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One primary technical challenge in photoacoustic microscopy (PAM) is the necessary compromise between spatial resolution and imaging speed. In this study, we propose a novel application of deep learning principles to reconstruct…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Anthony DiSpirito , Daiwei Li , Tri Vu , Maomao Chen , Dong Zhang , Jianwen Luo , Roarke Horstmeyer , Junjie Yao

Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in…

Numerical Analysis · Mathematics 2016-12-21 Simon Arridge , Paul Beard , Marta Betcke , Ben Cox , Nam Huynh , Felix Lucka , Olumide Ogunlade , Edward Zhang

Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the…

Medical Physics · Physics 2013-03-25 Chao Huang , Kun Wang , Liming Nie , Lihong V. Wang , Mark A. Anastasio

Photoacoustic tomography (PAT) is a non-invasive imaging modality that requires recovering the initial data of the wave equation from certain measurements of the solution outside the object. In the standard PAT measurement setup, the used…

Analysis of PDEs · Mathematics 2021-12-07 Linh V. Nguyen , Markus Haltmeier , Richard Kowar , Ngoc Do

Photoacoustic tomography (PAT) is a rapidly-evolving medical imaging modality that combines optical absorption contrast with ultrasound imaging depth. One challenge in PAT is image reconstruction with inadequate acoustic signals due to…

Purpose: Photoacoustic tomography (PAT) is a novel imaging technique that can spatially resolve both morphological and functional tissue properties, such as the vessel topology and tissue oxygenation. While this capacity makes PAT a…

Photoacoustic tomography (PAT) is an emerging technology for biomedical imaging that combines the superiorities of high optical contrast and acoustic penetration. In the PAT system, more photoacoustic (PA) signals are preferred to be…

Instrumentation and Detectors · Physics 2020-12-09 Daohuai Jiang , Hengrong Lan , Yiyun Wang , Feng Gao , Fei Gao

Photoacoustic tomography (PAT) is a hybrid imaging modality that intends to construct high-resolution images of optical properties of heterogeneous media from measured acoustic data generated by the photoacoustic effect. To date, most of…

Numerical Analysis · Mathematics 2019-08-07 Christina Frederick , Kui Ren , Sarah Vallélian

Ultrasonic imaging is being used to obtain information about the acoustic properties of a medium by emitting waves into it and recording their interaction using ultrasonic transducer arrays. The Delay-And-Sum (DAS) algorithm forms images…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 Georgios Pilikos , Lars Horchens , Tristan van Leeuwen , Felix Lucka

Photoacoustic Tomography (PAT) is an emerging biomedical "imaging from coupled physics" technique, in which the image contrast is due to optical absorption, but the information is carried to the surface of the tissue as ultrasound pulses.…

Numerical Analysis · Mathematics 2016-11-03 Simon R. Arridge , Marta M. Betcke , Ben T. Cox , Felix Lucka , Brad E. Treeby

Computational imaging enables compact infrared systems, but deep-learning pipelines that combine image reconstruction and object detection often introduce substantial inference latency. Most existing acceleration strategies compress the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Xuquan Wang , Guishuo Yang , Dapeng Yan , Yujie Xing , Xuanyu Qian , Kai Zhang , Xiong Dun , Jiande Sun , Zhanshan Wang , Xinbin Cheng

Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. When the imaging…

Medical Physics · Physics 2016-11-15 Qiwei Sheng , Kun Wang , Thomas P. Matthews , Jun Xia , Liren Zhu , Lihong V. Wang , Mark A. Anastasio

Photoacoustic tomography (PAT) is an emerging imaging modality that combines the complementary strengths of optical contrast and ultrasonic resolution. A central task is image reconstruction, where measured acoustic signals are used to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Markus Haltmeier , Nadja Gruber , Gyeongha Hwang

Iterative model-based image reconstruction in photoacoustic tomography (PAT) enables principled incorporation of detector physics, object-related priors, and complex acquisition strategies. However, for three-dimensional (3D) imaging…

High-quality imaging in photoacoustic computed tomography (PACT) usually requires a high-channel count system for dense spatial sampling around the object to avoid aliasing-related artefacts. To reduce system complexity, various image…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Bowei Yao , Shilong Cui , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Jingyi Yu , Yuyao Zhang , Xiran Cai

Recent advances in deep learning for tomographic reconstructions have shown great potential to create accurate and high quality images with a considerable speed-up. In this work we present a deep neural network that is specifically designed…

Computer Vision and Pattern Recognition · Computer Science 2020-09-07 Andreas Hauptmann , Felix Lucka , Marta Betcke , Nam Huynh , Jonas Adler , Ben Cox , Paul Beard , Sebastien Ourselin , Simon Arridge

Photoacoustic imaging (PAI) is a promising approach to realize in vivo transcranial cerebral vascular imaging. However, the strong attenuation and distortion of the photoacoustic wave caused by the thick porous skull greatly affect the…

Medical Physics · Physics 2022-08-16 Ya Gao , Wenyi Xu , Yiming Chen , Weiya Xie , Qian Cheng

Photoacoustic (PA) computed tomography (PACT) shows great potentials in various preclinical and clinical applications. A great number of measurements are the premise that obtains a high-quality image, which implies a low imaging rate or a…

Computer Vision and Pattern Recognition · Computer Science 2021-06-01 Hengrong Lan , Juze Zhang , Changchun Yang , Fei Gao

Photoacoustic tomography (PAT) is a promising imaging technique that can visualize the distribution of chromophores within biological tissue. However, the accuracy of PAT imaging is compromised by light fluence (LF), which hinders the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-11 Zhaoyong Liang , Shuangyang Zhang , Zhichao Liang , Zhongxin Mo , Xiaoming Zhang , Yutian Zhong , Wufan Chen , Li Qi

Learning physics-constrained inverse operators-rather than post-processing physics-based reconstructions-is a broadly applicable strategy for problems with expensive forward models. We demonstrate this principle in three-dimensional…