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Recent work has shown that the many-body expansion of the interaction energy can effectively be used to develop analytical representations of global potential energy surfaces (PESs) for water. In this study, the role of short- and…

Materials Science · Physics 2015-09-30 Gregory R. Medders , Andreas W. Gotz , Miguel A. Morales , Francesco Paesani

The MB-pol many-body potential has recently emerged as an accurate molecular model for water simulations from the gas to the condensed phase. In this study, the accuracy of MB-pol is systematically assessed across the three phases of water…

We describe the development of machine-learned potentials of atmospheric gases with flexible monomers for molecular simulations. A recently suggested permutationally invariant polynomial neural network (PIP-NN) approach is utilized to…

Chemical Physics · Physics 2025-04-21 Artem Finenko

The microscopic behavior of water under different conditions and in different environments remains the subject of intense debate. A great number of the controversies arise due to the contradictory predictions obtained within different…

Chemical Physics · Physics 2012-10-29 Gregory R. Medders , Volodymyr Babin , Francesco Paesani

Water's unique hydrogen-bonding network and anomalous properties pose significant challenges for accurately modeling its structural, thermodynamic, and transport behavior across varied conditions. Although machine-learned potentials have…

Chemical Physics · Physics 2025-08-29 Ke Xu , Ting Liang , Nan Xu , Penghua Ying , Shunda Chen , Ning Wei , Jianbin Xu , Zheyong Fan

Most widely used machine learned (ML) potentials for condensed phase applications rely on many-body permutationally invariant polynomial (PIP) or atom-centered neural networks (NN). However, these approaches often lack chemical…

We report a permutationally invariant polynomial (PIP) potential energy surface for the water 4-body interaction. This 12-atom PES is a fit to 2119, symmetry-unique, CCSD(T)-F12a/haTZ (aug-cc-pVTZ basis for 'O' atom and cc-pVTZ basis for…

Chemical Physics · Physics 2021-10-27 Apurba Nandi , Chen Qu , Paul L. Houston , Riccardo Conte , Joel M. Bowman

The combination of neural network potential (NNP) with molecular simulations plays an important role in an efficient and thorough understanding of a molecular system's potential energy surface (PES). However, grasping the interplay between…

Computational Physics · Physics 2021-10-28 Ji Woong Yu , Min Young Ha , Bumjoon Seo , Won Bo Lee

Among the many existing molecular models of water, the MB-pol many-body potential has emerged as a remarkably accurate model, capable of reproducing thermodynamic, structural, and dynamic properties across water's solid, liquid, and vapor…

Mechanistic understanding and rational design of complex chemical systems depend on fast and accurate predictions of electronic structures beyond individual building blocks. However, if the system exceeds hundreds of atoms, first-principles…

Chemical Physics · Physics 2026-04-13 Siqi Chen , Zhiqiang Wang , Yili Shen , Xianqi Deng , Xi Cheng , Cheng-Wei Ju , Jun Yi , Guo Ling , Dieaa Alhmoud , Hui Guan , Zhou Lin

The atomic-scale response of inhomogeneous fluids at interfaces and surrounding solute particles plays a critical role in governing chemical, electrochemical and biological processes at such interfaces. Classical molecular dynamics…

Materials Science · Physics 2023-11-28 Kamron Fazel , Nima Karimitari , Tanooj Shah , Christopher Sutton , Ravishankar Sundararaman

Simulating water from first principles remains a significant computational challenge due to the slow dynamics of the underlying system. Although machine-learned interatomic potentials (MLPs) can accelerate these simulations, they often fail…

Chemical Physics · Physics 2026-01-30 Tobias Hilpert , Georg Kresse

Machine learning interatomic potentials (MLIPs) are an emerging modeling technique that promises to provide electronic structure theory accuracy for a fraction of its cost, however, the transferability of MLIPs is a largely unknown factor.…

Chemical Physics · Physics 2024-02-27 Tristan Maxson , Tibor Szilvasi

Permutationally invariant polynomial (PIP) regression has been used to obtain machine-learned (ML) potential energy surfaces, including analytical gradients, for many molecules and chemical reactions. Recently, the approach has been…

Chemical Physics · Physics 2024-07-30 Paul L. Houston , Chen Qu , Apurba Nandi , Riccardo Conte , Qi Yu , Joel M. Bowman

The Many-Body Expansion (MBE) is a useful tool to simulate condensed phase chemical systems, often avoiding the steep computational cost of usual electronic structure methods. However, it often requires higher than 2-body terms to achieve…

Chemical Physics · Physics 2019-11-21 Srimukh Prasad Veccham , Joonho Lee , Martin Head-Gordon

Machine learning has the potential to revolutionize the field of molecular simulation through the development of efficient and accurate models of interatomic interactions. In particular, neural network models can describe interactions at…

Chemical Physics · Physics 2022-04-06 Ang Gao , Richard C. Remsing

We show how an embedded many-body expansion (EMBE) can be used to calculate accurate \emph{ab initio} energies of water clusters and ice structures using wavefunction-based methods. We use the EMBE described recently by Bygrave \emph{et…

Materials Science · Physics 2015-06-16 M. J. Gillan , D. Alfe , P. J. Bygrave , C. R. Taylor , F. R. Manby

Fragmentation methods such as the many-body expansion (MBE) are a common strategy to model large systems by partitioning energies into a hierarchy of decreasingly significant contributions. The number of fragments required for chemical…

Chemical Physics · Physics 2017-09-13 Kun Yao , John E. Herr , John Parkhill

While there have been many developments in computational probes of both strongly-correlated molecular systems and machine-learning accelerated molecular dynamics, there remains a significant gap in capabilities in simulating accurate…

Chemical Physics · Physics 2025-04-04 Yannic Rath , George H. Booth

Machine learning of multi-dimensional potential energy surfaces, from purely ab initio datasets, has seen substantial progress in the past years. Gaussian processes, a popular regression method, have been very successful at producing…

Chemical Physics · Physics 2023-01-11 Fabio E. A. Albertani , Alex J. W. Thom
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