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Mapper, a topological algorithm, is frequently used as an exploratory tool to build a graphical representation of data. This representation can help to gain a better understanding of the intrinsic shape of high-dimensional genomic data and…

Genomics · Quantitative Biology 2023-07-19 Erik J. Amézquita , Farzana Nasrin , Kathleen M. Storey , Masato Yoshizawa

We present a novel coupled two-way clustering approach to gene microarray data analysis. The main idea is to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant…

Biological Physics · Physics 2009-11-06 G. Getz , E. Levine , E. Domany

We present and review Coupled Two Way Clustering, a method designed to mine gene expression data. The method identifies submatrices of the total expression matrix, whose clustering analysis reveals partitions of samples (and genes) into…

Biological Physics · Physics 2007-05-23 Gad Getz , Hilah Gal , Itai Kela , Eytan Domany , Dan A. Notterman

Cluster analysis of biological samples using gene expression measurements is a common task which aids the discovery of heterogeneous biological sub-populations having distinct mRNA profiles. Several model-based clustering algorithms have…

Methodology · Statistics 2012-01-30 Alberto Cozzini , Ajay Jasra , Giovanni Montana

Topological clustering, and its main algorithm ToMATo, is a clustering method from Topological Data Analysis (TDA) which has been applied successfully in several applications during the last few years. This is due to its high versatility,…

Machine Learning · Computer Science 2026-05-15 Ludo Andrianirina , Mathieu Carrière

The Mapper algorithm is a fundamental tool in exploratory topological data analysis for identifying connectivity and topological clustering in data. Derived from the nerve construction, Mapper graphs can contain additional information about…

Computational Geometry · Computer Science 2025-09-30 Halley Fritze

Topological data analysis aims to extract topological quantities from data, which tend to focus on the broader global structure of the data rather than local information. The Mapper method, specifically, generalizes clustering methods to…

Machine Learning · Computer Science 2019-10-22 Jacek Cyranka , Alexander Georges , David Meyer

Cancer subtyping is crucial for understanding the nature of tumors and providing suitable therapy. However, existing labelling methods are medically controversial, and have driven the process of subtyping away from teaching signals.…

Machine Learning · Computer Science 2022-11-15 Zheng Chen , Lingwei Zhu , Ziwei Yang , Takashi Matsubara

Advancements in cytometry technologies have led to a remarkable increase in the number of markers that can be analyzed simultaneously, presenting significant challenges in data analysis. Traditional approaches, such as dimensional reduction…

Quantitative Methods · Quantitative Biology 2025-07-01 Masahiro Ono

The Mapper algorithm is a visualization technique in topological data analysis (TDA) that outputs a graph reflecting the structure of a given dataset. However, the Mapper algorithm requires tuning several parameters in order to generate a…

Machine Learning · Computer Science 2025-02-19 Enrique Alvarado , Robin Belton , Emily Fischer , Kang-Ju Lee , Sourabh Palande , Sarah Percival , Emilie Purvine

Traditional clustering methods are limited when dealing with huge and heterogeneous groups of gene expression data, which motivates the development of bi-clustering methods. Bi-clustering methods are used to mine bi-clusters whose subsets…

Computer Vision and Pattern Recognition · Computer Science 2020-05-13 Kaijie Xu , Witold Pedrycz , Zhiwu Li , Yinghui Quan , Weike Nie

We introduce a graph-theoretic approach to extract clusters and hierarchies in complex data-sets in an unsupervised and deterministic manner, without the use of any prior information. This is achieved by building topologically embedded…

Data Analysis, Statistics and Probability · Physics 2014-02-13 Won-Min Song , T. Di Matteo , Tomaso Aste

Carlsson, Singh and Memoli's TDA mapper takes a point cloud dataset and outputs a graph that depends on several parameter choices. Dey, Memoli, and Wang developed Multiscale Mapper for abstract topological spaces so that parameter choices…

Algebraic Topology · Mathematics 2024-09-27 Wako Bungula , Isabel Darcy

Unsupervised data representation and visualization using tools from topology is an active and growing field of Topological Data Analysis (TDA) and data science. Its most prominent line of work is based on the so-called Mapper graph, which…

Machine Learning · Computer Science 2025-06-04 Ziyad Oulhaj , Mathieu Carrière , Bertrand Michel

Micro-panel data are collected and analysed in many research and industry areas. Cluster analysis of micro-panel data is an unsupervised learning exploratory method identifying subgroup clusters in a data set which include homogeneous…

Machine Learning · Statistics 2018-07-17 Lukas Sobisek , Maria Stachova , Jan Fojtik

Mapper is an algorithm that summarizes the topological information contained in a dataset and provides an insightful visualization. It takes as input a point cloud which is possibly high-dimensional, a filter function on it and an open…

Algebraic Topology · Mathematics 2019-03-12 Bishal Deb , Ankita Sarkar , Nupur Kumari , Akash Rupela , Piyush Gupta , Balaji Krishnamurthy

The Mapper algorithm, a technique within topological data analysis (TDA), constructs a simplified graphical representation of high-dimensional data to uncover its underlying shape and structural patterns. The algorithm has attracted…

General Topology · Mathematics 2025-04-15 Vine Nwabuisi Madukpe , Bright Chukwuma Ugoala , Nur Fariha Syaqina Zulkepli

Data augmentation with \textbf{Mixup} has been proven an effective method to regularize the current deep neural networks. Mixup generates virtual samples and corresponding labels at once through linear interpolation. However, this one-stage…

Machine Learning · Computer Science 2022-06-07 Xiangjin Xie , Yangning Li , Wang Chen , Kai Ouyang , Li Jiang , Haitao Zheng

Data clustering is a common unsupervised learning method frequently used in exploratory data analysis. However, identifying relevant structures in unlabeled, high-dimensional data is nontrivial, requiring iterative experimentation with…

Human-Computer Interaction · Computer Science 2018-11-29 Marco Cavallo , Çağatay Demiralp

Tensors or multiarray data are generalizations of matrices. Tensor clustering has become a very important research topic due to the intrinsically rich structures in real-world multiarray datasets. Subspace clustering based on vectorizing…

Computer Vision and Pattern Recognition · Computer Science 2015-04-30 Yanfeng Sun , Junbin Gao , Xia Hong , Bamdev Mishra , Baocai Yin
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