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Compact Genetic Algorithms (cGAs) are condensed variants of classical Genetic Algorithms (GAs) that use a probability vector representation of the population instead of the complete population. cGAs have been shown to significantly reduce…

Neural and Evolutionary Computing · Computer Science 2025-04-07 Prasanta Dutta , Anirban Mukhopadhyay

Reducing the number of false discoveries is presently one of the most pressing issues in the life sciences. It is of especially great importance for many applications in neuroimaging and genomics, where datasets are typically…

Methodology · Statistics 2018-06-26 Alexej Gossmann , Pascal Zille , Vince Calhoun , Yu-Ping Wang

Multiview analysis aims at extracting shared latent components from data samples that are acquired in different domains, e.g., image, text, and audio. Classic multiview analysis, e.g., canonical correlation analysis (CCA), tackles this…

Machine Learning · Computer Science 2020-06-24 Qi Lyu , Xiao Fu

Diverse applications - particularly in tumour subtyping - have demonstrated the importance of integrative clustering techniques for combining information from multiple data sources. Cluster-Of-Clusters Analysis (COCA) is one such approach…

Machine Learning · Statistics 2020-08-05 Alessandra Cabassi , Paul D. W. Kirk

Canonical correlation analysis is a classic well-known multivariate statistical method focusing on the relationships between two sets of variables. The visualisation of those relationships can be achieved by means of a biplot of the…

Methodology · Statistics 2026-04-02 Jan Graffelman

Integrative analyses of different high dimensional data types are becoming increasingly popular. Similarly, incorporating prior functional relationships among variables in data analysis has been a topic of increasing interest as it helps…

Methodology · Statistics 2016-06-09 Sandra E. Safo , Shuzhao Li , Qi Long

Drug discovery is the process of identifying compounds which have potentially meaningful biological activity. A major challenge that arises is that the number of compounds to search over can be quite large, sometimes numbering in the…

Applications · Statistics 2012-02-16 Daniel Samarov , J. S. Marron , Yufeng Liu , Christopher Grulke , Alexander Tropsha

Modern vision pipelines increasingly rely on pretrained image encoders whose representations are reused across tasks and models, yet these representations are often overcomplete and model-specific. We propose a simple, training-free method…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Dylan B. Lewis , Jens Gregor , Hector Santos-Villalobos

This paper considers canonical correlation analysis for two longitudinal variables that are possibly sampled at different time resolutions with irregular grids. We modeled trajectories of the multivariate variables using random effects and…

Applications · Statistics 2023-02-03 Seonjoo Lee , Jongwoo Choi , Zhiqian Fang , F. DuBois Bowman

Principal Component Analysis (PCA) and other multi-variate models are often used in the analysis of "omics" data. These models contain much information which is currently neither easily accessible nor interpretable. Here we present an…

Genomics · Quantitative Biology 2021-11-18 Nordine Aouni , Luc Linders , David Robinson , Len Vandelaer , Jessica Wiezorek , Geetesh Gupta , Rachel Cavill

Principal component analysis (PCA) is a well-established tool in machine learning and data processing. The principal axes in PCA were shown to be equivalent to the maximum marginal likelihood estimator of the factor loading matrix in a…

Methodology · Statistics 2019-10-25 Mengyang Gu , Weining Shen

We introduce three novel semi-parametric extensions of probabilistic canonical correlation analysis with identifiability guarantees. We consider moment matching techniques for estimation in these models. For that, by drawing explicit links…

Machine Learning · Statistics 2016-06-06 Anastasia Podosinnikova , Francis Bach , Simon Lacoste-Julien

Independent component analysis (ICA) is a method for recovering statistically independent signals from observations of unknown linear combinations of the sources. Some of the most accurate ICA decomposition methods require searching for the…

Machine Learning · Statistics 2016-09-23 Matan Sela , Ron Kimmel

Many unsupervised kernel methods rely on the estimation of the kernel covariance operator (kernel CO) or kernel cross-covariance operator (kernel CCO). Both kernel CO and kernel CCO are sensitive to contaminated data, even when bounded…

Machine Learning · Statistics 2017-05-12 Md. Ashad Alam , Kenji Fukumizu , Yu-Ping Wang

The matched case-control design, up until recently mostly pertinent to epidemiological studies, is becoming customary in biomedical applications as well. For instance, in omics studies, it is quite common to compare cancer and healthy…

Methodology · Statistics 2024-02-05 Vera Djordjilović , Erica Ponzi , Therese Haugdahl Nøst , Magne Thoresen

Interpreting the internal reasoning of vision-language models is essential for deploying AI in safety-critical domains. Concept-based explainability provides a human-aligned lens by representing a model's behavior through semantically…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ehud Gordon , Meir Yossef Levi , Guy Gilboa

We propose a multiple imputation method based on principal component analysis (PCA) to deal with incomplete continuous data. To reflect the uncertainty of the parameters from one imputation to the next, we use a Bayesian treatment of the…

Methodology · Statistics 2015-08-20 Vincent Audigier , François Husson , Julie Josse

In this paper, we address the problem of hidden common variables discovery from multimodal data sets of nonlinear high-dimensional observations. We present a metric based on local applications of canonical correlation analysis (CCA) and…

Machine Learning · Computer Science 2017-07-12 Or Yair , Ronen Talmon

Sparse Canonical Correlation Analysis (SCCA) is a fundamental statistical tool for identifying linear relationships in high-dimensional, multi-view data. While minimax theory establishes an optimal sample complexity scaling additively with…

Signal Processing · Electrical Eng. & Systems 2026-04-21 Mengchu Xu , Jian Wang , Yonina C. Eldar

For over a century canonical correlations, variables, and related concepts have been studied across various fields, with contributions dating back to Jordan [1875] and Hotelling [1936]. This text surveys the evolution of canonical…

Methodology · Statistics 2025-11-07 Anna Bykhovskaya , Vadim Gorin