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Principal component analysis (PCA) is a widely used unsupervised dimensionality reduction technique in machine learning, applied across various fields such as bioinformatics, computer vision and finance. However, when the response variables…

Applications · Statistics 2025-06-25 Theodosios Papazoglou , Guosheng Yin

Principal Component Analysis (PCA) is a method for estimating a subspace given noisy samples. It is useful in a variety of problems ranging from dimensionality reduction to anomaly detection and the visualization of high dimensional data.…

Statistics Theory · Mathematics 2019-06-14 David Hong , Laura Balzano , Jeffrey A. Fessler

We study high-dimensional sparse estimation tasks in a robust setting where a constant fraction of the dataset is adversarially corrupted. Specifically, we focus on the fundamental problems of robust sparse mean estimation and robust sparse…

Data Structures and Algorithms · Computer Science 2019-11-20 Ilias Diakonikolas , Sushrut Karmalkar , Daniel Kane , Eric Price , Alistair Stewart

Clinical and genomic models are both used to predict breast cancer outcomes, but they are often combined using simple linear rules that do not account for how their risk scores relate, especially at the extremes. Using the METABRIC breast…

Machine Learning · Computer Science 2025-11-25 Agnideep Aich , Sameera Hewage , Md Monzur Murshed

Confounding matters in almost all observational studies that focus on causality. In order to eliminate bias caused by connfounders, oftentimes a substantial number of features need to be collected in the analysis. In this case, large p…

Statistics Theory · Mathematics 2019-12-30 Shinyuu Lee , Yuru Zhu

Unsupervised learning techniques in computer vision often require learning latent representations, such as low-dimensional linear and non-linear subspaces. Noise and outliers in the data can frustrate these approaches by obscuring the…

In this article, we propose a novel variable screening method for linear models named as conditional screening via ordinary least squares projection (COLP). COLP can take advantage of prior knowledge concerning certain active predictors by…

Statistics Theory · Mathematics 2020-02-05 Ning Zhang , Wenxin Jiang , Yuting Lan

Motivation: Machine learning based prediction of compound-protein interactions (CPIs) is important for drug design, screening and repurposing studies and can improve the efficiency and cost-effectiveness of wet lab assays. Despite the…

Quantitative Methods · Quantitative Biology 2022-02-02 Adiba Yaseen , Imran Amin , Naeem Akhter , Asa Ben-Hur , Fayyaz Minhas

A semiparametric copula-based two-part quantile regression framework is developed for the analysis of semicontinuous outcomes characterized by a point mass at zero and a continuous positive component. The proposed approach models the…

Methodology · Statistics 2026-03-17 Guanjie Lyu , Mohamed Belalia , Abdulkadir Hussein

In recent biomedical scientific problems, it is a fundamental issue to integratively cluster a set of objects from multiple sources of datasets. Such problems are mostly encountered in genomics, where data is collected from various sources,…

Effective feature selection is critical for robust and interpretable predictive modeling in medicine, especially when risk factors matter most in extreme patient strata. Many standard selectors emphasize average associations and can miss…

Machine Learning · Statistics 2026-03-05 Agnideep Aich , Md Monzur Murshed , Sameera Hewage , Amanda Mayeaux

In the era of big data, reducing data dimensionality is critical in many areas of science. Widely used Principal Component Analysis (PCA) addresses this problem by computing a low dimensional data embedding that maximally explain variance…

Machine Learning · Statistics 2017-02-24 Soheil Feizi , David Tse

We generalize the closest point method (CPM) to solve surface partial differential equations with general boundary conditions. The proposed extrapolation method provides a unified framework for treating a broad class of inhomogeneous…

Numerical Analysis · Mathematics 2025-11-25 Tony Wong , Colin B. Macdonald , Byungjoon Lee

The unsupervised search for overdense regions in high-dimensional feature spaces, where locally high population densities may be associated with anomalous contaminations to an otherwise more uniform population, is of relevance to…

Data Analysis, Statistics and Probability · Physics 2021-06-11 Tommaso Dorigo , Martina Fumanelli , Chiara Maccani , Marija Mojsovska , Giles C. Strong , Bruno Scarpa

Canonical Correlation Analysis (CCA) is a linear representation learning method that seeks maximally correlated variables in multi-view data. Non-linear CCA extends this notion to a broader family of transformations, which are more powerful…

Machine Learning · Computer Science 2020-02-11 Amichai Painsky , Meir Feder , Naftali Tishby

Herein, we propose a Spearman rank correlation based screening procedure for ultrahigh-dimensional data with censored response case. The proposed method is model-free without specifying any regression forms of predictors or response…

Methodology · Statistics 2022-11-28 Hongni Wang , Jingxin Yan , Xiaodong Yan

Conformal Prediction (CP) is a distribution-free method for constructing prediction sets with marginal finite-sample coverage guarantees, making it a suitable framework for reliable uncertainty quantification in safety-critical object…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Christopher Ries , Moussa Kassem Sbeyti , Nicolas Bianco , Nadja Klein

Estimation of mutual information between random variables has become crucial in a range of fields, from physics to neuroscience to finance. Estimating information accurately over a wide range of conditions relies on the development of…

Methodology · Statistics 2018-11-14 Houman Safaai , Arno Onken , Christopher D. Harvey , Stefano Panzeri

Recently, correlation filter-based trackers have received extensive attention due to their simplicity and superior speed. However, such trackers perform poorly when the target undergoes occlusion, viewpoint change or other challenging…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Yuqi Han , Jinghong Nan , Zengshuo Zhang , Jingjing Wang , Baojun Zhao

Principal component analysis (PCA) is recognised as a quintessential data analysis technique when it comes to describing linear relationships between the features of a dataset. However, the well-known sensitivity of PCA to non-Gaussian…

Machine Learning · Statistics 2019-10-28 Jean P. Chereau , Bruno Scalzo Dees , Danilo P. Mandic
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