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Automated seizure detection using clinical electroencephalograms is a challenging machine learning problem because the multichannel signal often has an extremely low signal to noise ratio. Events of interest such as seizures are easily…

Machine Learning · Computer Science 2017-12-29 Meysam Golmohammadi , Saeedeh Ziyabari , Vinit Shah , Silvia Lopez de Diego , Iyad Obeid , Joseph Picone

Objective: A clinical decision support tool that automatically interprets EEGs can reduce time to diagnosis and enhance real-time applications such as ICU monitoring. Clinicians have indicated that a sensitivity of 95% with a specificity…

Reliable automatic seizure detection from long-term electroencephalography (EEG) remains an unsolved challenge, as current models often fail to generalize across patients or clinical settings. Manual EEG review still is the standard of…

Signal Processing · Electrical Eng. & Systems 2026-05-20 Jonathan Dan , Amirhossein Shahbazinia , Christodoulos Kechris , David Atienza

Accurate classification of seizure types plays a crucial role in the treatment and disease management of epileptic patients. Epileptic seizure types not only impact the choice of drugs but also the range of activities a patient can safely…

Machine Learning · Computer Science 2020-08-13 Subhrajit Roy , Umar Asif , Jianbin Tang , Stefan Harrer

Machine learning algorithms for seizure detection have shown considerable diagnostic potential, with recent reported accuracies reaching 100%. Yet, only few published algorithms have fully addressed the requirements for successful clinical…

Signal Processing · Electrical Eng. & Systems 2024-08-15 Nina Moutonnet , Steven White , Benjamin P Campbell , Saeid Sanei , Toshihisa Tanaka , Hong Ji , Danilo Mandic , Gregory Scott

Time series event detection methods are evaluated mainly by standard classification metrics that focus solely on detection accuracy. However, inaccuracy in detecting an event can often result from its preceding or delayed effects reflected…

The need for high-quality automated seizure detection algorithms based on electroencephalography (EEG) becomes ever more pressing with the increasing use of ambulatory and long-term EEG monitoring. Heterogeneity in validation methods of…

A major shortcoming of medical practice is the lack of an objective measure of conscious level. Impairment of consciousness is common, e.g. following brain injury and seizures, which can also interfere with sensory processing and volitional…

Neurons and Cognition · Quantitative Biology 2025-12-24 Alexis Pomares Pastor , Ines Ribeiro Violante , Gregory Scott

This paper studies the evaluation of learning-based object detection models in conjunction with model-checking of formal specifications defined on an abstract model of an autonomous system and its environment. In particular, we define two…

Robotics · Computer Science 2022-10-20 Apurva Badithela , Tichakorn Wongpiromsarn , Richard M. Murray

Reliable seizure detection is critical for diagnosing and managing epilepsy, yet clinical workflows remain dependent on time-consuming manual EEG interpretation. While machine learning has shown promise, existing approaches often rely on…

Machine Learning · Computer Science 2025-08-12 Bartlomiej Chybowski , Shima Abdullateef , Hollan Haule , Alfredo Gonzalez-Sulser , Javier Escudero

Machine learning (ML)-based analysis of electroencephalograms (EEGs) is playing an important role in advancing neurological care. However, the difficulties in automatically extracting useful metadata from clinical records hinder the…

Computation and Language · Computer Science 2021-09-14 Samarth Rawal , Yogatheesan Varatharajah

Time series anomaly detection has achieved remarkable progress in recent years. However, evaluation practices have received comparatively less attention, despite their critical importance. Existing metrics exhibit several limitations: (1)…

Machine Learning · Computer Science 2026-03-09 Yuewei Li , Dalin Zhang , Huan Li , Xinyi Gong , Hongjun Chu , Zhaohui Song

Time series anomaly detection is widely used in IoT and cyber-physical systems, yet its evaluation remains challenging due to diverse application objectives and heterogeneous metric assumptions. This study introduces a problem-oriented…

Artificial Intelligence · Computer Science 2026-05-15 Kaixiang Yang , Jiarong Liu , Yupeng Song , Shuanghua Yang , Yujue Zhou

Electroencephalogram (EEG) is an important diagnostic test that physicians use to record brain activity and detect seizures by monitoring the signals. There have been several attempts to detect seizures and abnormalities in EEG signals with…

Machine Learning · Computer Science 2022-03-22 Kwanhyung Lee , Hyewon Jeong , Seyun Kim , Donghwa Yang , Hoon-Chul Kang , Edward Choi

Although a seizure event represents a major deviation from a baseline electroencephalographic signal, there are features of seizure morphology that can be seen in non-epileptic portions of the record. A transient decrease in frequency,…

Signal Processing · Electrical Eng. & Systems 2018-01-09 Eva von Weltin , Tameem Ahsan , Vinit Shah , Dawer Jamshed , Meysam Golmohammadi , Iyad Obeid , Joseph Picone

A major barrier to deploying healthcare AI models is their trustworthiness. One form of trustworthiness is a model's robustness across different subgroups: while existing models may exhibit expert-level performance on aggregate metrics,…

Machine Learning · Computer Science 2023-06-16 Khaled Saab , Siyi Tang , Mohamed Taha , Christopher Lee-Messer , Christopher Ré , Daniel Rubin

Neonatal seizures are a commonly encountered neurological condition. They are the first clinical signs of a serious neurological disorder. Thus, rapid recognition and treatment are necessary to prevent serious fatalities. The use of…

Signal Processing · Electrical Eng. & Systems 2021-12-01 Vishal Nagarajan , Ashwini Muralidharan , Deekshitha Sriraman , Pravin Kumar S

Epilepsy is one of the most prevalent brain disorders that disrupts the lives of millions worldwide. For patients with drug-resistant seizures, there exist implantable devices capable of monitoring neural activity, promptly triggering…

Signal Processing · Electrical Eng. & Systems 2023-10-31 Arman Zarei , Bingzhao Zhu , Mahsa Shoaran

Extensive evaluation of perception systems is crucial for ensuring the safety of intelligent vehicles in complex driving scenarios. Conventional performance metrics such as precision, recall and the F1-score assess the overall detection…

Robotics · Computer Science 2025-12-18 Jörg Gamerdinger , Sven Teufel , Stephan Amann , Lukas Marc Listl , Oliver Bringmann

Scalp electroencephalogram (EEG) signals inherently have a low signal-to-noise ratio due to the way the signal is electrically transduced. Temporal and spatial information must be exploited to achieve accurate detection of seizure events.…

Signal Processing · Electrical Eng. & Systems 2022-02-17 Vahid Khalkhali , Nabila Shawki , Vinit Shah , Meysam Golmohammadi , Iyad Obeid , Joseph Picone
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