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Inferring parameters of models of biochemical kinetics from single-cell data remains challenging because of the uncertainty arising from the intractability of the likelihood function of stochastic reaction networks. Such uncertainty falls…

Quantitative Methods · Quantitative Biology 2025-01-14 Zekai Li , Mauricio Barahona , Philipp Thomas

While Deep Neural Networks (DNNs) achieve state-of-the-art accuracy in various applications, they often fall short in accurately estimating their predictive uncertainty and, in turn, fail to recognize when these predictions may be wrong.…

Machine Learning · Computer Science 2020-07-22 Ankur Mallick , Chaitanya Dwivedi , Bhavya Kailkhura , Gauri Joshi , T. Yong-Jin Han

Bayesian Neural Networks (BayNNs) naturally provide uncertainty in their predictions, making them a suitable choice in safety-critical applications. Additionally, their realization using memristor-based in-memory computing (IMC)…

Machine Learning · Computer Science 2024-01-24 Soyed Tuhin Ahmed , Kamal Danouchi , Guillaume Prenat , Lorena Anghel , Mehdi B. Tahoori

Increasing effort is put into the development of methods for learning mechanistic models from data. This task entails not only the accurate estimation of parameters but also a suitable model structure. Recent work on the discovery of…

Machine Learning · Computer Science 2024-07-01 Justin N. Kreikemeyer , Philipp Andelfinger , Adelinde M. Uhrmacher

This study introduces a new normalization layer termed Batch Layer Normalization (BLN) to reduce the problem of internal covariate shift in deep neural network layers. As a combined version of batch and layer normalization, BLN adaptively…

Machine Learning · Computer Science 2023-01-16 Amir Ziaee , Erion Çano

Uncertainty estimation is important for ensuring safety and robustness of AI systems. While most research in the area has focused on un-structured prediction tasks, limited work has investigated general uncertainty estimation approaches for…

Machine Learning · Statistics 2021-02-12 Andrey Malinin , Mark Gales

We study statistical inference and distributionally robust solution methods for stochastic optimization problems, focusing on confidence intervals for optimal values and solutions that achieve exact coverage asymptotically. We develop a…

Machine Learning · Statistics 2018-07-03 John Duchi , Peter Glynn , Hongseok Namkoong

Despite the recent success of stochastic gradient descent in deep learning, it is often difficult to train a deep neural network with an inappropriate choice of its initial parameters. Even if training is successful, it has been known that…

Machine Learning · Computer Science 2023-02-10 Cheolhyoung Lee , Kyunghyun Cho

Decomposing prediction uncertainty into aleatoric (irreducible) and epistemic (reducible) components is critical for the reliable deployment of machine learning systems. While the mutual information between the response variable and model…

Machine Learning · Statistics 2026-02-10 Anchit Jain , Stephen Bates

Stochastic simulation has been widely used to analyze the performance of complex stochastic systems and facilitate decision making in those systems. Stochastic simulation is driven by the input model, which is a collection of probability…

Risk Management · Quantitative Finance 2020-02-14 Tianyi Liu , Enlu Zhou

It is widely believed that the implicit regularization of SGD is fundamental to the impressive generalization behavior we observe in neural networks. In this work, we demonstrate that non-stochastic full-batch training can achieve…

Machine Learning · Computer Science 2022-04-21 Jonas Geiping , Micah Goldblum , Phillip E. Pope , Michael Moeller , Tom Goldstein

Batch normalization is currently the most widely used variant of internal normalization for deep neural networks. Additional work has shown that the normalization of weights and additional conditioning as well as the normalization of…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Wolfgang Fuhl , Enkelejda Kasneci

It is a long-standing objective to ease the computation burden incurred by the decision making process. Identification of this mechanism's sensitivity to simplification has tremendous ramifications. Yet, algorithms for decision making under…

Artificial Intelligence · Computer Science 2021-05-13 Andrey Zhitnikov , Vadim Indelman

Assessing sampling uncertainty in extremum estimation can be challenging when the asymptotic variance is not analytically tractable. Bootstrap inference offers a feasible solution but can be computationally costly especially when the model…

Econometrics · Economics 2020-09-15 Jean-Jacques Forneron , Serena Ng

Neural networks are powerful function approximators with tremendous potential in learning complex distributions. However, they are prone to overfitting on spurious patterns. Bayesian inference provides a principled way to regularize neural…

Machine Learning · Computer Science 2024-12-02 Yanzhe Bekkemoen , Helge Langseth

Bayesian neural networks (BNNs) have recently regained a significant amount of attention in the deep learning community due to the development of scalable approximate Bayesian inference techniques. There are several advantages of using a…

Machine Learning · Statistics 2023-05-02 Aliaksandr Hubin , Geir Storvik

Though deep neural networks have achieved impressive success on various vision tasks, obvious performance degradation still exists when models are tested in out-of-distribution scenarios. In addressing this limitation, we ponder that the…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Xiaotong Li , Zixuan Hu , Jun Liu , Yixiao Ge , Yongxing Dai , Ling-Yu Duan

Despite the significant success of deep learning in computer vision tasks, cross-domain tasks still present a challenge in which the model's performance will degrade when the training set and the test set follow different distributions.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Lei Qi , Dongjia Zhao , Yinghuan Shi , Xin Geng

Classical statistical learning theory predicts that overparameterized models should exhibit severe overfitting, yet modern deep neural networks with far more parameters than training samples consistently generalize well. This contradiction…

Machine Learning · Computer Science 2026-04-10 Zeran Johannsen

Mini-batch stochastic gradient descent and variants thereof have become standard for large-scale empirical risk minimization like the training of neural networks. These methods are usually used with a constant batch size chosen by simple…

Machine Learning · Computer Science 2017-06-29 Lukas Balles , Javier Romero , Philipp Hennig
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