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Brain activity is characterized by brain-wide spatiotemporal patterns which emerge from synapse-mediated interactions between individual neurons. Calcium imaging provides access to in vivo recordings of whole-brain activity at single-neuron…

Neurons and Cognition · Quantitative Biology 2023-09-13 Richard E. Rosch , Dominic R. W. Burrows , Christopher W. Lynn , Arian Ashourvan

We explore the connection between deep learning and information theory through the paradigm of diffusion models. A diffusion model converts noise into structured data by reinstating, imperfectly, information that is erased when data was…

Machine Learning · Computer Science 2025-11-04 Akhil Premkumar

Despite their widespread use, the mechanisms by which large language models (LLMs) represent and regulate uncertainty in next-token predictions remain largely unexplored. This study investigates two critical components believed to influence…

Machine Learning · Computer Science 2024-11-11 Alessandro Stolfo , Ben Wu , Wes Gurnee , Yonatan Belinkov , Xingyi Song , Mrinmaya Sachan , Neel Nanda

Understanding the structural complexity and predictability of complex networks is a central challenge in network science. Although recent studies have revealed a relationship between compression-based entropy and link prediction…

Social and Information Networks · Computer Science 2025-10-14 Sebastián Brzovic , Cristóbal Rojas , Andrés Abeliuk

Creating a quantitative theory for the cortex presents challenges and raises questions. What are the significant scales--micro, meso, or macroscopic? What are the interactions--pairwise, higher order, or mean-field? And what control…

Neurons and Cognition · Quantitative Biology 2025-05-29 Nima Dehghani

The science of cities is a relatively new and interdisciplinary topic. It borrows techniques from agent-based modeling, stochastic processes, and partial differential equations. However, how the cities rise and fall, how they evolve, and…

Physics and Society · Physics 2023-04-28 Simone Daniotti , Bernardo Monechi , Enrico Ubaldi

Sleep stage classification is a widely discussed topic, due to its importance in the diagnosis of sleep disorders, e.g. insomnia. Analysis of the brain activity during sleep is necessary to gain further insight into the processing that…

Signal Processing · Electrical Eng. & Systems 2024-10-08 Alexander Edthofer , Iris Feldhammer , Thomas Fenzl , Andreas Körner , Matthias Kreuzer

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neurons and Cognition · Quantitative Biology 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

The repertoire of neural activity patterns that a cortical network can produce constrains the network's ability to transfer and process information. Here, we measured activity patterns obtained from multi-site local field potential (LFP)…

Neurons and Cognition · Quantitative Biology 2010-12-17 Woodrow L. Shew , Hongdian Yang , Shan Yu , Rajarshi Roy , Dietmar Plenz

In the past decade, the cell-type specific connectivity and activity of local cortical networks have been characterized experimentally to some detail. In parallel, modeling has been established as a tool to relate network structure to…

Neurons and Cognition · Quantitative Biology 2011-06-29 Tobias C. Potjans , Markus Diesmann

The availability of large-scale neuronal population datasets necessitates new methods to model population dynamics and extract interpretable, scientifically translatable insights. Existing deep learning methods often overlook the biological…

Neurons and Cognition · Quantitative Biology 2024-11-14 Parsa Delavari , Ipek Oruc , Timothy H Murphy

Although instantaneous interactions are unphysical, a large variety of maximum entropy statistical inference methods match the model-inferred and the empirically-measured equal-time correlation functions. Focusing on collective motion of…

This article is devoted to the theoretical and numerical analysis of a network of excitatory and inhibitory neurons of Hodgkin-Huxley (HH) type, for which the topology is inspired by that of a single local layer of visual cortex V1. Our…

Neurons and Cognition · Quantitative Biology 2021-08-13 M. Maama , B. Ambrosio , M. A. Aziz-Alaoui , S. M. Mintchev

Encoding and decoding models are widely used in systems, cognitive, and computational neuroscience to make sense of brain-activity data. However, the interpretation of their results requires care. Decoding models can help reveal whether…

Neurons and Cognition · Quantitative Biology 2019-04-29 Nikolaus Kriegeskorte , Pamela K. Douglas

Recent efforts to understand intermediate representations in deep neural networks have commonly attempted to label individual neurons and combinations of neurons that make up linear directions in the latent space by examining extremal…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Laura O'Mahony , Nikola S. Nikolov , David JP O'Sullivan

Neural mass models are used to simulate cortical dynamics and to explain the electrical and magnetic fields measured using electro- and magnetoencephalography. Simulations evince a complex phase-space structure for these kinds of models;…

Neurons and Cognition · Quantitative Biology 2022-08-25 Gerald Cooray , Richard Rosch , Karl Friston

The brain is characterized by a strong heterogeneity of inhibitory neurons. We report that spiking neural networks display a resonance to the heterogeneity of inhibitory neurons, with optimal input/output responsiveness occurring for levels…

Neurons and Cognition · Quantitative Biology 2021-09-30 Matteo di Volo , Alain Destexhe

Maximum entropy principle (MEP) offers an effective and unbiased approach to inferring unknown probability distributions when faced with incomplete information, while neural networks provide the flexibility to learn complex distributions…

Machine Learning · Statistics 2024-12-04 Wuyue Yang , Liangrong Peng , Guojie Li , Liu Hong

Large networks of sparsely coupled, excitatory and inhibitory cells occur throughout the brain. A striking feature of these networks is that they are chaotic. How does this chaos manifest in the neural code? Specifically, how variable are…

Neurons and Cognition · Quantitative Biology 2014-02-25 Guillaume Lajoie , Jean-Philippe Thivierge , Eric Shea-Brown

This study investigates the cognitive motor control detection and the underlying neuroregulatory mechanisms during music-assisted simulated driving. Using a dynamic higher-order network model constructed with EEG-based cross-information…

Neurons and Cognition · Quantitative Biology 2026-03-17 Jiajia Li , Fan Li , Jian Song
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