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This paper presents an approach to incorporate mortality shocks into mortality projections produced by a stochastic multi-population mortality model. The proposed model combines a decreasing stochastic mortality trend with a…

Applications · Statistics 2023-12-25 Jens Robben , Katrien Antonio

Windstorms significantly impact the UK, causing extensive damage to property, disrupting society, and potentially resulting in loss of life. Accurate modelling and understanding of such events are essential for effective risk assessment and…

Atmospheric and Oceanic Physics · Physics 2024-09-18 Etron Yee Chun Tsoi

High-frequency mortality data have attracted growing attention, but their use has largely been confined to specific applications rather than general modelling and forecasting. Such data pose new challenges to traditional mortality models…

Applications · Statistics 2026-05-14 Ziting Miao , Han Li , Yuyu Chen

Background: Accurate survival time estimates aid end-of-life medical decision-making. Objectives: Develop an interpretable survival model for elderly residential aged care residents using advanced machine learning. Setting: A major…

Machine Learning · Computer Science 2023-12-11 Teo Susnjak , Elise Griffin

Medical studies for chronic disease are often interested in the relation between longitudinal risk factor profiles and individuals' later life disease outcomes. These profiles may typically be subject to intermediate structural changes due…

Applications · Statistics 2023-08-22 Sandra Keizer , Zhuozhao Zhan , Vasan S. Ramachandran , Edwin R. van den Heuvel

Many economies are challenged by the effects of an ageing population, particularly in sectors where resource capacity planning is critical, such as healthcare. This research addresses the operational challenges of bed and staffing capacity…

Machine Learning · Computer Science 2025-04-25 Elizabeth Williams , Daniel Gartner , Paul Harper

In the field of cardio-thoracic surgery, valve function is monitored over time after surgery. The motivation for our research comes from a study which includes patients who received a human tissue valve in the aortic position. These…

Aging is a multidimensional process where phenotypes change at varying rates. Longitudinal studies of aging typically involve following a cohort of individuals over the course of several years. This design is hindered by cost, attrition,…

Multivariate functional data that are cross-sectionally compositional data are attracting increasing interest in the statistical modeling literature, a major example being trajectories over time of compositions derived from cause-specific…

Methodology · Statistics 2023-11-21 Emanuele Giovanni Depaoli , Marco Stefanucci , Stefano Mazzuco

The prevalence of dementia is set to explode throughout the 21st century. This trend has already started in developed countries and will continue to place heavy pressures on both public health and social care services across the world. No…

Applications · Statistics 2022-04-13 Christopher Drowley , Luke Burns

This paper considers the problem of forecasting mortality rates. A large number of models have already been proposed for this task, but they generally have the disadvantage of either estimating the model in a two-step process, possibly…

Applications · Statistics 2023-05-26 Patrik Andersson , Mathias Lindholm

Complex data features, such as unmodelled censored event times and variables with time-dependent effects, are common in cancer recurrence studies and pose challenges for Bayesian survival modelling. Current methodologies for predictive…

Methodology · Statistics 2026-01-12 Saku Suorsa , Aki Vehtari

Stochastic volatility often implies increasing risks that are difficult to capture given the dynamic nature of real-world applications. We propose using arc length, a mathematical concept, to quantify cumulative variations (the total…

Methodology · Statistics 2022-12-21 Yan Gao , Rodney A. Sparapani , Sanjib Basu

Generalized additive models (GAMs) are flexible non-linear regression models, which can be fitted efficiently using the approximate Bayesian methods provided by the mgcv R package. While the GAM methods provided by mgcv are based on the…

Methodology · Statistics 2020-07-08 Matteo Fasiolo , Simon N. Wood , Margaux Zaffran , Raphaël Nedellec , Yannig Goude

Historical data about disease outcomes can be integrated into the analysis of clinical trials in many ways. We build on existing literature that uses prognostic scores from a predictive model to increase the efficiency of treatment effect…

Methodology · Statistics 2020-12-25 David Walsh , Alejandro Schuler , Diana Hall , Jon Walsh , Charles Fisher

The coronavirus disease 2019 (COVID-19) global pandemic has led many countries to impose unprecedented lockdown measures in order to slow down the outbreak. Questions on whether governments have acted promptly enough, and whether lockdown…

Applications · Statistics 2020-06-04 Zhaozhi Qian , Ahmed M. Alaa , Mihaela van der Schaar

The prevalence of dementia has increased over time as global life expectancy improves and populations age. An individual's risk of developing dementia is influenced by various genetic, lifestyle, and environmental factors, among others.…

Neurons and Cognition · Quantitative Biology 2024-01-12 Srilekha Mamidala

Extreme floods cause casualties, and widespread damage to property and vital civil infrastructure. We here propose a Bayesian approach for predicting extreme floods using the generalized extreme-value (GEV) distribution within gauged and…

Machine learning models that aim to predict dementia onset usually follow the classification methodology ignoring the time until an event happens. This study presents an alternative, using survival analysis within the context of machine…

Machine Learning · Computer Science 2023-06-21 Daniel Stamate , Henry Musto , Olesya Ajnakina , Daniel Stahl

Several epidemiological studies have provided evidence that long-term exposure to fine particulate matter (PM2.5) increases mortality risk. Furthermore, some population characteristics (e.g., age, race, and socioeconomic status) might play…

Methodology · Statistics 2023-11-01 Dafne Zorzetto , Falco J. Bargagli-Stoffi , Antonio Canale , Francesca Dominici
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