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Finding an appropriate representation of dynamic activities in the brain is crucial for many downstream applications. Due to its highly dynamic nature, temporally averaged fMRI (functional magnetic resonance imaging) can only provide a…

Machine Learning · Computer Science 2022-08-18 Sikun Lin , Shuyun Tang , Scott Grafton , Ambuj Singh

Diffusional kurtosis imaging (DKI) is a methodology for measuring the extent of non-Gaussian diffusion in biological tissue, which has shown great promise in clinical diagnosis, treatment planning and monitoring of many neurological…

Image and Video Processing · Electrical Eng. & Systems 2024-04-29 Megan E. Farquhar , Qianqian Yang , Viktor Vegh

Tract-specific diffusion measures, as derived from brain diffusion MRI, have been linked to white matter tract structural integrity and neurodegeneration. As a consequence, there is a large interest in the automatic segmentation of white…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Bo Li , Marius de Groot , Meike Vernooij , Arfan Ikram , Wiro Niessen , Esther Bron

Purpose: In diffusion MRI (dMRI), the volumetric and bundle analyses of whole-brain tissue microstructure and connectivity can be severely impeded by an incomplete field-of-view (FOV). This work aims to develop a method for imputing the…

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

Machine Learning · Computer Science 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

We propose a novel integrated framework that jointly models complementary information from resting-state functional MRI (rs-fMRI) connectivity and diffusion tensor imaging (DTI) tractography to extract biomarkers of brain connectivity…

Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

Neurons and Cognition · Quantitative Biology 2025-02-25 Bishal Thapaliya , Robyn Miller , Jiayu Chen , Yu-Ping Wang , Esra Akbas , Ram Sapkota , Bhaskar Ray , Pranav Suresh , Santosh Ghimire , Vince Calhoun , Jingyu Liu

In vivo cardiac diffusion tensor imaging (cDTI) is a promising Magnetic Resonance Imaging (MRI) technique for evaluating the micro-structure of myocardial tissue in the living heart, providing insights into cardiac function and enabling the…

White matter fiber clustering is an important strategy for white matter parcellation, which enables quantitative analysis of brain connections in health and disease. In combination with expert neuroanatomical labeling, data-driven white…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Yuqian Chen , Chaoyi Zhang , Tengfei Xue , Yang Song , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

Segmenting deep brain structures from magnetic resonance images is important for patient diagnosis, surgical planning, and research. Most current state-of-the-art solutions follow a segmentation-by-registration approach, where subject MRIs…

Image and Video Processing · Electrical Eng. & Systems 2022-05-20 Mehri Baniasadi , Mikkel V. Petersen , Jorge Goncalves , Andreas Horn , Vanja Vlasov , Frank Hertel , Andreas Husch

Tractography algorithms are used extensively to delineate white matter structures, by operating on the voxel-wise information generated through the application of diffusion tensor imaging (DTI) or other models to diffusion weighted (DW)…

Quantitative Methods · Quantitative Biology 2024-03-05 Richard G. Carson , Alexander Leemans

Background: Recent studies have indicated that functional connectivity is dynamic even during rest. A common approach to modeling the dynamic functional connectivity in whole-brain resting-state fMRI is to compute the correlation between…

Neurons and Cognition · Quantitative Biology 2019-11-05 Shih-Gu Huang , S. Balqis Samdin , Chee-Ming Ting , Hernando Ombao , Moo K. Chung

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

Neurons and Cognition · Quantitative Biology 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Current theories hold that brain function is highly related to long-range physical connections through axonal bundles, namely extrinsic connectiv-ity. However, obtaining a groupwise cortical parcellation based on extrinsic connectivity…

Applications · Statistics 2017-01-06 Guillermo Gallardo , William Wells , Rachid Deriche , Demian Wassermann

Data-driven brain parcellations aim to provide a more accurate representation of an individual's functional connectivity, since they are able to capture individual variability that arises due to development or disease. This renders…

Neurons and Cognition · Quantitative Biology 2017-03-30 Sofia Ira Ktena , Salim Arslan , Sarah Parisot , Daniel Rueckert

The thalamus consists of several histologically and functionally distinct nuclei increasingly implicated in brain pathology and important for treatment, motivating the need for development of fast and accurate thalamic segmentation. The…

Image and Video Processing · Electrical Eng. & Systems 2019-12-19 Charles Iglehart , Martin Monti , Joshua Cain , Thomas Tourdias , Manojkumar Saranathan

Geostatistical modeling for continuous point-referenced data has been extensively applied to neuroimaging because it produces efficient and valid statistical inference. However, diffusion tensor imaging (DTI), a neuroimaging characterizing…

Purpose: Functional Magnetic Resonance Imaging (fMRI) data acquired through resting-state studies have been used to obtain information about the spontaneous activations inside the brain. One of the approaches for analysis and interpretation…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Harshit Parmar , Brian Nutter , Rodney Long , Sameer Antani , Sunanda Mitra

Motivated by the need to model the dependence between regions of interest in functional neuroconnectivity for efficient inference, we propose a new sampling-based Bayesian clustering approach for covariance structures of high-dimensional…

Methodology · Statistics 2024-01-09 Hyoshin Kim , Sujit K. Ghosh , Adriana Di Martino , Emily C. Hector

Purpose: To develop an algorithm for robust partial Fourier (PF) reconstruction applicable to diffusion-weighted (DW) images with non-smooth phase variations. Methods: Based on an unrolled proximal splitting algorithm, a neural network…

Image and Video Processing · Electrical Eng. & Systems 2022-01-11 Fasil Gadjimuradov , Thomas Benkert , Marcel Dominik Nickel , Andreas Maier
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