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Compound droplets can be used in substance encapsulation and material compartmentalization to achieve a precise control over the relevant processes in many applications, such as bioanalysis, pharmaceutical manufacturing, and material…

Fluid Dynamics · Physics 2018-02-22 Zhizhao Che , Yit Fatt Yap , Tianyou Wang

In this article, we have developed a computational model to determine the droplet formation regime and its transition in a square microfluidic flow-focusing device that eventually dictate the droplet shape, size, and its formation…

Fluid Dynamics · Physics 2025-10-28 Somasekhara Goud Sontti , Arnab Atta

Nowadays, droplet microfluidics has become widely utilized for high-throughput assays. Efficient mixing is crucial for initiating biochemical reactions in many applications. Rapid mixing during droplet formation eliminates the need for…

Fluid Dynamics · Physics 2024-03-01 Ali Kheirkhah Barzoki

This chapter presents an overview of microfluidic devices reported in the literature, used to develop methodologies for nucleation of biomolecules, with crystal size control, and for collecting thermodynamic and kinetic data. Part I is…

Soft Condensed Matter · Physics 2025-12-16 Nadine Candoni , Romain Grossier , Stéphane Veesler

During the past five decades since the discovery of microemulsions by Jack H. Shulman, there have been huge progresses made in applying microemulsion systems in a plethora of research and industrial processes. While it is beyond the scope…

Chemical Physics · Physics 2011-08-16 Kai Lun Lee

This paper presents a new multiphase flow code, cast under an open-source GNU license. The main characteristics of the different flow models are given, then the numerical method used is briefly presented: it includes temporal flow solvers,…

Fluid Dynamics · Physics 2018-05-04 Kevin Schmidmayer , Antoine Marty , Fabien Petitpas , Eric Daniel

Droplet-based microfluidics systems have become widely used in recent years thanks to their advantages, varying from the possibility of handling small fluid volumes to directly synthesizing and encapsulating various living forms for…

We demonstrate a hybrid laser microfabrication approach, which combines the technical merits of ultrafast laser-assisted chemical etching and carbon dioxide laser-induced in-situ melting, for centimeter-scale and bonding-free fabrication of…

Applied Physics · Physics 2022-04-19 Aodong Zhang , Jian Xu , Yucen Li , Ming Hu , Zijie Lin , Yunpeng Song , Jia Qi , Wei Chen , Zhaoxiang Liu , Ya Cheng

A simple method was developed to observe the interference patterns of the light reflected by the interfaces of thin liquid films. Employing a fluorescent microscope with epi-illumination, we collected the 2D patterns of interference fringes…

Optics · Physics 2010-06-14 V. Berejnov , D. Li

One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions. Biomimetic synthetic…

Fluid Dynamics · Physics 2018-07-19 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

We propose a framework using normalizing-flow based models, SELF-Referencing Embedded Strings, and multi-objective optimization that efficiently generates small molecules. With an initial training set of only 100 small molecules, FastFlows…

Chemical Physics · Physics 2022-02-01 Nathan C. Frey , Vijay Gadepally , Bharath Ramsundar

Droplet-based microfluidic devices have substantial promise as cost-effective alternatives to current assessment tools in biological research. Moreover, machine learning models that leverage tabular data, including input design parameters…

Artificial Intelligence · Computer Science 2024-11-12 Dinh-Nguyen Nguyen , Raymond Kai-Yu Tong , Ngoc-Duy Dinh

This review focuses on a microparticle-producing technique widely used for its efficacy in controlling physicochemical properties: droplet-based microfluidics. The review describes the various strategies applied under this technique, and…

Materials Science · Physics 2020-09-16 Cheng Zhang , Romain Grossier , Nadine Candoni , Stéphane Veesler

Lab-on-a-chip (LOC) forms the basis of the new-generation portable analytical systems. LOC allows the manipulation of ultralow flows of liquid reagents and multistep reactions on a microfluidic chip, which requires a robust and precise…

Fluid ferroelectrics, a recently discovered class of liquid crystals that exhibit switchable, long-range polar order, offer opportunities in ultrafast electro-optic technologies, responsive soft matter, and next-generation energy materials.…

Since last decade, graphene has materialized itself as one of the phenomenal materials to modern researchers because of its remarkable thermal, optical, electronic, and mechanical properties. Graphene holds enormous potentials for lab on…

Applied Physics · Physics 2019-10-11 Joydip Sengupta , Chaudhery Mustansar Hussain

Droplets are natural candidates for use as microfluidic reactors, if active control of their formation and transport can be achieved. We show here that localized heating from a laser can block the motion of a water-oil interface, acting as…

Fluid Dynamics · Physics 2015-06-26 C. N. Baroud , J. -P. Delville , F. Gallaire , R. Wunenburger

Process optimization in chemical engineering may be hindered by the limited availability of reliable thermodynamic data for fluid mixtures. Remarkable progress is being made in predicting thermodynamic mixture properties by machine learning…

Computational Engineering, Finance, and Science · Computer Science 2025-10-14 Martin Bubel , Tobias Seidel , Michael Bortz

Microfluidic mixing is a fundamental functionality in most lab on a chip (LOC) systems,whereas realization of efficient mixing is challenging in microfluidic channels due to the small Reynolds numbers. Here, we design and fabricate a…

Applied Physics · Physics 2020-01-10 Wenbo Li , Wei Chu , Peng Wang , Jia Qi , Zhe Wang , Jintian Lin , Min Wang , Ya Cheng

Microfluidic devices are gaining attention for their small size and ability to handle tiny fluid volumes. Mixing fluids efficiently at this scale, known as micromixing, is crucial. This article builds upon previous research by introducing a…