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The performance of biomolecular molecular dynamics simulations has steadily increased on modern high performance computing resources but acceleration of the analysis of the output trajectories has lagged behind so that analyzing simulations…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-03-31 Mahzad Khoshlessan , Ioannis Paraskevakos , Geoffrey C. Fox , Shantenu Jha , Oliver Beckstein

The Massive Parallel Computing (MPC) model gained popularity during the last decade and it is now seen as the standard model for processing large scale data. One significant shortcoming of the model is that it assumes to work on static…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-05-23 Giuseppe F. Italiano , Silvio Lattanzi , Vahab S. Mirrokni , Nikos Parotsidis

We propose hMDAP, a hybrid framework for large-scale data analytical processing on Spark, to support multi-paradigm process (incl. OLAP, machine learning, and graph analysis etc.) in distributed environments. The framework features a…

Databases · Computer Science 2017-01-17 Xiaowang Zhang , Jiahui Zhang , Zhiyong Feng

Molecular Dynamics (MD) codes predict the fundamental properties of matter by following the trajectories of a collection of interacting model particles. To exploit diverse modern manycore hardware, efficient codes must use all available…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-08-04 William R. Saunders , James Grant , Eike H. Müller

Hybrid workflows combining traditional HPC and novel ML methodologies are transforming scientific computing. This paper presents the architecture and implementation of a scalable runtime system that extends RADICAL-Pilot with service-based…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-18 Andre Merzky , Mikhail Titov , Matteo Turilli , Ozgur Kilic , Tianle Wang , Shantenu Jha

High-performance computing (HPC) is reshaping computational drug discovery by enabling large-scale, time-efficient molecular simulations. In this work, we explore HPC-driven pipelines for Alzheimer's disease drug discovery, focusing on…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-03 Paul Ruiz Alliata , Diana Rubaga , Daniel Kumlin , Alberto Puliga

Dynamic programming is a powerful technique that is, unfortunately, often inherently sequential. That is, there exists no unified method to parallelize algorithms that use dynamic programming. In this paper, we attempt to address this issue…

Data Structures and Algorithms · Computer Science 2018-09-18 MohammadHossein Bateni , Soheil Behnezhad , Mahsa Derakhshan , MohammadTaghi Hajiaghayi , Vahab Mirrokni

Computational chemistry allows researchers to experiment in sillico: by running a computer simulations of a biological or chemical processes of interest. Molecular dynamics with molecular mechanics model of interactions simulates N-body…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-03-03 Jana Pazúriková

Identifying the connected components of a graph, apart from being a fundamental problem with countless applications, is a key primitive for many other algorithms. In this paper, we consider this problem in parallel settings. Particularly,…

Data Structures and Algorithms · Computer Science 2020-03-13 Soheil Behnezhad , Laxman Dhulipala , Hossein Esfandiari , Jakub Łącki , Vahab Mirrokni

The general increase in data size and data sharing motivates the adoption of Big Data strategies in several scientific disciplines. However, while several options are available, no particular guidelines exist for selecting a Big Data…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-04 Mathieu Dugré , Valérie Hayot-Sasson , Tristan Glatard

As dataset sizes increase, data analysis tasks in high performance computing (HPC) are increasingly dependent on sophisticated dataflows and out-of-core methods for efficient system utilization. In addition, as HPC systems grow, memory…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-01 George K. Thiruvathukal , Cameron Christensen , Xiaoyong Jin , François Tessier , Venkatram Vishwanath

Scientific workflows increasingly involve both HPC and machine-learning tasks, combining MPI-based simulations, training, and inference in a single execution. Launchers such as Slurm's srun constrain concurrency and throughput, making them…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-26 Andre Merzky , Mikhail Titov , Matteo Turilli , Shantenu Jha

We explore the trade-offs of performing linear algebra using Apache Spark, compared to traditional C and MPI implementations on HPC platforms. Spark is designed for data analytics on cluster computing platforms with access to local disks…

Quantum-based molecular dynamics (QMD) is a highly accurate and transferable method for material science simulations. However, the time scales and system sizes accessible to QMD are typically limited to picoseconds and a few hundred atoms.…

The Massive Parallel Computation (MPC) model is a theoretical framework for popular parallel and distributed platforms such as MapReduce, Hadoop, or Spark. We consider the task of computing a large matching or small vertex cover in this…

Data Structures and Algorithms · Computer Science 2018-07-24 Krzysztof Onak

Optimizing high-performance power electronic equipment, such as power converters, requires multiscale simulations that incorporate the physics of power semiconductor devices and the dynamics of other circuit components, especially in…

Systems and Control · Electrical Eng. & Systems 2025-01-20 Qingyuan Shi , Chijie Zhuang , Jiapeng Liu , Bo Lin , Xiyu Peng , Dan Wu , Zhicheng Liu , Rong Zeng

When training large machine learning models with many variables or parameters, a single machine is often inadequate since the model may be too large to fit in memory, while training can take a long time even with stochastic updates. A…

Machine Learning · Statistics 2014-06-19 Seunghak Lee , Jin Kyu Kim , Xun Zheng , Qirong Ho , Garth A. Gibson , Eric P. Xing

In the era of big data and cloud computing, large amounts of data are generated from user applications and need to be processed in the datacenter. Data-parallel computing frameworks, such as Apache Spark, are widely used to perform such…

Performance · Computer Science 2018-05-09 Zhengyu Yang , Danlin Jia , Stratis Ioannidis , Ningfang Mi , Bo Sheng

We consider the problem of energy-efficient on-line scheduling for slice-parallel video decoders on multicore systems. We assume that each of the processors are Dynamic Voltage Frequency Scaling (DVFS) enabled such that they can…

Multimedia · Computer Science 2013-06-06 Nicholas Mastronarde , Karim Kanoun , David Atienza , Pascal Frossard , Mihaela van der Schaar

Several methods exist today to accelerate Machine Learning(ML) or Deep-Learning(DL) model performance for training and inference. However, modern techniques that rely on various graph and operator parallelism methodologies rely on search…

Machine Learning · Computer Science 2023-08-23 Srinjoy Das , Lawrence Rauchwerger
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