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Brain tissue segmentation from multimodal MRI is a key building block of many neuroimaging analysis pipelines. Established tissue segmentation approaches have, however, not been developed to cope with large anatomical changes resulting from…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Reuben Dorent , Thomas Booth , Wenqi Li , Carole H. Sudre , Sina Kafiabadi , Jorge Cardoso , Sebastien Ourselin , Tom Vercauteren

In this paper, we propose a novel deep learning framework for anatomy segmentation and automatic landmark- ing. Specifically, we focus on the challenging problem of mandible segmentation from cone-beam computed tomography (CBCT) scans and…

Computer Vision and Pattern Recognition · Computer Science 2018-10-10 Neslisah Torosdagli , Denise K. Liberton , Payal Verma , Murat Sincan , Janice S. Lee , Ulas Bagci

In recent years, deep learning has led to impressive results in many fields. In this paper, we introduce a multi-scale artificial neural network for high-dimensional non-linear maps based on the idea of hierarchical nested bases in the fast…

Numerical Analysis · Mathematics 2019-02-27 Yuwei Fan , Jordi Feliu-Faba , Lin Lin , Lexing Ying , Leonardo Zepeda-Nunez

Organs-at-risk (OAR) delineation in computed tomography (CT) is an important step in Radiation Therapy (RT) planning. Recently, deep learning based methods for OAR delineation have been proposed and applied in clinical practice for separate…

Image and Video Processing · Electrical Eng. & Systems 2020-01-14 Shanlin Sun , Yang Liu , Narisu Bai , Hao Tang , Xuming Chen , Qian Huang , Yong Liu , Xiaohui Xie

In deformable registration, the geometric framework - large deformation diffeomorphic metric mapping or LDDMM, in short - has inspired numerous techniques for comparing, deforming, averaging and analyzing shapes or images. Grounded in…

Artificial Intelligence · Computer Science 2022-05-11 Boulbaba Ben Amor , Sylvain Arguillère , Ling Shao

The hippocampus is one of the most studied neuroanatomical structures due to its involvement in attention, learning, and memory as well as its atrophy in ageing, neurological, and psychiatric diseases. Hippocampal shape changes, however,…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Kersten Diers , Hannah Baumeister , Frank Jessen , Emrah Düzel , David Berron , Martin Reuter

Autism spectrum disorder (ASD) has been associated with structural alterations across cortical and subcortical regions. Quantitative neuroimaging enables large-scale analysis of these neuroanatomical patterns. This project used structural…

Neurons and Cognition · Quantitative Biology 2025-12-30 Ashley Chen

A Hadamard-Hitchcock decomposition of a multidimensional array is a decomposition that expresses the latter as a Hadamard product of several tensor rank decompositions. Such decompositions can encode probability distributions that arise…

Algebraic Geometry · Mathematics 2025-10-30 Alessandro Oneto , Nick Vannieuwenhoven

Anomaly detection and localization in medical imaging remain critical challenges in healthcare. This paper introduces Spatial-MSMA (Multiscale Score Matching Analysis), a novel unsupervised method for anomaly localization in volumetric…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Ahsan Mahmood , Junier Oliva , Martin Styner

Accurate and reliable image segmentation is an essential part of biomedical image analysis. In this paper, we consider the problem of biomedical image segmentation using deep convolutional neural networks. We propose a new end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2018-10-02 Amirhossein Dadashzadeh , Alireza Tavakoli Targhi

The correlation matrix is a central representation of functional brain networks in neuroimaging. Traditional analyses often treat pairwise interactions independently in a Euclidean setting, overlooking the intrinsic geometry of correlation…

Machine Learning · Statistics 2025-04-10 Kisung You , Yelim Lee , Hae-Jeong Park

Medical images, especially volumetric images, are of high resolution and often exceed the capacity of standard desktop GPUs. As a result, most deep learning-based medical image analysis tasks require the input images to be downsampled,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Jianning Li , Antonio Pepe , Christina Gsaxner , Yuan Jin , Jan Egger

Feature attribution methods, or saliency maps, are one of the most popular approaches for explaining the decisions of complex machine learning models such as deep neural networks. In this study, we propose a stochastic optimization approach…

Machine Learning · Statistics 2018-07-17 Kouichi Ikeno , Satoshi Hara

Frequently, population studies feature pyramidally-organized data represented using Hierarchical Bayesian Models (HBM) enriched with plates. These models can become prohibitively large in settings such as neuroimaging, where a sample is…

Machine Learning · Computer Science 2022-03-09 Louis Rouillard , Demian Wassermann

We propose novel randomized optimization methods for high-dimensional convex problems based on restrictions of variables to random subspaces. We consider oblivious and data-adaptive subspaces and study their approximation properties via…

Information Theory · Computer Science 2020-12-15 Jonathan Lacotte , Mert Pilanci

Recent advances in multi-modal AI have demonstrated promising potential for generating the currently expensive spatial transcriptomics (ST) data directly from routine histology images, offering a means to reduce the high cost and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Junchao Zhu , Ruining Deng , Junlin Guo , Tianyuan Yao , Juming Xiong , Chongyu Qu , Mengmeng Yin , Yu Wang , Shilin Zhao , Haichun Yang , Daguang Xu , Yucheng Tang , Yuankai Huo

Locality of compact one-electron orbitals expanded strictly in terms of local subsets of basis functions can be exploited in density functional theory (DFT) to achieve linear growth of computation time with systems size, crucial in…

Computational Physics · Physics 2021-10-01 Yifei Shi , Jessica Karaguesian , Rustam Z. Khaliullin

The deep neural network is a research hotspot for histopathological image analysis, which can improve the efficiency and accuracy of diagnosis for pathologists or be used for disease screening. The whole slide pathological image can reach…

Image and Video Processing · Electrical Eng. & Systems 2022-05-09 Tingting Zheng , Weixing chen , Shuqin Li , Hao Quan , Qun Bai , Tianhang Nan , Song Zheng , Xinghua Gao , Yue Zhao , Xiaoyu Cui

Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…

Computer Vision and Pattern Recognition · Computer Science 2017-09-08 Marc Aubreville , Maximilian Krappmann , Christof Bertram , Robert Klopfleisch , Andreas Maier

Convolutional dictionary learning (CDL) estimates shift invariant basis adapted to multidimensional data. CDL has proven useful for image denoising or inpainting, as well as for pattern discovery on multivariate signals. As estimated…

Machine Learning · Computer Science 2019-01-29 Thomas Moreau , Alexandre Gramfort