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Recordings of electrical brain activity carry information about a person's cognitive health. For recording EEG signals, a very common setting is for a subject to be at rest with its eyes closed. Analysis of these recordings often involve a…

Neurons and Cognition · Quantitative Biology 2018-12-18 Sebastian Mathias Keller , Maxim Samarin , Antonia Meyer , Vitalii Kosak , Ute Gschwandtner , Peter Fuhr , Volker Roth

Objective: A clinical decision support tool that automatically interprets EEGs can reduce time to diagnosis and enhance real-time applications such as ICU monitoring. Clinicians have indicated that a sensitivity of 95% with a specificity…

Electroencephalography (EEG), with its broad range of applications, necessitates models that can generalize effectively across various tasks and datasets. Large EEG Models (LEMs) address this by pretraining encoder-centric architectures on…

Machine Learning · Computer Science 2025-09-29 Chenyu Liu , Yuqiu Deng , Tianyu Liu , Jinan Zhou , Xinliang Zhou , Ziyu Jia , Yi Ding

While analytics of sleep electroencephalography (EEG) holds certain advantages over other methods in clinical applications, high variability across subjects poses a significant challenge when it comes to deploying machine learning models…

Machine Learning · Computer Science 2023-10-05 Manoj Vishwanath , Steven Cao , Nikil Dutt , Amir M. Rahmani , Miranda M. Lim , Hung Cao

Brain connectivity can be estimated through a wide number of analyses applied to electroencephalographic (EEG) data. However, substantial heterogeneity in the implementation of connectivity methods exist. Heterogeneity in conceptualization…

Neurons and Cognition · Quantitative Biology 2021-09-01 Aleksandra Miljevic , Neil W. Bailey , Fidel Vila-Rodriguez , Sally E. Herring , Paul B. Fitzgerald

Classifying EEG data is integral to the performance of Brain Computer Interfaces (BCI) and their applications. However, external noise often obstructs EEG data due to its biological nature and complex data collection process. Especially…

Signal Processing · Electrical Eng. & Systems 2023-04-14 Eric Modesitt , Ruiqi Yang , Qi Liu

We studied how lagged linear regression can be used to detect the physiologic effects of drugs from data in the electronic health record (EHR). We systematically examined the effect of methodological variations ((i) time series…

Methodology · Statistics 2018-01-29 Matthew E. Levine , David J. Albers , George Hripcsak

A key task in clinical EEG interpretation is to classify a recording or session as normal or abnormal. In machine learning approaches to this task, recordings are typically divided into shorter windows for practical reasons, and these…

Machine Learning · Computer Science 2024-01-17 Yixuan Zhu , Luke J. W. Canham , David Western

Clinical EEG interpretation requires reasoning over full EEG sessions and integrating signal patterns with clinical context. Existing EEG foundation models are largely designed for short-window decoding and do not incorporate clinical…

Artificial Intelligence · Computer Science 2026-05-12 Peng Cao , Ali Mirzazadeh , Jong Woo Lee , Aleksandar Videnovic , Dina Katabi

Electroencephalography (EEG) is shown to be a valuable data source for evaluating subjects' mental states. However, the interpretation of multi-modal EEG signals is challenging, as they suffer from poor signal-to-noise-ratio, are highly…

Signal Processing · Electrical Eng. & Systems 2022-04-19 David Bethge , Philipp Hallgarten , Ozan Özdenizci , Ralf Mikut , Albrecht Schmidt , Tobias Grosse-Puppendahl

Objective: Machine learning techniques have been used extensively for 12-lead electrocardiogram (ECG) analysis. For physiological time series, deep learning (DL) superiority to feature engineering (FE) approaches based on domain knowledge…

Machine Learning · Computer Science 2022-07-19 Eran Zvuloni , Jesse Read , Antônio H. Ribeiro , Antonio Luiz P. Ribeiro , Joachim A. Behar

Machine learning (ML) methods have the potential to automate clinical EEG analysis. They can be categorized into feature-based (with handcrafted features), and end-to-end approaches (with learned features). Previous studies on EEG pathology…

Unstructured Electronic Health Record (EHR) data, such as clinical notes, contain clinical contextual observations that are not directly reflected in structured data fields. This additional information can substantially improve model…

Machine Learning · Computer Science 2026-03-25 Zigui Wang , Minghui Sun , Jiang Shu , Matthew M. Engelhard , Lauren Franz , Benjamin A. Goldstein

Estimation of heterogeneous treatment effects is an essential component of precision medicine. Model and algorithm-based methods have been developed within the causal inference framework to achieve valid estimation and inference. Existing…

Methodology · Statistics 2021-05-10 Ruohong Li , Honglang Wang , Wanzhu Tu

The electroencephalographic (EEG) signals provide highly informative data on brain activities and functions. However, their heterogeneity and high dimensionality may represent an obstacle for their interpretation. The introduction of a…

Neural and Evolutionary Computing · Computer Science 2023-10-26 Aurora Saibene , Francesca Gasparini

Recently, practical brain-computer interface is actively carried out, especially, in an ambulatory environment. However, the electroencephalography (EEG) signals are distorted by movement artifacts and electromyography signals when users…

Human-Computer Interaction · Computer Science 2021-03-04 Young-Eun Lee , Seong-Whan Lee

Although cognitive engagement (CE) is crucial for motor learning, it remains underutilized in rehabilitation robots, partly because its assessment currently relies on subjective and gross measurements taken intermittently. Here, we propose…

Robotics · Computer Science 2020-02-20 Neelesh Kumar , Konstantinos P. Michmizos

When estimating heterogeneous treatment effects, missing outcome data can complicate treatment effect estimation, causing certain subgroups of the population to be poorly represented. In this work, we discuss this commonly overlooked…

Machine Learning · Statistics 2025-04-15 Matthew Pryce , Karla Diaz-Ordaz , Ruth H. Keogh , Stijn Vansteelandt

Electroencephalography (EEG)-based emotion recognition plays a critical role in affective computing and emerging decision-support systems, yet remains challenging due to high-dimensional, noisy, and subject-dependent signals. This study…

Machine Learning · Computer Science 2026-02-09 S M Rakib UI Karim , Wenyi Lu , Diponkor Bala , Rownak Ara Rasul , Sean Goggins

Datasets in sleep science present challenges for machine learning algorithms due to differences in recording setups across clinics. We investigate two deep transfer learning strategies for overcoming the channel mismatch problem for cases…

Computer Vision and Pattern Recognition · Computer Science 2020-09-02 Alexander Neergaard Olesen , Poul Jennum , Emmanuel Mignot , Helge B. D. Sorensen