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This paper presents a method for shaping the transmit pulse of a molecular signal such that the diffusion channel's response is a sharp pulse. The impulse response of a diffusion channel is typically characterised as having an infinitely…

Emerging Technologies · Computer Science 2016-11-17 Siyi Wang , Weisi Guo , Mark D. McDonnell

Neural oscillations are universal phenomena and can be observed at different levels of neural systems, from single neuron to macroscopic brain. The frequency of those oscillations are related to the brain functions. However, little is know…

Neurons and Cognition · Quantitative Biology 2015-07-30 Lianchun Yu , Longfei Wang , Fei Jia , Duojie Jia

Neuronal networks constitute a special class of dynamical systems, as they are formed by individual geometrical components, namely the neurons. In the existing literature, relatively little attention has been given to the influence of…

Neurons and Cognition · Quantitative Biology 2015-05-13 Sebastian Ahnert , Luciano da Fontoura Costa

We analytically analyse the motion of a nonrelativistic charged particle in a cylindrical single capillary. The effective potential for interaction of a charged particle with the inner surface of a capillary is derived as a sum of the…

Accelerator Physics · Physics 2021-09-14 S. B. Dabagov , A. V. Dik

Neural oscillations can enhance feature recognition, modulate interactions between neurons, and improve learning and memory. Simulational studies have shown that coherent oscillations give rise to windows in time during which information…

Neurons and Cognition · Quantitative Biology 2014-10-07 Andrew T. Sornborger , Louis Tao

The flow of ions through permeable channels causes voltage drop in physiological nanodomains such as synapses, dendrites and dendritic spines, and other protrusions. How the voltage changes around channels in these nanodomains has remained…

Soft Condensed Matter · Physics 2025-01-10 Frédéric Paquin-Lefebvre , David Holcman

Currently, biological signaling is envisaged as a combination of activation and movement, triggered by local molecular interactions and molecular diffusion, respectively. However, we here suggest, that other fundamental physical mechanisms…

Biological Physics · Physics 2018-05-22 B. Fichtl , I. Silman , M. F. Schneider

Sensory arrays made of coupled excitable elements can improve both their input sensitivity and dynamic range due to collective non-linear wave properties. This mechanism is studied in a neural network of electrically coupled (e.g. via gap…

Disordered Systems and Neural Networks · Physics 2007-05-23 Mauro Copelli , Antonio C. Roque , Rodrigo F. Oliveira , Osame Kinouchi

We investigate the efficient transmission and processing of weak, subthreshold signals in a realistic neural medium in the presence of different levels of the underlying noise. Assuming Hebbian weights for maximal synaptic conductances --…

Biological Physics · Physics 2015-08-19 Joaquin J. Torres , Irene Elices , J. Marro

This article presents a biological neural network model driven by inhomogeneous Poisson processes accounting for the intrinsic randomness of synapses. The main novelty is the introduction of local interactions: each firing neuron triggers…

Probability · Mathematics 2021-08-17 Maximiliano Altamirano , Roberto Cortez , Matthieu Jonckheere , Lasse Leskelä

We consider a threshold-crossing spiking process as a simple model for the activity within a population of neurons. Assuming that these neurons are driven by a common fluctuating input with Gaussian statistics, we evaluate the…

Neurons and Cognition · Quantitative Biology 2009-06-11 Yoram Burak , Sam Lewallen , Haim Sompolinsky

A closed expression is derived for the probability distribution of the transfer matrix of a particle moving in a one-dimensional system with delta-correlated, weak disorder. The change in the distribution as a function of wire length is…

Mesoscale and Nanoscale Physics · Physics 2016-06-22 Mark Ancliff

Transport of molecules across membrane channels is investigated theoretically using exactly solvable discrete stochastic site-binding models. It is shown that the interaction potential between molecules and the channel has a strong effect…

Soft Condensed Matter · Physics 2009-11-11 Anatoly B. Kolomeisky

Neurons are subject to various kinds of noise. In addition to synaptic noise, the stochastic opening and closing of ion channels represents an intrinsic source of noise that affects the signal processing properties of the neuron. In this…

Neurons and Cognition · Quantitative Biology 2008-11-14 Yong Chen , Lianchun Yu , Shao-Meng Qin

Here we analyze synaptic transmission from an information-theoretic perspective. We derive closed-form expressions for the lower-bounds on the capacity of a simple model of a cortical synapse under two explicit coding paradigms. Under the…

Neurons and Cognition · Quantitative Biology 2007-05-23 A. Manwani , C. Koch

The result of computational operations performed at the single cell level are coded into sequences of action potentials (APs). In the cerebral cortex, due to its columnar organization, large number of neurons are involved in any individual…

Neurons and Cognition · Quantitative Biology 2007-05-23 B. Naundorf , T. Geisel , F. Wolf

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

Electrical signaling in the brain plays a vital role to our existence but at the same time, the fundamental mechanism of this propagation is undeciphered. Notable advancements have been made in the numerical modeling supplementing the…

Neurons and Cognition · Quantitative Biology 2024-11-11 Rahul Gulati , Shiva Rudraraju

We consider a noise driven network of integrate-and-fire neurons. The network evolves as result of the activities of the neurons following spike-timing-dependent plasticity rules. We apply a self-consistent mean-field theory to the system…

Neurons and Cognition · Quantitative Biology 2010-02-05 Chun-Chung Chen , David Jasnow

Fluid-structure interaction (FSI) and wave propagation in engineering structures can cause severe damage to piping systems or fluid machines, inducing serious accidents. In these phenomena, the mechanism of structural damage depends on the…

Fluid Dynamics · Physics 2020-11-11 Tomohisa Kojima , Kazuaki Inaba