Related papers: An Attentive Sequence Model for Adverse Drug Event…
In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent…
Simultaneous administration of multiple drugs can have synergistic or antagonistic effects as one drug can affect activities of other drugs. Synergistic effects lead to improved therapeutic outcomes, whereas, antagonistic effects can be…
The use of multiple drugs accounts for almost 30% of all hospital admission and is the 5th leading cause of death in America. Since over 30% of all adverse drug events (ADEs) are thought to be caused by drug-drug interactions (DDI), better…
Attention-based models have become the leading approach in modeling medical language for Natural Language Processing (NLP) in clinical notes. These models outperform traditional techniques by effectively capturing contextual representations…
We present an analysis of the problem of identifying biological context and associating it with biochemical events in biomedical texts. This constitutes a non-trivial, inter-sentential relation extraction task. We focus on biological…
Relation Extraction (RE) aims to label relations between groups of marked entities in raw text. Most current RE models learn context-aware representations of the target entities that are then used to establish relation between them. This…
Adverse drug events (ADE) are prevalent and costly. Clinical trials are constrained in their ability to identify potential ADEs, motivating the development of spontaneous reporting systems for post-market surveillance. Statistical methods…
With the advancements in Artificial intelligence (AI) and the accumulation of healthrelated big data, it has become increasingly feasible and commonplace to leverage machine learning technologies to analyze clinical and omics metadata to…
In recent years, there has been an increasing number of frameworks developed for biomedical entity and relation extraction. This research effort aims to address the accelerating growth in biomedical publications and the intricate nature of…
Capturing interactions among event arguments is an essential step towards robust event argument extraction (EAE). However, existing efforts in this direction suffer from two limitations: 1) The argument role type information of contextual…
We study the problem of event extraction from text data, which requires both detecting target event types and their arguments. Typically, both the event detection and argument detection subtasks are formulated as supervised sequence…
Recent works in relation extraction (RE) have achieved promising benchmark accuracy; however, our adversarial attack experiments show that these works excessively rely on entities, making their generalization capability questionable. To…
Distantly supervised relation extraction intrinsically suffers from noisy labels due to the strong assumption of distant supervision. Most prior works adopt a selective attention mechanism over sentences in a bag to denoise from wrongly…
Background: Drug-drug interactions (DDIs) refer to processes triggered by the administration of two or more drugs leading to side effects beyond those observed when drugs are administered by themselves. Due to the massive number of possible…
Event extraction (EE), which acquires structural event knowledge from texts, can be divided into two sub-tasks: event type classification and element extraction (namely identifying triggers and arguments under different role patterns). As…
Recurrent Neural Networks (RNNs) have achieved remarkable performance on a range of tasks. A key step to further empowering RNN-based approaches is improving their explainability and interpretability. In this work we present MEME: a model…
Argument structure extraction (ASE) aims to identify the discourse structure of arguments within documents. Previous research has demonstrated that contextual information is crucial for developing an effective ASE model. However, we observe…
Contextual Relation Extraction (CRE) is mainly used for constructing a knowledge graph with a help of ontology. It performs various tasks such as semantic search, query answering, and textual entailment. Relation extraction identifies the…
Adverse drug interactions are a critical concern in pharmacovigilance, as both clinical trials and spontaneous reporting systems often lack the breadth to detect complex drug interactions. This study introduces a computational framework for…
We advance the state of the art in biomolecular interaction extraction with three contributions: (i) We show that deep, Abstract Meaning Representations (AMR) significantly improve the accuracy of a biomolecular interaction extraction…