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Probabilistic atlas priors have been commonly used to derive adaptive and robust brain MRI segmentation algorithms. Widely-used neuroimage analysis pipelines rely heavily on these techniques, which are often computationally expensive. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Adrian V. Dalca , Evan Yu , Polina Golland , Bruce Fischl , Mert R. Sabuncu , Juan Eugenio Iglesias

Detection and segmentation of the hippocampal structures in volumetric brain images is a challenging problem in the area of medical imaging. In this paper, we propose a two-stage 3D fully convolutional neural network that efficiently…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Dengsheng Chen , Wenxi Liu , You Huang , Tong Tong , Yuanlong Yu

Automated quality assessment of structural brain MRI is an important prerequisite for reliable neuroimaging analysis, but yet remains challenging due to motion artifacts and poor generalization across acquisition sites. Existing approaches…

Image and Video Processing · Electrical Eng. & Systems 2026-03-09 Naveetha Nithianandam , Prabhjot Kaur , Anil Kumar Sao

The intricate morphology of brain vessels poses significant challenges for automatic segmentation models, which usually focus on a single imaging modality. However, accurately treating brain-related conditions requires a comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Francesco Galati , Daniele Falcetta , Rosa Cortese , Ferran Prados , Ninon Burgos , Maria A. Zuluaga

This paper proposes a two-time scale neurodynamic duplex approach to solve distributionally robust geometric joint chance-constrained optimization problems. The probability distributions of the row vectors are not known in advance and…

Neural and Evolutionary Computing · Computer Science 2026-05-07 Ange Valli , Siham Tassouli , Abdel Lisser

Purpose: The goal of this work was to develop a deep network for whole-head segmentation including clinical MRIs with abnormal anatomy, and compile the first public benchmark dataset for this purpose. We collected 98 MRIs with volumetric…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Andrew M Birnbaum , Adam Buchwald , Peter Turkeltaub , Adam Jacks , George Carra , Shreya Kannana , Yu Huang , Abhisheck Datta , Lucas C Parra , Lukas A Hirsch

The Nielsen-Thurston theory of surface diffeomorphisms shows that useful dynamical information can be obtained about a surface diffeomorphism from a finite collection of periodic orbits.In this paper, we extend these results to homoclinic…

Dynamical Systems · Mathematics 2007-05-23 Pieter Collins

Brain pathologies often manifest as partial or complete loss of tissue. The goal of many neuroimaging studies is to capture the location and amount of tissue changes with respect to a clinical variable of interest, such as disease…

Computer Vision and Pattern Recognition · Computer Science 2022-08-12 Samuel Gerber , Marc Niethammer , Ebrahim Ebrahim , Joseph Piven , Stephen R. Dager , Martin Styner , Stephen Aylward , Andinet Enquobahrie

Computational pathology models that use digitized histopathology whole-slide images have the potential to become a cost-effective and scalable alternative to molecular assays for the prediction of genomic biomarkers, a key task in precision…

Quantitative Methods · Quantitative Biology 2026-03-03 Ekaterina Redekop , Eric Zimmermann , Ava P Amini , Alex X Lu , Neil Tenenholtz , James Brian Hall , Lorin Crawford , Kristen A Severson

Volume conductor problems in cerebral electrophysiology and bioimpedance do not have analytical solutions for nontrivial geometries and require a 3D model of the head and its electrical properties for solving the associated PDEs…

Medical Physics · Physics 2021-11-02 Fernando S Moura , Roberto G Beraldo , Leonardo A Ferreira , Samuli Siltanen

Nonparametric estimation of the conditional distribution of a response given high-dimensional features is a challenging problem. It is important to allow not only the mean but also the variance and shape of the response density to change…

Machine Learning · Statistics 2013-12-05 Francesca Petralia , Joshua Vogelstein , David B. Dunson

Hierarchical learning algorithms that gradually approximate a solution to a data-driven optimization problem are essential to decision-making systems, especially under limitations on time and computational resources. In this study, we…

Machine Learning · Computer Science 2023-03-22 Christos Mavridis , John Baras

Multimodal image alignment involves finding spatial correspondences between volumes varying in appearance and structure. Automated alignment methods are often based on local optimization that can be highly sensitive to their initialization.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Johan Öfverstedt , Joakim Lindblad , Nataša Sladoje

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

Tissue texture is known to exhibit a heterogeneous or non-stationary nature, therefore using a single resolution approach for optimum classification might not suffice. A clinical decision support system that exploits the subband textural…

Computer Vision and Pattern Recognition · Computer Science 2015-12-29 Omar S. Al-Kadi

The skeleton of a digital image is a compact representation of its topology, geometry, and scale. It has utility in many computer vision applications, such as image description, segmentation, and registration. However, skeletonization has…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Martin J. Menten , Johannes C. Paetzold , Veronika A. Zimmer , Suprosanna Shit , Ivan Ezhov , Robbie Holland , Monika Probst , Julia A. Schnabel , Daniel Rueckert

We define a stochastic variant of the proximal point algorithm in the general setting of nonlinear (separable) Hadamard spaces for approximating zeros of the mean of a stochastically perturbed monotone vector field and prove its convergence…

Optimization and Control · Mathematics 2025-10-14 Nicholas Pischke

The Hierarchical Mixture of Experts (HME) is a well-known tree-based model for regression and classification, based on soft probabilistic splits. In its original formulation it was trained by maximum likelihood, and is therefore prone to…

Machine Learning · Computer Science 2012-12-12 Christopher M. Bishop , Markus Svensen

We introduce a new algorithm to solve a regularized spatial-spectral image estimation problem. Our approach is based on the linearized alternating directions method of multipliers (LADMM), which is a variation of the popular ADMM algorithm.…

Signal Processing · Electrical Eng. & Systems 2025-02-25 Yunsong Liu , Debdut Mandal , Congyu Liao , Kawin Setsompop , Justin P. Haldar
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