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Droplet microfluidics offers a versatile platform for analyzing liquid samples. Despite its potential, there is a lack of techniques that allow to reliably probe individual circulating droplets. The prospect of combining droplet…

Quantitative Methods · Quantitative Biology 2024-03-08 Marc Sulliger , Jaime Ortega Arroyo , Romain Quidant

Petra S. Dittrich is associate professor for Bioanalytics at the Department of Biosystems Science and Engineering at ETH Z\"urich. Here she describes the microfluidic devices that her lab develops to facilitate comprehensive studies on…

Fluid Dynamics · Physics 2018-02-16 Petra S. Dittrich

Microfluidic droplet screens serve as an innovative platform for high-throughput biotechnology, enabling significant advancements in discovery, product optimization, and analysis. This review sheds light on the emerging trend of interaction…

Quantitative Methods · Quantitative Biology 2023-09-11 Carolus Vitalis , Tobias Wenzel

D. Jed Harrison is a full professor at the Department of Chemistry at the University of Alberta. Here he describes the development of microfluidic techniques in his lab from the initial demonstration of an integrated separation system for…

Fluid Dynamics · Physics 2018-02-16 D. Jed Harrison

Mehmet Toner is the Helen Andrus Benedict Professor of Biomedical Engineering at the Massachusetts General Hospital (MGH), Harvard Medical School, and Harvard - MIT Health Sciences & Technology. Here he describes his labs efforts to advance…

Fluid Dynamics · Physics 2018-02-16 Mehmet Toner

In microfluidic systems, droplets undergo intricate deformations as they traverse flow-focusing junctions, posing a challenging task for accurate measurement, especially during short transit times. This study investigates the physical…

Klavs F. Jensen is Warren K. Lewis Professor in Chemical Engineering and Materials Science and Engineering at the Massachusetts Institute of Technology. Here he describes the use of microfluidics for chemical synthesis, from the early…

Fluid Dynamics · Physics 2018-02-16 Klavs F. Jensen

An active area of research interest is the inference of ecological models of complex microbial communities. Inferring such ecological models entails understanding the interactions between microbes and how they affect each other's growth.…

Applications · Statistics 2022-10-19 William Krinsman

Paul Blainey is professor of Biological Engineering at MIT. In this contribution he describes three microfluidic technologies that he and his team has developed to extend the capability, accessibility, and applications of microfluidics: (1)…

Fluid Dynamics · Physics 2018-02-16 Paul Blainey

Droplet-based microfluidic systems are a promising platform forlab-on-a-chip (LoC) applications. These systems can also be used toenhance LoC applications with integrated droplet control information or for data transmission scenarios in the…

Emerging Technologies · Computer Science 2021-01-12 Max Bartunik , Marco Fleischer , Werner Haselmayr , Jens Kirchner

George Whitesides is a Woodford L. and Ann A. Flowers Professor at Harvard University. In this contribution he describes the development of microfluidic techniques, from the spark that ignited this branch of academic research and its…

Fluid Dynamics · Physics 2018-02-16 George Whitesides

Albert van den Berg is a full professor on Miniaturized Systems for (Bio)Chemical Analysis at at the University of Twente. In this contribution he describes how microfluidic techniques can be used to mimic xenobiotic metabolism in vitro.…

Fluid Dynamics · Physics 2018-02-16 Albert van den Berg

This work describes a new microfluidic device developed for rapid screening of solubility diagrams. In several parallel channels, hundreds of nanoliter-volume droplets of a given solution are first stored with a gradual variation in the…

Soft Condensed Matter · Physics 2007-05-23 P. Laval , N. Lisai , J. -B. Salmon , M. Joanicot

Joel Voldman is a professor in the Electrical Engineering and Computer Science Department at MIT. Here he describes his labs efforts to develop microfluidic devices for cell manipulation and analysis.

Fluid Dynamics · Physics 2018-02-16 Joel Voldman

Microfluidics, the study of fluids in microscopic channels, has led to important advances in fields as diverse as microelectronics, biotechnology and chemistry. Microfluidic research is primarily based on the use of microfluidic chips,…

Systems and Control · Electrical Eng. & Systems 2024-07-15 Jorge Vicente Martinez , Edgar Ramirez-Laboreo , Pablo Calderon Gil

Ultrasound-vaporizable microdroplets can be exploited for targeted drug delivery. However, it requires customized microfluidic techniques able to produce monodisperse, capillary-sized and biocompatible multiple emulsions. Recent development…

Soft Condensed Matter · Physics 2019-12-17 E. Teston , V. Hingot , V. Faugeras , C. Errico , M. Bezagu , M. Tanter , O. Couture

High-density microfluidics is becoming an important experimental platform for studying complex biological systems such as synthetic gene regulatory networks, molecular biocomputating of engineered cells, distributing rapid point-of-care…

Biological Physics · Physics 2021-07-21 Sankar Raju Narayanasamy , Ramakrishna Vasireddi , Hoi-Ying Holman

A cryogenic apparatus is described that enables a new experiment, nEDM@SNS, with a major improvement in sensitivity compared to the existing limit in the search for a neutron Electric Dipole Moment (EDM). It uses superfluid $^4$He to…

Droplet-based microfluidic devices have substantial promise as cost-effective alternatives to current assessment tools in biological research. Moreover, machine learning models that leverage tabular data, including input design parameters…

Artificial Intelligence · Computer Science 2024-11-12 Dinh-Nguyen Nguyen , Raymond Kai-Yu Tong , Ngoc-Duy Dinh

We report on experiments that consist in deforming a collection of monodisperse droplets produced by a microfluidic chip through a flow-focusing device. We show that a proper numerical modelling of the flow is necessary to access the stress…

Soft Condensed Matter · Physics 2018-05-23 Corentin Trégouët , Thomas Salez , Cécile Monteux , Mathilde Reyssat
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