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Early detection of lung cancer has been proven to decrease mortality significantly. A recent development in computed tomography (CT), spectral CT, can potentially improve diagnostic accuracy, as it yields more information per scan than…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 Linde S. Hesse , Pim A. de Jong , Josien P. W. Pluim , Veronika Cheplygina

Restoring high-quality CT images from low dose CT counterparts is an ill-posed, nonlinear problem to which Deep Learning approaches have been giving superior solutions compared to classical model-based approaches. In this article, a…

Image and Video Processing · Electrical Eng. & Systems 2019-10-16 Shabab Bazrafkan , Vincent Van Nieuwenhove , Jan Sijbers

The unrolling method has been investigated for learning variational models in X-ray computed tomography. However, it has been observed that directly unrolling the regularization model through gradient descent does not produce satisfactory…

Image and Video Processing · Electrical Eng. & Systems 2024-04-19 Yijie Yang , Qifeng Gao , Yuping Duan

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

To obtain high-quality positron emission tomography (PET) images while minimizing radiation exposure, various methods have been proposed for reconstructing standard-dose PET (SPET) images from low-dose PET (LPET) sinograms directly.…

Image and Video Processing · Electrical Eng. & Systems 2023-08-11 Jiaqi Cui , Pinxian Zeng , Xinyi Zeng , Peng Wang , Xi Wu , Jiliu Zhou , Yan Wang , Dinggang Shen

Low-dose Computed Tomography is a common issue in reality. Current reduction, sparse sampling and limited-view scanning can all cause it. Between them, limited-view CT is general in the industry due to inevitable mechanical and physical…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Ken Deng , Chang Sun , Yitong Liu , Hongwen Yang

In this paper, we explore a novel method for tomographic image reconstruction in the field of SPECT imaging. Deep Learning methodologies and more specifically deep convolutional neural networks (CNN) are employed in the new reconstruction…

Machine Learning · Computer Science 2020-10-20 Charalambos Chrysostomou , Loizos Koutsantonis , Christos Lemesios , Costas N. Papanicolas

Utilizing text-only data with an external language model (ELM) in end-to-end RNN-Transducer (RNN-T) for speech recognition is challenging. Recently, a class of methods such as density ratio (DR) and internal language model estimation (ILME)…

Audio and Speech Processing · Electrical Eng. & Systems 2022-08-04 Huahuan Zheng , Keyu An , Zhijian Ou , Chen Huang , Ke Ding , Guanglu Wan

The early diagnosis and screening of glaucoma are important for patients to receive treatment in time and maintain eyesight. Nowadays, deep learning (DL) based models have been successfully used for computer-aided diagnosis (CAD) of…

Image and Video Processing · Electrical Eng. & Systems 2021-08-10 Yiming Bao , Jun Wang , Tong Li , Linyan Wang , Jianwei Xu , Juan Ye , Dahong Qian

Utilizing a low-dose CT approach significantly reduces the radiation exposure for patients, yet it introduces challenges, such as increased noise and artifacts in the resultant images, which can hinder accurate medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Helena Shawn , Thompson Chyrikov , Jacob Lanet , Lam-chi Chen , Jim Zhao , Christina Chajo

Modeling of the collimator-detector response (CDR) in SPECT reconstruction enables improved resolution and accuracy, and is thus important for quantitative imaging applications such as dosimetry. The implementation of CDR modeling, however,…

Objective: There exist several X-ray computed tomography (CT) scanning strategies to reduce a radiation dose, such as (1) sparse-view CT, (2) low-dose CT, and (3) region-of-interest (ROI) CT (called interior tomography). To further reduce…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Yoseob Han , Dufan Wu , Kyungsang Kim , Quanzheng Li

With the development of deep learning, medical image processing has been widely used to assist clinical research. This paper focuses on the denoising problem of low-dose computed tomography using deep learning. Although low-dose computed…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Zhilin Guan , Wei Zhang

Investigation of image reconstruction from data collected over a limited angular range in X-ray CT remains a topic of active research because it may yield insight into the development of imaging workflow of practical significance. This…

Medical Physics · Physics 2021-03-02 Zheng Zhang , Buxin Chen , Dan Xia , Emil Y. Sidky , Xiaochuan Pan

Deep learning (DL) models for disease classification or segmentation from medical images are increasingly trained using transfer learning (TL) from unrelated natural world images. However, shortcomings and utility of TL for specialized…

Machine Learning · Statistics 2021-11-11 Sambuddha Ghosal , Pratik Shah

Dual-energy computed tomography (DECT) enables material-specific imaging through acquisitions at two different X-ray energy spectra. Material decomposition from DECT data is an ill-posed inverse problem that is highly sensitive to noise…

Retinal optical coherence tomography (OCT) images provide crucial insights into the health of the posterior ocular segment. Therefore, the advancement of automated image analysis methods is imperative to equip clinicians and researchers…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Jiahao Wang , Hong Peng , Shengchao Chen , Sufen Ren

Low-dose computed tomography (LDCT) reconstruction is fundamentally challenged by severe noise and compromised data fidelity under reduced radiation exposure. Most existing methods operate either in the image or post-log projection domain,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Bin Huang , Xun Yu , Yikun Zhang , Yi Zhang , Yang Chen , Qiegen Liu

Current mainstream of CT reconstruction methods based on deep learning usually needs to fix the scanning geometry and dose level, which will significantly aggravate the training cost and need more training data for clinical application. In…

Medical Physics · Physics 2020-10-28 Wenjun Xia , Zexin Lu , Yongqiang Huang , Yan Liu , Hu Chen , Jiliu Zhou , Yi Zhang

Deep-learning methods have shown promising performance for low-dose computed tomography (LDCT) reconstruction. However, supervised methods face the problem of lacking labeled data in clinical scenarios, and the CNN-based unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Ran An , Ke Chen , Hongwei Li