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The interaction between nano- or micro-sized particles and cell membranes is of crucial importance in many biological and biomedical applications such as drug and gene delivery to cells and tissues. During their cellular uptake, the…

This study introduces an open-source computational framework for the generation and permeability evaluation of synthetic porous media. The proposed methodology integrates crystallographic and meshing tools to construct controlled…

Tissues and Organs · Quantitative Biology 2025-02-21 Thomas Lavigne , Camilo Andrés Suarez Afanador , Anas Obeidat , Stéphane Urcun

Metamaterials are composed of periodic subwavelength metal/dielectric structures that resonantly couple to the electric and/or magnetic components of the incident electromagnetic fields, exhibiting properties that are not found in nature.…

Optics · Physics 2016-11-29 Hou-Tong Chen , Antoinette J Taylor , Nanfang Yu

Cell shape changes, essential for processes such as motility or division, are controlled by the actomyosin cortex that actively remodels biological membranes. Their mechanisms can be deciphered in___vitro using biomimetic reconstituted…

A major limitation of two-dimensional scanning electron microscopy (SEM) in imaging porous membranes is its inability to resolve three-dimensional pore architecture and interconnectivity, which are critical factors governing membrane…

Metasurfaces are nano-structured devices composed of arrays of subwavelength scatterers (or meta-atoms) that manipulate the wavefront, polarization, or intensity of light. Like other diffractive optical devices, metasurfaces suffer from…

Optics · Physics 2016-07-22 Ehsan Arbabi , Amir Arbabi , Seyedeh Mahsa Kamali , Yu Horie , Andrei Faraon

As motivated by studies of cellular motility driven by spatiotemporal chemotactic gradients in microdevices, we develop a framework for constructing approximate analytical solutions for the location, speed and cellular densities for cell…

Analysis of PDEs · Mathematics 2022-11-09 Jacobo Ayensa-Jiménez , Mohamed H. Doweidar , Manuel Doblaré , Eamonn A. Gaffney

Biological membranes are known to form various structural motifs, from lipid bilayers to tubular filaments and networks facilitating e.g. adhesion and cell-cell communication. To understand the biophysical processes underpinning lipid-lipid…

Soft Condensed Matter · Physics 2025-12-30 David Regan , Paola Borri , Wolfgang Langbein

Microelectromagnet devices, a ring trap and a matrix, were developed for the microscopic control of biological systems. The ring trap is a circular Au wire with an insulator on top. The matrix has two arrays of straight Au wires, one array…

Quantitative Methods · Quantitative Biology 2007-05-23 H. Lee , A. M. Purdon , R. M. Westervelt

Complex fluid-fluid interfaces featuring mesoscale structures with adsorbed particles are key components of newly designed materials which are continuously enriching the field of soft matter. Simulation tools which are able to cope with the…

Soft Condensed Matter · Physics 2014-02-24 Marcello Sega , Mauro Sbragaglia , Sofia Sergeevna Kantorovich , Alexey Olegovich Ivanov

Most of the performances of electrochemical devices are governed by molecular processes taking place at the solution-electrode interfaces and molecular simulation are the main way to study these processes. Aqueous electrochemical systems…

Chemical Physics · Physics 2019-12-12 Guillaume Jeanmairet , Benjamin Rotenberg , Daniel Borgis , Mathieu Salanne

Microfluidics and lab-on-a-chip technologies have made it possible to manipulate small volume liquids with unprecedented resolution, automation and integration. However, most current microfluidic systems still rely on bulky off-chip…

Instrumentation and Detectors · Physics 2014-05-22 Baichen Li , Lin Li , Allan Guan , Quan Dong , Kangcheng Ruan , Ronggui Hu , Zhenyu Li

We review recent advances in the design, synthesis, and modeling of active fluids. Active fluids have been at the center of many technological innovations and theoretical advances over the past two decades. Research on this new class of…

Soft Condensed Matter · Physics 2023-02-02 Ilham Essafri , Bappa Ghosh , Caroline Desgranges , Jerome Delhommelle

Guided by extensive numerical simulations, we propose a microfluidic device that can sort elastic capsules by their deformability. The device consists of a duct embedded with a semi-cylindrical obstacle, and a diffuser which further…

Fluid Dynamics · Physics 2014-09-18 Lailai Zhu , Cecilia Rorai , Dhrubaditya Mitra , Luca Brandt

Recent works demonstrated that fiber arrays may constitue the basis of an open digital microfluidics. Various processes, such as droplet motion, fragmentation, trapping, release, mixing and encapsulation, may be achieved on fiber arrays.…

Fluid Dynamics · Physics 2015-03-13 Floriane Weyer , Marjorie Lismont , Laurent Dreesen , Nicolas Vandewalle

The study of cells' dynamical properties is essential to a better understanding of several physiological processes. These properties are directly associated with cells' mechanical parameters experimentally achieved through physical stress.…

Soft Condensed Matter · Physics 2022-01-26 G. Ourique , E. F. Teixeira , L. G. Brunnet

Hyperpolarized nuclear magnetic resonance and lab-on-a-chip microfluidics are two dynamic, but until recently quite distinct, fields of research. Recent developments in both areas increased their synergistic overlap. By microfluidic…

Chemical Physics · Physics 2021-09-29 James Eills , William Hale , Marcel Utz

Metasurfaces have shown unprecedented possibilities for wavefront manipulation of waves. The research efforts have been focused on the development of metasurfaces that perform a specific functionality for waves of one physical nature, for…

Optics · Physics 2020-07-29 Ana Díaz-Rubio , Sergei Tretyakov

The transport and manipulation of particles and cells in microfluidic devices has become a core methodology in domains ranging from molecular biology to manufacturing and drug design. The rational design and operation of such devices can…

Computational Engineering, Finance, and Science · Computer Science 2020-07-15 Dmitry Alexeev , Lucas Amoudruz , Sergey Litvinov , Petros Koumoutsakos

Conventional 2-D scanning electron microscopy (SEM) is commonly used to rapidly and qualitatively evaluate membrane pore structure. Quantitative 2-D analyses of pore sizes can be extracted from SEM, but without information about 3-D spatial…

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