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Material losses in metals are a central bottleneck in plasmonics for many applications. Here we propose and theoretically demonstrate that metal losses can be successfully mitigated with dielectric particles on metallic films, giving rise…

Based on modern single molecule techniques, we devise a number of possible experimental setups to probe local properties of DNA such as the presence of DNA-knots, loops or folds, or to obtain information on the DNA-sequence. Similarly, DNA…

Soft Condensed Matter · Physics 2007-05-23 Ralf Metzler , Tobias Ambjoernsson

Quantum sensors based on solid-state spins provide tremendous opportunities in a wide range of fields from basic physics and chemistry to biomedical imaging. However, integrating them into a scanning probe microscope to enable practical,…

Mesoscale and Nanoscale Physics · Physics 2016-01-19 Jean-Philippe Tetienne , Alain Lombard , David A. Simpson , Cameron Ritchie , Jianing Lu , Paul Mulvaney , Lloyd C. L. Hollenberg

The characterization of individual nanoparticles in a liquid constitutes a critical challenge for environmental, material, and biological sciences. To detect nanoparticles, electronic approaches are especially desirable owing to their…

Deterministic placement and dynamic manipulation of individual plasmonic nanoparticles with nanoscale precision feature an important step towards active nanoplasmonic devices with prescribed levels of performance and functionalities at…

Biological Physics · Physics 2018-03-20 Maximilian J. Urban , Chao Zhou , Xiaoyang Duan , Na Liu

Advanced geometrical nanometrology is critical for process control in semiconductor manufacturing, supporting applications in, e.g., photonic integrated circuits, nanoelectronics, and emerging quantum and optoelectronic technologies.…

Single nanoparticle tracking using optical microscopy is a powerful technique with many applications in biology, chemistry and material sciences. Despite significant advances, localising objects with nanometric position accuracy in a…

Molecular imaging refers to a class of noninvasive biomedical imaging techniques with the sensitivity and specificity to image biochemical variations in-vivo. An ideal molecular imaging technique visualizes a biochemical target according to…

Medical Physics · Physics 2013-04-03 Alex Hegyi , Eli Yablonovitch

The use of photonic crystal and negative refractive index materials is known to improve resolution of optical microscopy and lithography devices down to 80 nm level. Here we demonstrate that utilization of well-known digital image recovery…

Optics · Physics 2009-11-11 I. I. Smolyaninov , J. Elliott , G. Wurtz , A. V. Zayats , C. C. Davis

Owing to its capacity for unique (bio)-chemical specificity, microscopy withmid-IR illumination holds tremendous promise for a wide range of biomedical and industrial applications. The primary limitation, however, remains detection; with…

We demonstrate the feasibility of high-quality digital holography of the human retina in real-time with a fast camera and commodity computer hardware. High throughput rendering of digital Fresnel holograms from optically-acquired inline…

Medical Physics · Physics 2020-04-03 Leo Puyo , Loic Bellonnet-Mottet , Antoine Martin , Francois Te , Michel Paques , Michael Atlan

Understanding and manipulating two-dimensional materials for real-world applications remains challenging due to a lack of effective and high-throughput characterization techniques. Soft X-ray time-of-flight photoemission electron microscopy…

Materials Science · Physics 2025-12-22 Aashwin Mishra , Daniel Ratner , Quynh Nguyen

Crystal strain variation imposes significant limitations on many quantum sensing and information applications for solid-state defect qubits in diamond. Thus, precision measurement and control of diamond crystal strain is a key challenge.…

All optical nanothermometry has become a powerful, noninvasive tool for measuring nanoscale temperatures in applications ranging from medicine to nanooptics and solid-state nanodevices. The key features of any candidate nanothermometer are…

Plasmonic nanopores combine nanofluidic confinement with electromagnetic field enhancement, enabling optical interrogation of single molecules in sub-wavelength volumes. Yet, direct optical readout within these metallic geometries has…

The increasing importance of artificial intelligence and machine learning in materials research has created demand for automated, high-throughput characterization techniques capable of rapidly generating large data sets. We describe here a…

Benefitting from the excellent characteristics such as low cytotoxicity, functionalization versatility, and tunable fluorescence, nanodiamonds (NDs) have shown enormous application potentials in the biomedical field. Herein, we proposed,…

The correction of the influence of phase corrugation in the pupil plane is a fundamental issue in achieving high dynamic range imaging. In this paper, we investigate an instrumental setup which consists in applying interferometric…

Astrophysics · Physics 2008-11-26 S. Lacour , E. Thiébaut , G. Perrin

Progress in real-time, simultaneous in vivo detection of multiple neurotransmitters will help accelerate advances in neuroscience research. The need for development of probes capable of stable electrochemical detection of rapid…

Biologically important molecules span a size range from very large biomacromolecules, such as proteins to small metabolite molecules. Consequently, spectroscopic techniques which can detect and characterize the structure of inherently…

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