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Understanding if and how mutants reach fixation in populations is an important question in evolutionary biology. We study the impact of population growth has on the success of mutants. To systematically understand the effects of growth we…

Populations and Evolution · Quantitative Biology 2017-03-29 Peter Ashcroft , Cassandra E. R. Smith , Matthew Garrod , Tobias Galla

We consider a biological population in which a beneficial mutation is undergoing a selective sweep when a second beneficial mutation arises at a linked locus and we investigate the probability that both mutations will eventually fix in the…

Probability · Mathematics 2008-12-02 Feng Yu , Alison Etheridge , Charles Cuthbertson

Competition between individuals drives the evolution of whole species. Although the fittest individuals survive the longest and produce the most offspring, in some circumstances the resulting species may not be optimally fit. Here, using…

Populations and Evolution · Quantitative Biology 2015-09-24 Tim Rogers , Alan J. McKane

We study the competition between several advantageous mutants in an asexual population (clonal interference) as a function of the time between the appearance of the mutants, their selective advantages, and the rate of deleterious mutations.…

Biological Physics · Physics 2007-05-23 Paulo R. A. Campos , Christoph Adami , Claus O. Wilke

We consider the influence of local noise on a generalized network of populations having positive and negative feedbacks. The population dynamics at the nodes is nonlinear, typically chaotic, and allows cessation of activity if the…

Chaotic Dynamics · Physics 2014-12-03 Anshul Choudhary , Vivek Kohar , Sudeshna sinha

In evolutionary dynamics, a key measure of a mutant trait's success is the probability that it takes over the population given some initial mutant-appearance distribution. This "fixation probability" is difficult to compute in general, as…

Populations and Evolution · Quantitative Biology 2022-02-18 Alex McAvoy , Benjamin Allen

Different strains competing for a common pool of susceptible individuals is a key problem in mathematical epidemiology. To address this problem, we investigate a two-strain model within a Susceptible-Infected-Recovered (SIR) framework.…

Populations and Evolution · Quantitative Biology 2026-04-28 Enrique C. Gabrick , Ana Luiza de Moraes , Ervin K. Lenzi , Iberê L. Caldas

We investigate the evolutionary dynamics in directed and/or weighted networks. We study the fixation probability of a mutant in finite populations in stochastic voter-type dynamics for several update rules. The fixation probability is…

Physics and Society · Physics 2009-03-12 Naoki Masuda , Hisashi Ohtsuki

Rock-paper-scissors games metaphorically model cyclic dominance in ecology and microbiology. In a static environment, these models are characterized by fixation probabilities obeying two different "laws" in large and small well-mixed…

Populations and Evolution · Quantitative Biology 2020-02-26 Robert West , Mauro Mobilia

Cooperative interactions pervade in a broad range of many-body populations, such as ecological communities, social organizations, and economic webs. We investigate the dynamics of a population of two equivalent species A and B that are…

Populations and Evolution · Quantitative Biology 2025-01-14 Jordi Piñero , S. Redner , Ricard Solé

Microbial populations generally evolve in volatile environments, under conditions fluctuating between harsh and mild, e.g. as the result of sudden changes in toxin concentration or nutrient abundance. Environmental variability thus shapes…

Populations and Evolution · Quantitative Biology 2023-12-07 Matthew Asker , Lluís Hernández-Navarro , Alastair M. Rucklidge , Mauro Mobilia

The rate of biological evolution depends on the fixation probability and on the fixation time of new mutants. Intensive research has focused on identifying population structures that augment the fixation probability of advantageous mutants.…

Populations and Evolution · Quantitative Biology 2019-03-11 Josef Tkadlec , Andreas Pavlogiannis , Krishnendu Chatterjee , Martin A. Nowak

One essential ingredient of evolutionary theory is the concept of fitness as a measure for a species' success in its living conditions. Here, we quantify the effect of environmental fluctuations onto fitness by analytical calculations on a…

Populations and Evolution · Quantitative Biology 2015-05-19 Anna Melbinger , Massimo Vergassola

When a collection of phenotypically diverse organisms compete with each other for limited resources, with competition being strongest amongst the most similar, the population can evolve into tightly localised clusters. This process can be…

Populations and Evolution · Quantitative Biology 2012-05-16 Tim Rogers , Alan J. McKane , Axel G. Rossberg

The problem of natural selection in dispersal-structured populations consisting of individuals characterized by different diffusion coefficients is studied. The competition between the organisms is taken into account through the assumption…

Adaptation and Self-Organizing Systems · Physics 2020-05-01 E. Heinsalu , D. Navidad Maeso , M. Patriarca

Two mathematical models of macroevolution are studied. These models have population dynamics at the species level, and mutations and extinction of species are also included. The population dynamics are updated by difference equations with…

Populations and Evolution · Quantitative Biology 2014-04-16 Yohsuke Murase , Takashi Shimada , Nobuyasu Ito , Per Arne Rikvold

Populations are made up of an integer number of individuals and are subject to stochastic birth-death processes whose rates may vary in time. Useful quantities, like the chance of ultimate fixation, satisfy an appropriate difference…

Populations and Evolution · Quantitative Biology 2020-07-22 Jayant Pande , Nadav M. Shnerb

The dynamics of well-mixed biological populations is usually studied by mean-field methods and weak-noise expansions. Similar methods have been applied also in spatially extended problems, relying on the fact that these populations are…

Statistical Mechanics · Physics 2015-03-17 Luca Dall'Asta , Fabio Caccioli , Deborah Beghè

We investigate a model where strong noise in a sub-population creates a metastable state in an otherwise unstable two-population system. The induced metastable state is vortex-like, and its persistence time grows exponentially with the…

Statistical Mechanics · Physics 2013-05-29 Matthew Parker , Alex Kamenev , Baruch Meerson

Competition between species and genotypes is a dominant factor in a variety of ecological and evolutionary processes. Biological dynamics are typically highly stochastic, and therefore, analyzing a competitive system requires accounting for…

Populations and Evolution · Quantitative Biology 2025-01-09 Ori Turkia , Nadav M. Shnerb