Related papers: Microfluidic tools for assaying immune cell functi…
Petra S. Dittrich is associate professor for Bioanalytics at the Department of Biosystems Science and Engineering at ETH Z\"urich. Here she describes the microfluidic devices that her lab develops to facilitate comprehensive studies on…
Paul Blainey is professor of Biological Engineering at MIT. In this contribution he describes three microfluidic technologies that he and his team has developed to extend the capability, accessibility, and applications of microfluidics: (1)…
Andrew J. deMello is professor of Biochemical Engineering in the Department of Chemistry and Applied Biosciences at ETH Z\"urich. In this contribution he describes the efforts that his lab has undertaken in developing novel microfluidic…
Advances in molecular biology are enabling rapid and efficient analyses for effective intervention in domains such as biology research, infectious disease management, food safety, and biodefense. The emergence of microfluidics and…
A new type of microfluidic system for biological cell manipulation, a CMOS/microfluidic hybrid, is demonstrated. The hybrid system starts with a custom-designed CMOS (complementary metal-oxide semiconductor) chip fabricated in a…
Mehmet Toner is the Helen Andrus Benedict Professor of Biomedical Engineering at the Massachusetts General Hospital (MGH), Harvard Medical School, and Harvard - MIT Health Sciences & Technology. Here he describes his labs efforts to advance…
D. Jed Harrison is a full professor at the Department of Chemistry at the University of Alberta. Here he describes the development of microfluidic techniques in his lab from the initial demonstration of an integrated separation system for…
Shoji Takeushi is professor in and the Director of the Center for International Research on Integrative Biomedical Systems (CIBiS), Institute of Industrial Science (IIS) at the University of Tokyo. Here he describes his attempts to use…
George Whitesides is a Woodford L. and Ann A. Flowers Professor at Harvard University. In this contribution he describes the development of microfluidic techniques, from the spark that ignited this branch of academic research and its…
Albert van den Berg is a full professor on Miniaturized Systems for (Bio)Chemical Analysis at at the University of Twente. In this contribution he describes how microfluidic techniques can be used to mimic xenobiotic metabolism in vitro.…
Organ-on-a-chip (OoCs) platforms could revolutionize drug discovery and might ultimately become essential tools for precision therapy. Although many single-organ and interconnected systems have been described, the immune system has been…
The miniaturization and integration of electronic circuitry has not only made the enormous increase in performance of semiconductor devices possible but also spawned a myriad of new products and applications ranging from a cellular phone to…
Microfluidics and lab-on-a-chip technologies have made it possible to manipulate small volume liquids with unprecedented resolution, automation and integration. However, most current microfluidic systems still rely on bulky off-chip…
Polydimethylsiloxane (PDMS) microfluidic devices have become a standard tool for engineering cells and multicellular networks in vitro. However, the reservoirs, or through-holes where cells access the devices, are usually fabricated…
Molecular communication (MC) is a bio-inspired method of transmitting information using biochemical signals, promising for novel medical, agricultural, and environmental applications at the intersection of bio-, nano-, and communication…
Yoon-Kyoung Cho is a full professor in Biomedical Engineering at UNIST. In this contribution she describes a fully integrated and automated lab-on-a-disc using centrifugal microfluidics to provide a "sample-in and answer-out" type of…
Microfluidic devices have been the subject of considerable attention in recent years. The development of novel microfluidic devices, their evaluation, and their validation requires simulations. While common methods based on Computational…
In the field of biomedicine magnetic beads are used for drug delivery and to treat hyperthermia. Here we propose to use self-organized bead structures to isolate circulating tumor cells using lab-on-chip technologies. Typically blood flows…
Klavs F. Jensen is Warren K. Lewis Professor in Chemical Engineering and Materials Science and Engineering at the Massachusetts Institute of Technology. Here he describes the use of microfluidics for chemical synthesis, from the early…
Bacterial biofilms are among the oldest and most prevalent multicellular life forms on Earth and are increasingly relevant in research areas related to industrial fouling, medicine and biotechnology. The main hurdles to obtaining definitive…