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Model-based material decomposition is a statisticaliterative reconstruction framework where basis material densityimages are estimated directly from spectral CT data. This methoduses a physical model for polyenergetic x-ray transmission…

Medical Physics · Physics 2020-10-06 Matthew Tivnan , Wenying Wang , J. Webster Stayman

Compared with conventional single-energy computed tomography (CT), dual-energy CT (DECT) provides better material differentiation but most DECT imaging systems require dual full-angle projection data at different X-ray spectra. Relaxing the…

Multi-material decomposition (MMD) enables quantitative reconstruction of tissue compositions in the human body, supporting a wide range of clinical applications. However, traditional MMD typically requires spectral CT scanners and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-14 Qing Wu , Hongjiang Wei , Jingyi Yu , S. Kevin Zhou , Yuyao Zhang

Positron emission tomography (PET) is an advanced medical imaging technique that plays a crucial role in non-invasive clinical diagnosis. However, while reducing radiation exposure through low-dose PET scans is beneficial for patient…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Bin Huang , Xubiao Liu , Lei Fang , Qiegen Liu , Bingxuan Li

Dual-energy X-ray Computed Tomography (DECT) constitutes an advanced technology which enables automatic decomposition of materials in clinical images without manual segmentation using the dependency of the X-ray linear attenuation with…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Hang Xu , Alexandre Bousse , Alessandro Perelli

Early and accurate diagnosis and lesion localization of bone infections are crucial for clinical treatment. PET-CT integrates anatomical information from CT with metabolic information from PET, making it an important imaging modality for…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Zonglin Yang , Xiaolei Diao , Jishizhan Chen , Xiaozhuang Man , Wei Kong , Gen Wen , Pengfei Cheng , Daqian Shi

Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Zhuonan He , Yikun Zhang , Yu Guan , Shanzhou Niu , Yi Zhang , Yang Chen , Qiegen Liu

Imaging modalities such as Computed Tomography (CT) and Positron Emission Tomography (PET) are key in cancer detection, inspiring Deep Neural Networks (DNN) models that merge these scans for tumor segmentation. When both CT and PET scans…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Nada Saadi , Numan Saeed , Mohammad Yaqub , Karthik Nandakumar

Computed Tomography (CT) is widely used in engineering and medicine for imaging the interior of objects, patients, or animals. If the employed X-ray source is monoenergetic, image reconstruction essentially means the inversion of a ray…

Optimization and Control · Mathematics 2022-06-08 Georgios Papanikos , Benedikt Wirth

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

The conic bundle implementation of the spectral bundle method for large scale semidefinite programming solves in each iteration a semidefinite quadratic subproblem by an interior point approach. For larger cutting model sizes the limiting…

Optimization and Control · Mathematics 2023-08-25 Christoph Helmberg

We develop a method for sparse image reconstruction from polychromatic computed tomography (CT) measurements under the blind scenario where the material of the inspected object and the incident-energy spectrum are unknown. We obtain a…

Methodology · Statistics 2016-05-17 Renliang Gu , Aleksandar Dogandžić

Iodinated contrast media is essential for dual-energy computed tomography (DECT) angiography. Previous studies show that iodinated contrast media may cause side effects, and the interruption of the supply chain in 2022 led to a severe…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Qing Lyu , Josh Tan , Megan E. Lipford , Chuang Niu , Micheal E. Zapadka , Christopher M. Lack , Jonathan D. Clemente , Christopher T. Whitlow , Ge Wang

Transformers have demonstrated remarkable performance in natural language processing and computer vision. However, existing vision Transformers struggle to learn from limited medical data and are unable to generalize on diverse medical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Yunhe Gao , Mu Zhou , Di Liu , Zhennan Yan , Shaoting Zhang , Dimitris N. Metaxas

Spectral Photon-Counting Computed Tomography (SPCCT) is a promising technology that has shown a number of advantages over conventional X-ray Computed Tomography (CT) in the form of material separation, artefact removal and enhanced image…

Image and Video Processing · Electrical Eng. & Systems 2020-03-10 Dimitris Kamilis , Mario Blatter , Nick Polydorides

Spectral imaging is an umbrella term for energy-resolved x-ray imaging in medicine. The technique makes use of the energy dependence of x-ray attenuation to either increase the contrast-to-noise ratio, or to provide quantitative image data…

Medical Physics · Physics 2021-01-05 Erik Fredenberg

In clinical practice, single-radiotracer positron emission tomography (PET) is commonly used for imaging. Although multi-tracer PET imaging can provide supplementary information of radiotracers that are sensitive to physiological function…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Bin Huang , Feihong Xu , Xinchong Shi , Shan Huang , Binxuan Li , Fei Li , Qiegen Liu

Spectral and grating-based differential phase-contrast X-ray imaging are two emerging technologies that offer additional information compared with conventional attenuation-based X-ray imaging. In the case of spectral imaging,…

Medical Physics · Physics 2020-01-31 Korbinian Mechlem , Thorsten Sellerer , Manuel Viermetz , Julia Herzen , Franz Pfeiffer

Three-dimensional x-ray CT image reconstruction in baggage scanning in security applications is an important research field. The variety of materials to be reconstructed is broader than medical x-ray imaging. Presence of high attenuating…

Computer Vision and Pattern Recognition · Computer Science 2015-08-20 S. Degirmenci , Joseph A. O'Sullivan , David G. Politte

Cancer detection and prognosis relies heavily on medical imaging, particularly CT and PET scans. Deep Neural Networks (DNNs) have shown promise in tumor segmentation by fusing information from these modalities. However, a critical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Numan Saeed , Shahad Hardan , Muhammad Ridzuan , Nada Saadi , Karthik Nandakumar , Mohammad Yaqub