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Digital pathology has become a standard in the pathology workflow due to its many benefits. These include the level of detail of the whole slide images generated and the potential immediate sharing of cases between hospitals. Recent…

Human-Computer Interaction · Computer Science 2023-07-18 Cristian Camilo Pulgarín-Ospina , Rocío del Amor , Adrián Colomera , Julio Silva-Rodríguez , Valery Naranjo

Deep learning methods have emerged as powerful tools for analyzing histopathological images, but current methods are often specialized for specific domains and software environments, and few open-source options exist for deploying models in…

The proliferation of digital microscopy images, driven by advances in automated whole slide scanning, presents significant opportunities for biomedical research and clinical diagnostics. However, accurately annotating densely packed…

Computer Vision and Pattern Recognition · Computer Science 2025-04-25 Chen Liu , Danqi Liao , Alejandro Parada-Mayorga , Alejandro Ribeiro , Marcello DiStasio , Smita Krishnaswamy

Pathological is crucial to cancer diagnosis. Usually, Pathologists draw their conclusion based on observed cell and tissue structure on histology slides. Rapid development in machine learning, especially deep learning have established…

Image and Video Processing · Electrical Eng. & Systems 2020-01-15 Jiangbo Shi , Zeyu Gao , Haichuan Zhang , Pargorn Puttapirat , Chunbao Wang , Xiangrong Zhang , Chen Li

Image based biomarker discovery typically requires an accurate segmentation of histologic structures (e.g., cell nuclei, tubules, epithelial regions) in digital pathology Whole Slide Images (WSI). Unfortunately, annotating each structure of…

Image and Video Processing · Electrical Eng. & Systems 2021-01-07 Runtian Miao , Robert Toth , Yu Zhou , Anant Madabhushi , Andrew Janowczyk

Recently, there has been a growing interest in research concerning document image analysis and recognition in photographic scenarios. However, the lack of labeled datasets for this emerging challenge poses a significant obstacle, as manual…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Jiaxin Zhang , Bangdong Chen , Hiuyi Cheng , Fengjun Guo , Kai Ding , Lianwen Jin

Inspection of tissues using a light microscope is the primary method of diagnosing many diseases, notably cancer. Highly multiplexed tissue imaging builds on this foundation, enabling the collection of up to 60 channels of molecular…

Annotations are necessary to develop computer vision algorithms for histopathology, but dense annotations at a high resolution are often time-consuming to make. Deep learning models for segmentation are a way to alleviate the process, but…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Eduard Chelebian , Francesco Ciompi , Carolina Wählby

We have seen significant leapfrog advancement in machine learning in recent decades. The central idea of machine learnability lies on constructing learning algorithms that learn from good data. The availability of more data being made…

Computer Vision and Pattern Recognition · Computer Science 2020-08-07 Ng Hui Xian Lynnette , Henry Ng Siong Hock , Nguwi Yok Yen

Deep learning has revolutionized the accurate segmentation of diseases in medical imaging. However, achieving such results requires training with numerous manual voxel annotations. This requirement presents a challenge for whole-body…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Matthias Hadlich , Zdravko Marinov , Moon Kim , Enrico Nasca , Jens Kleesiek , Rainer Stiefelhagen

Recent research in the field of computer vision strongly focuses on deep learning architectures to tackle image processing problems. Deep neural networks are often considered in complex image processing scenarios since traditional computer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Marcel P. Schilling , Luca Rettenberger , Friedrich Münke , Haijun Cui , Anna A. Popova , Pavel A. Levkin , Ralf Mikut , Markus Reischl

One of the challenges facing the adoption of digital pathology workflows for clinical use is the need for automated quality control. As the scanners sometimes determine focus inaccurately, the resultant image blur deteriorates the scanned…

Image and Video Processing · Electrical Eng. & Systems 2018-11-16 Mahdi S. Hosseini , Yueyang Zhang , Lyndon Chan , Konstantinos N. Plataniotis , Jasper A. Z. Brawley-Hayes , Savvas Damaskinos

The deep neural network is a research hotspot for histopathological image analysis, which can improve the efficiency and accuracy of diagnosis for pathologists or be used for disease screening. The whole slide pathological image can reach…

Image and Video Processing · Electrical Eng. & Systems 2022-05-09 Tingting Zheng , Weixing chen , Shuqin Li , Hao Quan , Qun Bai , Tianhang Nan , Song Zheng , Xinghua Gao , Yue Zhao , Xiaoyu Cui

Large annotated datasets have been a key component in the success of deep learning. However, annotating medical images is challenging as it requires expertise and a large budget. In particular, annotating different types of cells in…

Computer Vision and Pattern Recognition · Computer Science 2022-10-12 Cholmin Kang , Chunggi Lee , Heon Song , Minuk Ma , S ergio Pereira

Summary: Advances in 3D live cell microscopy are enabling high-resolution capture of previously unobserved processes. Unleashing the power of modern machine learning methods to fully benefit from these technologies is, however, frustrated…

Human-Computer Interaction · Computer Science 2022-12-12 Adam Platt , E. Josiah Lutton , Edward Offord , Till Bretschneider

Analysis of histopathology slides is a critical step for many diagnoses, and in particular in oncology where it defines the gold standard. In the case of digital histopathological analysis, highly trained pathologists must review vast…

Computer Vision and Pattern Recognition · Computer Science 2020-02-21 Pierre Courtiol , Eric W. Tramel , Marc Sanselme , Gilles Wainrib

In the clinical settings, during digital examination of histopathological slides, the pathologist annotate the slides by marking the rough boundary around the suspected tumour region. The marking or annotation is generally represented as a…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Suvidha Tripathi , Satish Kumar Singh

Datasets in the computer vision academic research community are primarily static. Once a dataset is accepted as a benchmark for a computer vision task, researchers working on this task will not alter it in order to make their results…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Evgeny Toropov , Paola A. Buitrago , Jose M. F. Moura

The problem of artifacts in whole slide image acquisition, prevalent in both clinical workflows and research-oriented settings, necessitates human intervention and re-scanning. Overcoming this challenge requires developing quality control…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Artur Jurgas , Marek Wodzinski , Marina D'Amato , Jeroen van der Laak , Manfredo Atzori , Henning Müller

Deep learning-based object detectors have achieved impressive performance in microscopy imaging, yet their confidence estimates often lack calibration, limiting their reliability for biomedical applications. In this work, we introduce a new…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Francesco Campi , Lucrezia Tondo , Ekin Karabati , Johannes Betge , Marie Piraud
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