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Coherent interferometric scattering microscopy (iscat) enables nanoparticle tracking on microsecond timescales and with nanometer precision, and has become a key tool in structural and cellular biophysics. The achievable localization…

Focusing light through dynamically varying heterogeneous media is a sought-after goal with important applications ranging from free-space communication to nano-surgery. The underlying challenge is to control the optical wavefront with a…

Motivated by the importance of optical microscopes to science and engineering, scientists have pondered for centuries how to improve their resolution and the existence of fundamental resolution limits. In recent years, a new class of…

Quantum Physics · Physics 2015-07-28 Mankei Tsang

The last decade has seen numerous efforts to achieve imaging resolution beyond that of the Abbe-Rayleigh diffraction limit. The main direction of research aiming to break this limit seeks to exploit the evanescent components containing fine…

Optics · Physics 2015-05-13 Fu Min Huang , Nikolay I. Zheludev

We experimentally demonstrate quantum enhanced resolution in confocal fluorescence microscopy exploiting the non-classical photon statistics of single nitrogen-vacancy colour centres in diamond. By developing a general model of…

We present an innovative optical imaging system for measuring parameters of a small particle such as a macromolecule or nanoparticle at the quantum limit of sensitivity. In comparison to the conventional confocal interferometric scattering…

Quantum Physics · Physics 2025-07-14 Fabian Müller , Emre Köse , Alfred J. Meixner , Erik Schäffer , Daniel Braun

Quantum metrology promises measurement precision beyond classical limits by exploiting large-scale quantum states, yet realizing this advantage faces two fundamental challenges: the deterministic preparation of non-trivial quantum probes…

We introduce wavefront shaping as a tool for optimizing the sensitivity in nano-optomechanical measurement schemes. We perform multimode output analysis of an optomechanical system consisting of a focused laser beam coupled to the…

A notorious problem in high-resolution biological electron microscopy is radiation damage to the specimen caused by probe electrons. Hence, acquisition of data with minimal number of electrons is of critical importance. Quantum approaches…

Quantum Physics · Physics 2014-03-05 Hiroshi Okamoto , Yukinori Nagatani

Wavefront-shaping is a promising approach for imaging fluorescent targets deep inside scattering tissue despite strong aberrations. It enables focusing an incoming illumination into a single spot inside tissue, as well as correcting the…

Optics · Physics 2024-01-23 Dror Aizik , Anat Levin

Coherent diffractive imaging is unique as the only route for achieving diffraction-limited spatial resolution in the extreme ultraviolet and X-ray regions, limited only by the wavelength of the light. Recently, advances in coherent short…

Integration of metasurfaces with guided mode sources like waveguides have opened new frontiers for on-chip optical integration. However, the state-of-the-art in the field has targeted applications where long focal distances over thousands…

Optics · Physics 2024-03-05 Hrishikesh Iyer , Yurii Vlasov

Astronomers working with faint targets will benefit greatly from improved image quality on current and planned ground-based telescopes. At present, most adaptive optic systems are targeted at the highest resolution with bright guide stars.…

Instrumentation and Methods for Astrophysics · Physics 2020-01-30 Craig Mackay

Focusing light inside scattering media in a freely addressable fashion is challenging, as the wavefront of the scattered light is highly disordered. Recently developed ultrasound-guided wavefront shaping methods are addressing this…

Optics · Physics 2016-01-20 Haowen Ruan , Mooseok Jang , Changhuei Yang

Hyperfine atomic states are among the most promising candidates for qubit encoding in quantum information processing. In atomic systems, hyperfine transitions are typically driven through a two-photon Raman process by a laser field which is…

Lightweight image super-resolution (SR) methods aim at increasing the resolution and restoring the details of an image using a lightweight neural network. However, current lightweight SR methods still suffer from inferior performance and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-04 Jikai Wang , Huan Zheng , Jianbing Shen

Light scattering is the main limitation for optical imaging. However, light can be focused through or inside turbid media by spatially shaping the incident wavefront. Wavefront shaping is ultimately limited by the available photon budget.…

Instrumentation and Detectors · Physics 2021-03-24 Bahareh Mastiani , Ivo M. Vellekoop

We propose a quantum-assisted reconstruction framework for high-resolution tomographic imaging that significantly reduces both qubit requirements and radiation exposure. Conventional quantum reconstruction methods require solving QUBO…

Quantum Physics · Physics 2025-04-30 Hyunju Lee , Kyungtaek Jun

Optical focusing at depths in tissue is the Holy Grail of biomedical optics that may bring revolutionary advancement to the field. Wavefront shaping is a widely accepted approach to solve this problem, but most implementations thus far have…

Applied Physics · Physics 2019-09-04 Yunqi Luo , Suxia Yan , Huanhao Li , Puxiang Lai , Yuanjin Zheng

Wavefront shaping has revolutionized the concepts of optical imaging and focusing. Contrary to what was believed, strong scattering in the optical paths can be exploited in favor of light focusing through turbid media and ultimately improve…