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Repeated-measure designs allow comparisons within a group as well as between groups, and are commonly referred to as split-plot designs. While originating in agricultural experiments, they are now widely used in medical research,…

Computation · Statistics 2025-12-22 Paavo Sattler , Nils Hichert

Multivariate analysis-of-variance (MANOVA) is a well established tool to examine multivariate endpoints. While classical approaches depend on restrictive assumptions like normality and homogeneity, there is a recent trend to more general…

Statistics Theory · Mathematics 2022-11-29 Marléne Baumeister , Marc Ditzhaus , Markus Pauly

Psychological research often focuses on examining group differences in a set of numeric variables for which normality is doubtful. Longitudinal studies enable the investigation of developmental trends. For instance, a recent study…

Applications · Statistics 2023-10-05 Ricarda Graf , Marina Zeldovich , Sarah Friedrich

In many experiments in the life sciences, several endpoints are recorded per subject. The analysis of such multivariate data is usually based on MANOVA models assuming multivariate normality and covariance homogeneity. These assumptions,…

Applications · Statistics 2017-12-06 Sarah Friedrich , Markus Pauly

In many life science experiments or medical studies, subjects are repeatedly observed and measurements are collected in factorial designs with multivariate data. The analysis of such multivariate data is typically based on multivariate…

Methodology · Statistics 2023-05-24 Lubna Amro , Frank Konietschke , Markus Pauly

Functional data analysis is becoming increasingly popular to study data from real-valued random functions. Nevertheless, there is a lack of multiple testing procedures for such data. These are particularly important in factorial designs to…

Methodology · Statistics 2024-06-04 Merle Munko , Marc Ditzhaus , Markus Pauly , Łukasz Smaga

Latent Markov (LM) models represent an important class of models for the analysis of longitudinal data (Bartolucci et. al., 2013), especially when response variables are categorical. These models have a great potential of application for…

Computation · Statistics 2015-01-20 Francesco Bartolucci , Alessio Farcomeni , Silvia Pandolfi , Fulvia Pennoni

The subject of this paper is to introduce a novel permutation-based nonparametric approach for the problem of ranking several multivariate populations with respect to both experimental and observation studies to be referred to the most…

Methodology · Statistics 2013-04-22 Livio Corain , Luigi Salmaso

Statistical analyses of directional or angular data have applications in a variety of fields, such as geology, meteorology and bioinformatics. There is substantial literature on descriptive and inferential techniques for univariate angular…

Computation · Statistics 2019-03-19 Saptarshi Chakraborty , Samuel W. K. Wong

Multivariate analysis of variance (MANOVA) is a powerful and versatile method to infer and quantify main and interaction effects in metric multivariate multi-factor data. It is, however, neither robust against change in units nor a…

Statistics Theory · Mathematics 2018-02-13 Dennis Dobler , Sarah Friedrich , Markus Pauly

This contribution presents a guide to the R package multilevLCA, which offers a complete and innovative set of technical tools for the latent class analysis of single-level and multilevel categorical data. We describe the available model…

Computation · Statistics 2024-04-11 Johan Lyrvall , Roberto Di Mari , Zsuzsa Bakk , Jennifer Oser , Jouni Kuha

Multiplicative mixed models can be applied in a wide range of scientific disciplines, since they are relevant in every situation where an interaction between a fixed effect and a random effect is present. Until now, no R package has been…

Computation · Statistics 2018-11-05 Sofie Pødenphant , Kasper Kristensen , Per B. Brockhoff

Many experimental paradigms in neuroscience involve driving the nervous system with periodic sensory stimuli. Neural signals recorded using a variety of techniques will then include phase-locked oscillations at the stimulation frequency.…

Methodology · Statistics 2021-08-30 Daniel H. Baker

The matrixdist R package provides a comprehensive suite of tools for the statistical analysis of matrix distributions, including phase-type, inhomogeneous phase-type, discrete phase-type, and related multivariate distributions. This paper…

Computation · Statistics 2025-03-11 Martin Bladt , Alaric Mueller , Jorge Yslas

Ordinal user-provided ratings across multiple items are frequently encountered in both scientific and commercial applications. Whilst recommender systems are known to do well on these type of data from a predictive point of view, their…

Methodology · Statistics 2025-03-05 Sjoerd Hermes

The prediction interval is gaining prominence in meta-analysis as it enables the assessment of uncertainties in treatment effects and heterogeneity between studies. However, coverage probabilities of the current standard method for…

Methodology · Statistics 2021-10-18 Kengo Nagashima , Hisashi Noma , Toshi A. Furukawa

Integrative analysis of datasets generated by multiple cohorts is a widely-used approach for increasing sample size, precision of population estimators, and generalizability of analysis results in epidemiological studies. However, often…

Partially observed Markov process (POMP) models, also known as hidden Markov models or state space models, are ubiquitous tools for time series analysis. The R package pomp provides a very flexible framework for Monte Carlo statistical…

Methodology · Statistics 2021-05-27 Aaron A. King , Dao Nguyen , Edward L. Ionides

The current statistical procedures implemented in statistical software packages for pooling of diagnostic test accuracy data include hSROC regression and the bivariate random-effects meta-analysis model (BRMA). However, these models do not…

Methodology · Statistics 2016-04-08 Victoria N Nyaga , Marc Arbyn , Marc Aerts

While there exists several inferential methods for analyzing functional data in factorial designs, there is a lack of statistical tests that are valid (i) in general designs, (ii) under non-restrictive assumptions on the data generating…

Methodology · Statistics 2023-06-28 Merle Munko , Marc Ditzhaus , Markus Pauly , Łukasz Smaga , Jin-Ting Zhang
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