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Deep convolutional neural networks (CNNs) are state-of-the-art for semantic image segmentation, but typically require many labeled training samples. Obtaining 3D segmentations of medical images for supervised training is difficult and labor…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Zhenlin Xu , Marc Niethammer

Automated detection and segmentation of surgical devices, such as catheters or wires, in X-ray fluoroscopic images have the potential to enhance image guidance in minimally invasive heart surgeries. In this paper, we present a convolutional…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Lin Xi , Yingliang Ma , Ethan Koland , Sandra Howell , Aldo Rinaldi , Kawal S. Rhode

Cryo-electron microscopy (cryo-EM) has emerged as a powerful technique for determining the three-dimensional structures of biological molecules at near-atomic resolution. However, reconstructing helical assemblies presents unique challenges…

Quantitative Methods · Quantitative Biology 2026-03-16 Guy Shapira , Yoel Shkolnisky

Automatic segmentation of multiple organs and tumors from 3D medical images such as magnetic resonance imaging (MRI) and computed tomography (CT) scans using deep learning methods can aid in diagnosing and treating cancer. However, organs…

Image and Video Processing · Electrical Eng. & Systems 2022-07-25 Hao Li , Yang Nan , Javier Del Ser , Guang Yang

This paper presents a novel unsupervised segmentation method for 3D medical images. Convolutional neural networks (CNNs) have brought significant advances in image segmentation. However, most of the recent methods rely on supervised…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Takayasu Moriya , Holger R. Roth , Shota Nakamura , Hirohisa Oda , Kai Nagara , Masahiro Oda , Kensaku Mori

Image segmentation plays a pivotal role in several medical-imaging applications by assisting the segmentation of the regions of interest. Deep learning-based approaches have been widely adopted for semantic segmentation of medical data. In…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Abhishek Shivdeo , Rohit Lokwani , Viraj Kulkarni , Amit Kharat , Aniruddha Pant

On-line segmentation of the uterus can aid effective image-based guidance for precise delivery of dose to the target tissue (the uterocervix) during cervix cancer radiotherapy. 3D ultrasound (US) can be used to image the uterus, however,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Bahareh Behboodi , Hassan Rivaz , Susan Lalondrelle , Emma Harris

Protein structure prediction models are now capable of generating accurate 3D structural hypotheses from sequence alone. However, they routinely fail to capture the conformational diversity of dynamic biomolecular complexes, often requiring…

Machine Learning · Computer Science 2025-12-02 Rishwanth Raghu , Axel Levy , Gordon Wetzstein , Ellen D. Zhong

Deep learning architecture with convolutional neural network (CNN) achieves outstanding success in the field of computer vision. Where U-Net, an encoder-decoder architecture structured by CNN, makes a great breakthrough in biomedical image…

Image and Video Processing · Electrical Eng. & Systems 2023-02-13 Qing Xu , Zhicheng Ma , Na HE , Wenting Duan

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

Accurate segmentation of 3-D cell nuclei in microscopy images is essential for the study of nuclear organization, gene expression, and cell morphodynamics. Current image segmentation methods are challenged by the complexity and variability…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Sundaresh Ram , Jeffrey J. Rodriguez

Accurate segmentation of critical anatomical structures is at the core of medical image analysis. The main bottleneck lies in gathering the requisite expert-labeled image annotations in a scalable manner. Methods that permit to produce…

Computer Vision and Pattern Recognition · Computer Science 2020-07-09 Yuhang Lu , Weijian Li , Kang Zheng , Yirui Wang , Adam P. Harrison , Chihung Lin , Song Wang , Jing Xiao , Le Lu , Chang-Fu Kuo , Shun Miao

The past decade's "cryoEM revolution" has produced exponential growth in high-resolution structural data through advances in cryogenic electron microscopy (cryoEM) and tomography (cryoET). Deep learning integration into structural…

Quantitative Methods · Quantitative Biology 2025-07-29 Brady K. Zhou , Jason J. Hu , Jane K. J. Lee , Z. Hong Zhou , Demetri Terzopoulos

Segmentation of white matter lesions and deep grey matter structures is an important task in the quantification of magnetic resonance imaging in multiple sclerosis. In this paper we explore segmentation solutions based on convolutional…

We present an efficient deep learning approach for the challenging task of tumor segmentation in multisequence MR images. In recent years, Convolutional Neural Networks (CNN) have achieved state-of-the-art performances in a large variety of…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

Deep learning has demonstrated superb efficacy in processing imaging data, yet its suitability in solving challenging inverse problems in scientific imaging has not been fully explored. Of immense interest is the determination of local…

Materials Science · Physics 2019-02-20 Nouamane Laanait , Qian He , Albina Y. Borisevich

There exist two groups of electron microscopy methods that are capable of providing three-dimensional (3D) structural information of an object, i.e., electron tomography and depth sectioning. Electron tomography is capable of resolving…

Materials Science · Physics 2024-05-28 Liangze Mao , Jizhe Cui , Rong Yu

Autoencoding, which aims to reconstruct the input images through a bottleneck latent representation, is one of the classic feature representation learning strategies. It has been shown effective as an auxiliary task for semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2023-03-20 Yuhao Lin , Haiming Xu , Lingqiao Liu , Jinan Zou , Javen Qinfeng Shi

Live cell microscopy sequences exhibit complex spatial structures and complicated temporal behaviour, making their analysis a challenging task. Considering cell segmentation problem, which plays a significant role in the analysis, the…

Computer Vision and Pattern Recognition · Computer Science 2019-01-08 Assaf Arbelle , Tammy Riklin Raviv

Biological membranes are one of the most basic structures and regions of interest in cell biology. In the study of membranes, segment extraction is a well-known and difficult problem because of impeding noise, directional and thickness…

Computer Vision and Pattern Recognition · Computer Science 2018-10-24 Joris Roels , Jonas De Vylder , Jan Aelterman , Yvan Saeys , Wilfried Philips
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