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The translocation of a polymer through a pore in a membrane separating fluids of different viscosities is studied via several computational approaches. Starting with the polymer halfway, we find that as a viscosity difference across the…

Soft Condensed Matter · Physics 2013-04-17 Hendrick W. de Haan , Gary W. Slater

We report optical trapping and transport of nanoparticles in a moving interference pattern in hollow-core photonic crystal fiber at atmospheric pressure, when competition between trapping and drag forces causes the particle velocity to…

We predict streaming current inversion with multivalent counterions in hydrodynamically driven polymer translocation events from a correlation-corrected charge transport theory including charge fluctuations around mean-field electrostatics.…

Soft Condensed Matter · Physics 2015-03-05 Sahin Buyukdagli , Ralf Blossey , T. Ala-Nissila

We investigate theoretically the translocation of structured RNA/DNA molecules through narrow pores which allow single but not double strands to pass. The unzipping of basepaired regions within the molecules presents significant kinetic…

Soft Condensed Matter · Physics 2009-11-10 Ulrich Gerland , Ralf Bundschuh , Terence Hwa

Porous graphene has high mechanical strength and atomic layer thickness, which make it a promising material for material separation and biomolecule sensing. Electrostatic interactions between charges in aqueous solution are a kind of strong…

Chemical Physics · Physics 2016-08-02 Yinghua Qiu , Kun Li , Weiyu Chen , Wei Si , Qiyan Tan , Yunfei Chen

We investigate a model nanopore sensor that is able to detect analyte ions that are present in the electrolyte solution in very small concentrations. The nanopore selectively binds the analyte ions with which the local concentrations of the…

Applied Physics · Physics 2018-12-31 Eszter Mádai , Mónika Valiskó , Dezső Boda

We scrutinize the effect of polyvalent ions on polymer-DNA interactions. We extend a recently developed test charge theory to the case of a stiff polymer interacting with a DNA molecule in an electrolyte mixture. The theory accounts for…

Soft Condensed Matter · Physics 2017-03-08 Sahin Buyukdagli

Understanding confined flows of complex fluids requires simultaneous access to the mechanical behaviour of the liquid and the boundary condition at the interfaces. Here, we use evanescent wave microscopy to investigate near-surface flows of…

Soft Condensed Matter · Physics 2020-12-01 Gabriel Guyard , Alexandre Vilquin , Nicolas Sanson , Frederic Restagno , Joshua D. Mcgraw

We investigate the dynamics of polymer translocation through a nanopore under an externally applied field using the 2D fluctuating bond model with single-segment Monte Carlo moves. We concentrate on the influence of the field strength $E$,…

Soft Condensed Matter · Physics 2011-08-26 Kaifu Luo , Ilkka Huopaniemi , Tapio Ala-Nissila , See-Chen Ying

The manipulation of microparticles using optical forces has led to many applications in the life and physical sciences. To extend optical trapping towards the nano-regime, in this work we demonstrate trapping of single nanoparticles in…

Ion transporters in Nature exhibit a wealth of complex transport properties such as voltage gating, activation, and mechanosensitive behavior. When combined, such processes result in advanced ionic machines achieving active ion transport,…

Soft Condensed Matter · Physics 2020-05-08 Laetitia Jubin , Anthony R. Poggioli , Alessandro Siria , Lydéric Bocquet

Ionic Coulomb blockade in nanopores is a phenomenon that shares some similarities but also differences with its electronic counterpart. Here, we investigate extensively this phenomenon using all-atom molecular dynamics of ionic transport…

Mesoscale and Nanoscale Physics · Physics 2017-12-27 Hiroya Tanaka , Hideo Iizuka , Yuriy V. Pershin , Massimiliano Di Ventra

Brownian dynamics (BD) simulations are used to study the translocation dynamics of a coarse-grained polymer through a cylindrical nanopore. We consider the case of short polymers, with a polymer length, N, in the range N=21-61. The rate of…

Soft Condensed Matter · Physics 2015-06-18 James M. Polson , Taylor Dunn

Understanding the adsorption of water and characterizing the water film formed within nanostructures are essential for advancements in fields such as nanofluidics, water purification, and biosensing devices. In our research, we focus on…

We show that the injection of polymer chains into nanochannels becomes easier as the channel becomes narrower. This counter intuitive result arises because of a decrease in the diffusive time scale of the chains with increasing confinement.…

Soft Condensed Matter · Physics 2012-07-16 Rodrigo Ledesma-Aguilar , Takahiro Sakaue , Julia M. Yeomans

The effect of the microscopic structure of a pore on polymer translocation is studied using Langevin dynamics simulation, and the consequence of introducing patterned stickiness inside the pore is investigated. It is found that the…

Soft Condensed Matter · Physics 2013-02-01 Jack A. Cohen , Abhishek Chaudhuri , Ramin Golestanian

Short nanopores have various applications in biosensing, desalination, and energy conversion. Here, the modulation of charged exterior surfaces on ionic transport is investigated through simulations with sub-200 nm long nanopores under…

Soft Condensed Matter · Physics 2024-02-08 Long Ma , Zhe Liu , Jia Man , Jianyong Li , Zuzanna S. Siwy , Yinghua Qiu

The translocation of biopolymers, such as DNA and proteins, across cellular or nuclear membranes is essential for numerous biological processes. The translocation dynamics are influenced by the properties of the polymers, such as polymer…

Soft Condensed Matter · Physics 2024-07-29 Gokul Upadhyay , Rajeev Kapri , Anil Kumar Dasanna , Abhishek Chaudhuri

We investigate the problem of polymer translocation through a nanopore in the absence of an external driving force. To this end, we use the two-dimensional (2D) fluctuating bond model with single-segment Monte Carlo moves. To overcome the…

Computational Physics · Physics 2012-12-06 Kaifu Luo , Tapio Ala-Nissila , See-chen Ying

Resizable elastomeric nanopores have been used to measure pulses of ionic current caused by carboxylated polystyrene spheres of diameter 200 nm and 800 nm. The nanopores represent a novel technology which enables nanoscale resizing of a…

Mesoscale and Nanoscale Physics · Physics 2010-02-04 Geoff R. Willmott , Lara H. Bauerfeind