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Understanding the latent processes from Electronic Medical Records could be a game changer in modern healthcare. However, the processes are complex due to the interaction between at least three dynamic components: the illness, the care and…

Machine Learning · Computer Science 2017-11-23 Phuoc Nguyen , Truyen Tran , Svetha Venkatesh

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, recorded in electronic medical records, are episodic and…

Machine Learning · Statistics 2017-04-12 Trang Pham , Truyen Tran , Dinh Phung , Svetha Venkatesh

Accuracy and interpretability are two dominant features of successful predictive models. Typically, a choice must be made in favor of complex black box models such as recurrent neural networks (RNN) for accuracy versus less accurate but…

Machine Learning · Computer Science 2017-02-28 Edward Choi , Mohammad Taha Bahadori , Joshua A. Kulas , Andy Schuetz , Walter F. Stewart , Jimeng Sun

Today, despite decades of developments in medicine and the growing interest in precision healthcare, vast majority of diagnoses happen once patients begin to show noticeable signs of illness. Early indication and detection of diseases,…

Feature engineering remains a major bottleneck when creating predictive systems from electronic medical records. At present, an important missing element is detecting predictive regular clinical motifs from irregular episodic records. We…

Machine Learning · Statistics 2016-07-27 Phuoc Nguyen , Truyen Tran , Nilmini Wickramasinghe , Svetha Venkatesh

Predicting (1) when the next hospital admission occurs and (2) what will happen in the next admission about a patient by mining electronic health record (EHR) data can provide granular readmission predictions to assist clinical decision…

Machine Learning · Computer Science 2021-02-05 Bhagya Hettige , Weiqing Wang , Yuan-Fang Li , Suong Le , Wray Buntine

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…

Electronic Health Records (EHRs) aggregate diverse information at the patient level, holding a trajectory representative of the evolution of the patient health status throughout time. Although this information provides context and can be…

Machine Learning · Computer Science 2022-09-12 João Figueira Silva , Sérgio Matos

This study introduces a pioneering Dynamic Hypergraph Networks (DHCE) model designed to predict future medical diagnoses from electronic health records with enhanced accuracy. The DHCE model innovates by identifying and differentiating…

Machine Learning · Computer Science 2025-01-07 Wangying Yang , Zitao Zheng , Zhizhong Wu , Bo Zhang , Yuanfang Yang

As hospitals move towards automating and integrating their computing systems, more fine-grained hospital operations data are becoming available. These data include hospital architectural drawings, logs of interactions between patients and…

Machine Learning · Computer Science 2023-03-22 Hankyu Jang , Sulyun Lee , D. M. Hasibul Hasan , Philip M. Polgreen , Sriram V. Pemmaraju , Bijaya Adhikari

Leveraging large historical data in electronic health record (EHR), we developed Doctor AI, a generic predictive model that covers observed medical conditions and medication uses. Doctor AI is a temporal model using recurrent neural…

Machine Learning · Computer Science 2016-09-29 Edward Choi , Mohammad Taha Bahadori , Andy Schuetz , Walter F. Stewart , Jimeng Sun

Predicting the health risks of patients using Electronic Health Records (EHR) has attracted considerable attention in recent years, especially with the development of deep learning techniques. Health risk refers to the probability of the…

Machine Learning · Computer Science 2022-11-15 Yuxi Liu , Shaowen Qin , Antonio Jimeno Yepes , Wei Shao , Zhenhao Zhang , Flora D. Salim

Progress notes are among the most clinically meaningful artifacts in an Electronic Health Record (EHR), offering temporally grounded insights into a patient's evolving condition, treatments, and care decisions. Despite their importance,…

Computation and Language · Computer Science 2025-07-21 Garapati Keerthana , Manik Gupta

Three-dimensional (3D) medical images, such as Computed Tomography (CT) and Magnetic Resonance Imaging (MRI), are essential for clinical applications. However, the need for diverse and comprehensive representations is particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Siwen Wang , Churan Wang , Fei Gao , Lixian Su , Fandong Zhang , Yizhou Wang , Yizhou Yu

Electronic health records (EHRs) are longitudinal records of a patient's interactions with healthcare systems. A patient's EHR data is organized as a three-level hierarchy from top to bottom: patient journey - all the experiences of…

Machine Learning · Computer Science 2020-09-29 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Jing Jiang , Chengqi Zhang

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui

Artificial intelligence (AI) is increasingly integrated into modern healthcare, offering powerful support for clinical decision-making. However, in real-world settings, AI systems may experience performance degradation over time, due to…

Artificial Intelligence · Computer Science 2026-02-05 Hao Guan , David Bates , Li Zhou

Machine learning (ML) models deployed in healthcare systems must face data drawn from continually evolving environments. However, researchers proposing such models typically evaluate them in a time-agnostic manner, splitting datasets…

Machine Learning · Computer Science 2023-07-21 Helen Zhou , Yuwen Chen , Zachary C. Lipton

With the recent availability of Electronic Health Records (EHR) and great opportunities they offer for advancing medical informatics, there has been growing interest in mining EHR for improving quality of care. Disease diagnosis due to its…

Artificial Intelligence · Computer Science 2018-04-24 Anahita Hosseini , Ting Chen , Wenjun Wu , Yizhou Sun , Majid Sarrafzadeh
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