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Hyperspectral neutron computed tomography is a tomographic imaging technique in which thousands of wavelength-specific neutron radiographs are measured for each tomographic view. In conventional hyperspectral reconstruction, data from each…
Purpose: To evaluate reliability of upright CT for proton dose calculation and feasibility of a simplified phantom configuration for accelerated routine QA. Methods: A calibration phantom was scanned on an upright CT following consensus…
The determination of relative stopping power (RSP) via proton computed tomography (pCT) of a patient is dependent in part on the knowledge of the incoming proton kinetic energies; the uncertainty in these energies is in turn determined by…
Dual-energy computed tomography (DECT) has shown great potential and promising applications in advanced imaging fields for its capabilities of material decomposition. However, image reconstructions and decompositions under sparse views…
Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…
Fourier Ptychographic Microscopy (FPM) is a computational imaging technique that enables high-resolution imaging over a large field of view. However, its application in the biomedical field has been limited due to the long image…
Ultra sparse-view computed tomography (CT) algorithms can reduce radiation exposure of patients, but those algorithms lack an explicit cycle consistency loss minimization and an explicit log-likelihood maximization in testing. Here, we…
The inversion of linear systems is a fundamental step in many inverse problems. Computational challenges exist when trying to invert large linear systems, where limited computing resources mean that only part of the system can be kept in…
Ptychography is a popular microscopic imaging modality for many scientific discoveries and sets the record for highest image resolution. Unfortunately, the high image resolution for ptychographic reconstruction requires significant amount…
To obtain high-quality Positron emission tomography (PET) images while minimizing radiation exposure, numerous methods have been proposed to reconstruct standard-dose PET (SPET) images from the corresponding low-dose PET (LPET) images.…
Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…
Background: Perfusion computed tomography (CT) images the dynamics of a contrast agent through the body over time, and is one of the highest X-ray dose scans in medical imaging. Recently, a theoretically justified reconstruction algorithm…
Photoacoustic (PA) imaging has been widely applied in both preclinical and clinical applications. With a significantly increasing number of data acquisition channels, fast and high-quality image reconstruction for real-time PA imaging is an…
Fourier ptychography has attracted a wide range of focus for its ability of large space-bandwidth-produce, and quantative phase measurement. It is a typical computational imaging technique which refers to optimizing both the imaging…
Low-Dose computer tomography (LDCT) is an ideal alternative to reduce radiation risk in clinical applications. Although supervised-deep-learning-based reconstruction methods have demonstrated superior performance compared to conventional…
Spectral computed tomography (CT) is an emerging technology capable of providing high chemical specificity, which is crucial for many applications such as detecting threats in luggage. This type of application requires both fast and…
Recent advances in computing such as the massively parallel GPUs (Graphical Processing Units),coupled with the need to store and deliver large quantities of digital data especially images, has brought a number of challenges for Computer…
Direct reconstruction of positron emission tomography (PET) data using deep neural networks is a growing field of research. Initial results are promising, but often the networks are complex, memory utilization inefficient, produce…
As Computed Tomography (CT) scans are an essential medical test, many techniques have been proposed to reconstruct high-quality images using a smaller amount of radiation. One approach is to employ algebraic factorization methods to…
X-Ray based computed tomography (CT) is a well-established technique for determining the three-dimensional structure of an object from its two-dimensional projections. In the past few decades, there have been significant advancements in the…