu , Amirhossein Arzani