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Calcium imaging is one of the most important tools in neurophysiology as it enables the observation of neuronal activity for hundreds of cells in parallel and at single-cell resolution. In order to use the data gained with calcium imaging,…

Neurons and Cognition · Quantitative Biology 2020-04-07 Elke Kirschbaum , Alberto Bailoni , Fred A. Hamprecht

In this chapter, we investigate recently proposed nonlinear conjugate gradient (NCG) methods for shape optimization problems. We briefly introduce the methods as well as the corresponding theoretical background and investigate their…

Optimization and Control · Mathematics 2025-10-14 Sebastian Blauth

We present an unsupervised data-driven approach for non-rigid shape matching. Shape matching identifies correspondences between two shapes and is a fundamental step in many computer vision and graphics applications. Our approach is designed…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Aymen Merrouche , Joao Regateiro , Stefanie Wuhrer , Edmond Boyer

Automated medical image segmentation is an essential task to aid/speed up diagnosis and treatment procedures in clinical practices. Deep convolutional neural networks have exhibited promising performance in accurate and automatic seminal…

Medical Physics · Physics 2022-03-08 Reza Karimzadeh , Emad Fatemizadeh , Hossein Arabi

The robust estimation of dynamically changing features, such as the position of prey, is one of the hallmarks of perception. On an abstract, algorithmic level, nonlinear Bayesian filtering, i.e. the estimation of temporally changing signals…

Neurons and Cognition · Quantitative Biology 2022-01-05 Anna Kutschireiter , Simone Carlo Surace , Henning Sprekeler , Jean-Pascal Pfister

Volumetric image segmentation with convolutional neural networks (CNNs) encounters several challenges, which are specific to medical images. Among these challenges are large volumes of interest, high class imbalances, and difficulties in…

Computer Vision and Pattern Recognition · Computer Science 2019-11-12 Fabian Balsiger , Yannick Soom , Olivier Scheidegger , Mauricio Reyes

Calcium imaging is an important technique for monitoring the activity of thousands of neurons simultaneously. As calcium imaging datasets grow in size, automated detection of individual neurons is becoming important. Here we apply a…

Neurons and Cognition · Quantitative Biology 2016-12-23 Noah J. Apthorpe , Alexander J. Riordan , Rob E. Aguilar , Jan Homann , Yi Gu , David W. Tank , H. Sebastian Seung

We propose a general framework for differentiating shapes represented in binary images with respect to their parameters. This framework functions as an automatic differentiation tool for shape parameters, generating both binary density maps…

Computational Physics · Physics 2024-12-04 Zhaocheng Liu , Jim Bonar

Despite progress in the rapidly developing field of geometric deep learning, performing statistical analysis on geometric data--where each observation is a shape such as a curve, graph, or surface--remains challenging due to the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Emmanuel Hartman , Nicolas Charon

Recent advancements in medical image segmentation techniques have achieved compelling results. However, most of the widely used approaches do not take into account any prior knowledge about the shape of the biomedical structures being…

Image and Video Processing · Electrical Eng. & Systems 2019-09-18 Zhou He , Siqi Bao , Albert Chung

Convolutional neural networks (CNNs) have shown promising results on several segmentation tasks in magnetic resonance (MR) images. However, the accuracy of CNNs may degrade severely when segmenting images acquired with different scanners…

Machine Learning · Statistics 2018-05-28 Neerav Karani , Krishna Chaitanya , Christian Baumgartner , Ender Konukoglu

We present a novel and effective binary representation for convex shapes. We show the equivalence between the shape convexity and some properties of the associated indicator function. The proposed method has two advantages. Firstly, the…

Numerical Analysis · Mathematics 2020-02-25 Shousheng Luo , Xue-Cheng Tai , Yang Wang

In this paper, we propose a novel learning-based framework for 3D shape registration, which overcomes the challenges of significant non-rigid deformation and partiality undergoing among input shapes, and, remarkably, requires no…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Zhangquan Chen , Puhua Jiang , Mingze Sun , Ruqi Huang

Analyzing knee cartilage thickness and strain under load can help to further the understanding of the effects of diseases like Osteoarthritis. A precise segmentation of the cartilage is a necessary prerequisite for this analysis. This…

Dilated Convolutions have been shown to be highly useful for the task of image segmentation. By introducing gaps into convolutional filters, they enable the use of larger receptive fields without increasing the original kernel size. Even…

Computer Vision and Pattern Recognition · Computer Science 2019-03-20 Thomas Ziegler , Manuel Fritsche , Lorenz Kuhn , Konstantin Donhauser

Detection of cell nuclei in microscopic images is a challenging research topic, because of limitations in cellular image quality and diversity of nuclear morphology, i.e. varying nuclei shapes, sizes, and overlaps between multiple cell…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Mohammad Tofighi , Tiantong Guo , Jairam K. P. Vanamala , Vishal Monga

Cell nuclei segmentation is one of the most important tasks in the analysis of biomedical images. With ever-growing sizes and amounts of three-dimensional images to be processed, there is a need for better and faster segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Julian Arz , Peter Sanders , Johannes Stegmaier , Ralf Mikut

We present a filter based approach for inbetweening. We train a convolutional neural network to generate intermediate frames. This network aim to generate smooth animation of line drawings. Our method can process scanned images directly.…

Computer Vision and Pattern Recognition · Computer Science 2017-06-13 Yuichi Yagi

This work describes a novel methodology for automatic contour extraction from 2D images of 3D neurons (e.g. camera lucida images and other types of 2D microscopy). Most contour-based shape analysis methods can not be used to characterize…

Computer Vision and Pattern Recognition · Computer Science 2008-10-24 J. J. G. Leandro , R. M. Cesar , L. da F. Costa

Vessel segmentation of retinal images is a key diagnostic capability in ophthalmology. This problem faces several challenges including low contrast, variable vessel size and thickness, and presence of interfering pathology such as…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Venkateswararao Cherukuri , Vijay Kumar BG , Raja Bala , Vishal Monga