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We consider the classic Moran process modeling the spread of genetic mutations, as extended to structured populations by Lieberman et al.\ (Nature, 2005). In this process, individuals are the vertices of a connected graph $G$. Initially,…

Discrete Mathematics · Computer Science 2016-11-08 George Giakkoupis

The fixation probability of a single mutant invading a population of residents is among the most widely-studied quantities in evolutionary dynamics. Amplifiers of natural selection are population structures that increase the fixation…

Populations and Evolution · Quantitative Biology 2020-07-01 Josef Tkadlec , Andreas Pavlogiannis , Krishnendu Chatterjee , Martin A. Nowak

This work studies the generalized Moran process, as introduced by Lieberman et al. [Nature, 433:312-316, 2005]. We introduce the parameterized notions of selective amplifiers and selective suppressors of evolution, i.e. of networks (graphs)…

Data Structures and Algorithms · Computer Science 2018-05-02 George B. Mertzios , Paul G. Spirakis

The Moran process, as studied by Lieberman, Hauert and Nowak, is a randomised algorithm modelling the spread of genetic mutations in populations. The algorithm runs on an underlying graph where individuals correspond to vertices. Initially,…

Probability · Mathematics 2016-05-06 Andreas Galanis , Andreas Göbel , Leslie Ann Goldberg , John Lapinskas , David Richerby

Population structures can be crucial determinants of evolutionary processes. For the Moran process on graphs certain structures suppress selective pressure, while others amplify it (Lieberman et al. 2005 Nature 433 312-316). Evolutionary…

Probability · Mathematics 2014-08-12 Alastair Jamieson-Lane , Christoph Hauert

Populations evolve by accumulating advantageous mutations. Every population has some spatial structure that can be modeled by an underlying network. The network then influences the probability that new advantageous mutations fixate.…

Populations and Evolution · Quantitative Biology 2024-01-29 Jakub Svoboda , Soham Joshi , Josef Tkadlec , Krishnendu Chatterjee

We consider the Moran process in a graph called the "star" and obtain the asymptotic expression for the fixation probability of a single mutant when the size of the graph is large. The expression obtained corrects the previously known…

Populations and Evolution · Quantitative Biology 2016-03-21 Fabio A. C. C. Chalub

We study the Moran process as adapted by Lieberman, Hauert and Nowak. This is a model of an evolving population on a graph or digraph where certain individuals, called "mutants" have fitness r and other individuals, called non-mutants have…

Inspired by recent works on evolutionary graph theory, an area of growing interest in mathematical and computational biology, we present the first known examples of undirected structures acting as suppressors of selection for any fitness…

Populations and Evolution · Quantitative Biology 2017-11-01 Fernando Alcalde Cuesta , Pablo González Sequeiros , Álvaro Lozano Rojo

The Moran process models the spread of genetic mutations through a population. A mutant with relative fitness $r$ is introduced into a population and the system evolves, either reaching fixation (in which every individual is a mutant) or…

Computational Engineering, Finance, and Science · Computer Science 2013-08-01 Josep Diaz , Leslie Ann Goldberg , George B. Mertzios , David Richerby , Maria Serna , Paul G. Spirakis

We analyze evolutionary dynamics on graphs, where the nodes represent individuals of a population. The links of a node describe which other individuals can be displaced by the offspring of the individual on that node. Amplifiers of…

Populations and Evolution · Quantitative Biology 2016-10-27 Laura Hindersin , Arne Traulsen

The stage of evolution is the population of reproducing individuals. The structure of the population is know to affect the dynamics and outcome of evolutionary processes, but analytical results for generic random structures have been…

Populations and Evolution · Quantitative Biology 2014-07-10 Ben Adlam , Martin A. Nowak

The spatial structure of an evolving population affects which mutations become fixed. Some structures amplify selection, increasing the likelihood that beneficial mutations become fixed while deleterious mutations do not. Other structures…

Evolutionary dynamics on graphs can lead to many interesting and counterintuitive findings. We study the Moran process, a discrete time birth-death process, that describes the invasion of a mutant type into a population of wild-type…

Populations and Evolution · Quantitative Biology 2015-04-23 Laura Hindersin , Arne Traulsen

Evolutionary graph theory studies the evolutionary dynamics in a population structure given as a connected graph. Each node of the graph represents an individual of the population, and edges determine how offspring are placed. We consider…

Neural and Evolutionary Computing · Computer Science 2017-06-22 Krishnendu Chatterjee , Rasmus Ibsen-Jensen , Martin A. Nowak

The Moran process is a classic stochastic process that models invasion dynamics on graphs. A single "mutant" (e.g., a new opinion, strain, social trait etc.) invades a population of residents spread over the nodes of a graph. The mutant…

Data Structures and Algorithms · Computer Science 2022-04-26 Joachim Brendborg , Panagiotis Karras , Andreas Pavlogiannis , Asger Ullersted Rasmussen , Josef Tkadlec

The Moran process, as studied by [Lieberman, E., Hauert, C. and Nowak, M. Evolutionary dynamics on graphs. Nature 433, pp. 312-316 (2005)], is a stochastic process modeling the spread of genetic mutations in populations. In this process,…

Populations and Evolution · Quantitative Biology 2021-07-27 Themistoklis Melissourgos , Sotiris Nikoletseas , Christoforos Raptopoulos , Paul Spirakis

The fixation probability of a mutant in the evolutionary dynamics of Moran process is calculated by the Monte-Carlo method on a few families of clique-based graphs. It is shown that the complete suppression of fixation can be realized with…

Populations and Evolution · Quantitative Biology 2018-01-17 Jeong-Ok Choi , Unjong Yu

We consider the Moran process, as generalized by Lieberman, Hauert and Nowak (Nature, 433:312--316, 2005). A population resides on the vertices of a finite, connected, undirected graph and, at each time step, an individual is chosen at…

Computational Complexity · Computer Science 2014-03-21 Josep Díaz , Leslie Ann Goldberg , George B. Mertzios , David Richerby , Maria Serna , Paul G. Spirakis

Computing the rate of evolution in spatially structured populations is difficult. A key quantity is the fixation time of a single mutant with relative reproduction rate $r$ which invades a population of residents. We say that the fixation…

Populations and Evolution · Quantitative Biology 2025-09-18 David A. Brewster , Martin A. Nowak , Josef Tkadlec
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