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We consider the problem of finding an accurate representation of neuron shapes, extracting sub-cellular features, and classifying neurons based on neuron shapes. In neuroscience research, the skeleton representation is often used as a…

Computer Vision and Pattern Recognition · Computer Science 2022-12-15 Jiaxiang Jiang , Michael Goebel , Cezar Borba , William Smith , B. S. Manjunath

Surface-based analysis of the cerebral cortex is ubiquitous in human neuroimaging with MRI. It is crucial for cortical registration, parcellation, and thickness estimation. Traditionally, these analyses require high-resolution, isotropic…

Image and Video Processing · Electrical Eng. & Systems 2024-09-09 Karthik Gopinath , Douglas N. Greve , Colin Magdamo , Steve Arnold , Sudeshna Das , Oula Puonti , Juan Eugenio Iglesias

When using Convolutional Neural Networks (CNNs) for segmentation of organs and lesions in medical images, the conventional approach is to work with inputs and outputs either as single slice (2D) or whole volumes (3D). One common…

Image and Video Processing · Electrical Eng. & Systems 2020-11-17 Minh H. Vu , Guus Grimbergen , Tufve Nyholm , Tommy Löfstedt

We present the first automated pipeline to create an atlas of in situ hybridization gene expression in the adult marmoset brain in the same stereotaxic space. The pipeline consists of segmentation of gene expression from microscopy images…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Charissa Poon , Muhammad Febrian Rachmadi , Michal Byra , Matthias Schlachter , Binbin Xu , Tomomi Shimogori , Henrik Skibbe

Recent progress in tissue clearing has allowed for the imaging of entire organs at single-cell resolution. These methods produce very large 3D images (several gigabytes for a whole mouse brain). A necessary step in analysing these images is…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Abdullah Nazib , James Galloway , Clinton Fookes , Dimitri Perrin

3D image segmentation is one of the most important and ubiquitous problems in medical image processing. It provides detailed quantitative analysis for accurate disease diagnosis, abnormal detection, and classification. Currently deep…

Computer Vision and Pattern Recognition · Computer Science 2019-06-19 Zhenxi Zhang , Jie Li , Zhusi Zhong , Zhicheng Jiao , Xinbo Gao

Brain segmentation is a fundamental first step in neuroimage analysis. In the case of fetal MRI, it is particularly challenging and important due to the arbitrary orientation of the fetus, organs that surround the fetal head, and…

Explicit neural surface representations allow for exact and efficient extraction of the encoded surface at arbitrary precision, as well as analytic derivation of differential geometric properties such as surface normal and curvature. Such…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Weng Fei Low , Gim Hee Lee

In this paper, we demonstrate the feasibility and performance of deep residual neural networks for volumetric segmentation of irreversibly damaged brain tissue lesions on T1-weighted MRI scans for chronic stroke patients. A total of 239…

Image and Video Processing · Electrical Eng. & Systems 2019-11-27 Naofumi Tomita , Steven Jiang , Matthew E. Maeder , Saeed Hassanpour

Brain morphometry from magnetic resonance imaging (MRI) is a consolidated biomarker for many neurodegenerative diseases. Recent advances in this domain indicate that deep convolutional neural networks can infer morphometric measurements…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Rodrigo Santa Cruz , Léo Lebrat , Pierrick Bourgeat , Vincent Doré , Jason Dowling , Jurgen Fripp , Clinton Fookes , Olivier Salvado

Data-driven machine learning has made significant strides in medical image analysis. However, most existing methods are tailored to specific modalities and assume a particular resolution (often isotropic). This limits their generalizability…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Peirong Liu , Ana Lawry Aguila , Juan E. Iglesias

Medical image analysis tasks often focus on regions or structures located in a particular location within the patient's body. Often large parts of the image may not be of interest for the image analysis task. When using deep-learning based…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Thomas Buddenkotte , Roland Opfer , Julia Krüger , Alessa Hering , Mireia Crispin-Ortuzar

Neuroscientists have devoted significant effort into the creation of standard brain reference atlases for high-throughput registration of anatomical regions of interest. However, variability in brain size and form across individuals poses a…

Computer Vision and Pattern Recognition · Computer Science 2019-06-10 Asim Iqbal , Romesa Khan , Theofanis Karayannis

With the rise of open data, identifiability of individuals based on 3D renderings obtained from routine structural magnetic resonance imaging (MRI) scans of the head has become a growing privacy concern. To protect subject privacy, several…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Nataliia Molchanova , Bénédicte Maréchal , Jean-Philippe Thiran , Tobias Kober , Till Huelnhagen , Jonas Richiardi

The reconstruction of cortical surfaces from brain magnetic resonance imaging (MRI) scans is essential for quantitative analyses of cortical thickness and sulcal morphology. Although traditional and deep learning-based algorithmic pipelines…

Computer Vision and Pattern Recognition · Computer Science 2022-03-21 Fabian Bongratz , Anne-Marie Rickmann , Sebastian Pölsterl , Christian Wachinger

Hippocampus segmentation plays a key role in diagnosing various brain disorders such as Alzheimer's disease, epilepsy, multiple sclerosis, cancer, depression and others. Nowadays, segmentation is still mainly performed manually by…

Image and Video Processing · Electrical Eng. & Systems 2020-05-15 Diedre Carmo , Bruna Silva , Clarissa Yasuda , Letícia Rittner , Roberto Lotufo

For 3D medical image (e.g. CT and MRI) segmentation, the difficulty of segmenting each slice in a clinical case varies greatly. Previous research on volumetric medical image segmentation in a slice-by-slice manner conventionally use the…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Wenxuan Wang , Chen Chen , Jing Wang , Sen Zha , Yan Zhang , Jiangyun Li

Macroscopic spin ensembles possess brain-like features such as non-linearity, plasticity, stochasticity, selfoscillations, and memory effects, and therefore offer opportunities for neuromorphic computing by spintronics devices. Here we…

Disordered Systems and Neural Networks · Physics 2021-01-11 Weichao Yu , Jiang Xiao , Gerrit E. W. Bauer

A central goal of modern magnetic resonance imaging (MRI) is to reduce the time required to produce high-quality images. Efforts have included hardware and software innovations such as parallel imaging, compressed sensing, and deep…

Medical Physics · Physics 2023-03-27 Yihong Xu , Chad W. Farris , Stephan W. Anderson , Xin Zhang , Keith A. Brown

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang