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Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…
We propose a virtual staining methodology based on Generative Adversarial Networks to map histopathology images of breast cancer tissue from H&E stain to PHH3 and vice versa. We use the resulting synthetic images to build Convolutional…
Deep learning models have had a great success in disease classifications using large data pools of skin cancer images or lung X-rays. However, data scarcity has been the roadblock of applying deep learning models directly on prostate…
Bone marrow cytology is required to make a hematological diagnosis, influencing critical clinical decision points in hematology. However, bone marrow cytology is tedious, limited to experienced reference centers and associated with high…
This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…
Accurate segmentation of pheochromocytoma (PCC) in abdominal CT scans is essential for tumor burden estimation, prognosis, and treatment planning. It may also help infer genetic clusters, reducing reliance on expensive testing. This study…
Image classification is widely used to build predictive models for breast cancer diagnosis. Most existing approaches overwhelmingly rely on deep convolutional networks to build such diagnosis pipelines. These model architectures, although…
Breast Ultrasound plays a vital role in cancer diagnosis as a non-invasive approach with cost-effective. In recent years, with the development of deep learning, many CNN-based approaches have been widely researched in both tumor…
Introduction: Nottingham grading system is a major prognostic factor for invasive breast carcinoma (IBC). Its determination requires the evaluation of the mitotic score (MS) which is subject to low intra- and inter-observer reproducibility.…
Imaging biomarkers in neuro-oncology are used for diagnosis, prognosis and treatment response monitoring. Magnetic resonance imaging is typically used throughout the patient pathway because routine structural imaging provides detailed…
Computer assisted diagnosis in digital pathology is becoming ubiquitous as it can provide more efficient and objective healthcare diagnostics. Recent advances have shown that the convolutional Neural Network (CNN) architectures, a…
In practice, histopathological diagnosis of tumor malignancy often requires a human expert to scan through histopathological images at multiple magnification levels, after which a final diagnosis can be accurately determined. However,…
Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…
Data limitation is a significant challenge in applying deep learning to medical images. Recently, the diffusion probabilistic model (DPM) has shown the potential to generate high-quality images by converting Gaussian random noise into…
Accurate nuclei detection and classification are fundamental to computational pathology, yet existing approaches are hindered by reliance on detailed expert annotations and insufficient use of tissue context. We present Tissue-Aware Nuclei…
Endometrial cancer, the fourth most common cancer in females in the United States, with the lifetime risk for developing this disease is approximately 2.8% in women. Precise histologic evaluation and molecular classification of endometrial…
Deep learning has introduced several learning-based methods to recognize breast tumours and presents high applicability in breast cancer diagnostics. It has presented itself as a practical installment in Computer-Aided Diagnostic (CAD)…
Breast cancer is one of the most prevalent cancers worldwide and pathologists are closely involved in establishing a diagnosis. Tools to assist in making a diagnosis are required to manage the increasing workload. In this context,…
Despite recent medical advancements, breast cancer remains one of the most prevalent and deadly diseases among women. Although machine learning-based Computer-Aided Diagnosis (CAD) systems have shown potential to assist radiologists in…
Characterization of breast parenchyma in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a challenging task owing to the complexity of underlying tissue structures. Existing quantitative approaches, like radiomics and deep…