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Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers…

Instrumentation and Detectors · Physics 2015-06-22 George Korir , Manu Prakash

The paper describes a novel concept for a low cost microfluidic platform utilizing materials and processes used in low cost thermal inkjet printing. The concept re-purposes the jetting elements to create pumps, mixers, and valves all…

Fluid Dynamics · Physics 2016-10-28 Alexander N. Govyadinov , Erik Torniainen , Pavel Kornilovitch , David Markel

Precise manipulation of fluids and objects on the micro scale is seldom a simple task, but nevertheless crucial for many applications in life sciences and chemical engineering. We present a microfluidic chip fabricated in silicon-glass,…

Microfluidic valves play a key role within microfluidic systems by regulating fluid flow through distinct microchannels, enabling many advanced applications in medical diagnostics, lab-on-chips, and laboratory automation. While microfluidic…

Materials Science · Physics 2023-12-19 Tinku Supakar , David Space , Sophy Meija , Rou Yu Tan , Jeffrey R. Alston , Eric A. Josephs

Inertial pumping is a promising new method of moving fluids through microchannels but many of its properties remain unexplored. In this work, inertial flow rates are investigated for different channel lengths, operating temperatures, and…

Fluid Dynamics · Physics 2022-02-03 Pavel E. Kornilovitch , Tyler Cochell , Alexander N. Govyadinov

Large-scale microfluidic microsystems with complex three-dimensional (3D) configurations are highly in demand by both fundamental research and industrial application, holding the potentials for fostering a wide range of innovative…

Applied Physics · Physics 2020-01-13 Zijie Lin , Jian Xu , Yunpeng Song , Xiaolong Li , Peng Wang , Wei Chu , Zhenhua Wang , Ya Cheng

Fluid flow along microchannels can be induced by keeping opposite walls at different temperatures, and placing elongated tilted pillars inside the channel. The driving force for this fluid motion arises from the anisotropic thermophoretic…

Soft Condensed Matter · Physics 2019-05-07 Zihan Tan , Mingcheng Yang , Marisol Ripoll

The fundamental action of the bubble-driven inertial micropump is investigated. The pump has no moving parts and consists of a thermal resistor placed asymmetrically within a straight channel connecting two reservoirs. Using numerical…

We report a novel technique to passively create strong secondary flows at moderate to high flow rates in microchannels, accurately control them and finally, due to their deterministic nature, program them into microfluidic platforms. Based…

Fluid Dynamics · Physics 2011-10-20 Hamed Amini , Mahdokht Masaeli , Dino Di Carlo

Inexpensive, portable lab-on-a-chip devices would revolutionize fields like environmental monitoring and global health, but current microfluidic chips are tethered to extensive off-chip hardware. Insects, however, are self-contained and…

Biomedical and biochemical processes in paper-based microfluidic devices often deal with mixing of two analytes to perform important functions. Uniform mixing of analytes in paper matrix is a challenging proposition, often necessitating…

Flows of particles through bottlenecks are ubiquitous in nature and industry, involving both dry granular materials and suspensions. However, practical limitations of conventional experimental setups hinder the full understanding of these…

Soft Condensed Matter · Physics 2025-07-02 Lars Kool , Jules Tampier , Philippe Bourrianne , Anke Lindner

Microfluidic devices are increasingly used in synchrotron-based experiments to deliver and probe liquid samples, offering advantages such as minimal sample consumption and reduced radiation damage. Despite their growing use, few devices…

Despite several decades of development, microfluidics lacks a sealing material that can be readily fabricated, leak-tight under high liquid water pressure, stable over a long time, and vacuum compatible. In this paper, we report the…

Microfluidics, the study of fluids in microscopic channels, has led to important advances in fields as diverse as microelectronics, biotechnology and chemistry. Microfluidic research is primarily based on the use of microfluidic chips,…

Systems and Control · Electrical Eng. & Systems 2024-07-15 Jorge Vicente Martinez , Edgar Ramirez-Laboreo , Pablo Calderon Gil

Ultrasound-vaporizable microdroplets can be exploited for targeted drug delivery. However, it requires customized microfluidic techniques able to produce monodisperse, capillary-sized and biocompatible multiple emulsions. Recent development…

Soft Condensed Matter · Physics 2019-12-17 E. Teston , V. Hingot , V. Faugeras , C. Errico , M. Bezagu , M. Tanter , O. Couture

Developing an organoid computing platform from neurons in vitro demands stable, precisely controlled microenvironments. To address this requirement, we designed, simulated, and fabricated a microfluidic device featuring hexagonal wells…

Fluid Dynamics · Physics 2025-08-04 Maxx Yung

Microfluidics is an established multidisciplinary research domain with widespread applications in the fields of medicine, biotechnology and engineering. Conventional production methods of microfluidic chips have been limited to planar…

Chemical reactions and biological processes are often governed by the structure and transport dynamics of the interface between two liquid phases. Despite their importance, our microscopic understanding of liquid-liquid interfaces has been…

To facilitate the use and portability of Lab on a chip technology, it is desirable to avoid the use of bulky electronic systems for flow control. Developed self-powered microsystems typically move only small volumes of fluid performing up…

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