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The discrete fracture model (DFM) has been widely used in the simulation of fluid flow in fractured porous media. Traditional DFM uses the so-called hybrid-dimensional approach to treat fractures explicitly as low-dimensional entries (e.g.…

Numerical Analysis · Mathematics 2021-02-01 Ziyao Xu , Yang Yang

Modeling the evolution of high-dimensional systems from limited snapshot observations at irregular time points poses a significant challenge in quantitative biology and related fields. Traditional approaches often rely on dimensionality…

Machine Learning · Computer Science 2025-08-07 Justin Lee , Behnaz Moradijamei , Heman Shakeri

Model uncertainties and simulation uncertainties occur in mathematical modeling of multiscale complex systems, since some mechanisms or scales are not represented (i.e., "unresolved") due to lack in our understanding of these mechanisms or…

Dynamical Systems · Mathematics 2008-11-25 Jinqiao Duan

The fluid flow and heat transfer problems encountered in industry applications span into different scales and there are different numerical methods for different scales problems. It is not possible to use single scale method to solve…

Computational Engineering, Finance, and Science · Computer Science 2019-08-23 Zheng Li , Mo Yang , Yuwen Zhang

Generalized master equations valid for the third order response of an optically driven multi-level electronic system are derived within Zwanzig projection formalism. Each of three time intervals of the response function is found to require…

Quantum Physics · Physics 2012-01-30 Tomas Mancal , Frantisek Sanda

Multiscale Finite Element Methods (MsFEM) are finite element type approaches dedicated to multiscale problems. They first compute local, oscillatory, problem-dependent basis functions which generate a specific discretization space, and next…

Numerical Analysis · Mathematics 2023-02-08 Rutger A. Biezemans , Claude Le Bris , Frederic Legoll , Alexei Lozinski

In this paper, a methodology for fine scale modeling of large scale structures is proposed, which combines the variational multiscale method, domain decomposition and model order reduction. The influence of the fine scale on the coarse…

Computational Engineering, Finance, and Science · Computer Science 2023-07-06 Philipp Diercks , Karen Veroy , Annika Robens-Radermacher , Jörg F. Unger

In engineering crystal plasticity inelastic mechanisms correspond to tensorial zero-energy valleys in the space of macroscopic strains. The flat nature of such valleys is in contradiction with the fact that plastic slips, mimicking…

Pattern Formation and Solitons · Physics 2024-06-17 N. Perchikov , L. Truskinovsky

In this paper, we describe a new scalable and modular material point method (MPM) code developed for solving large-scale problems in continuum mechanics. The MPM is a hybrid Eulerian-Lagrangian approach, which uses both moving material…

Voxel-based lesion-symptom mapping (VLSM) is an important method for basic and translational human neuroscience research. VLSM leverages modern neuroimaging analysis techniques to build on the classic approach of examining the relationship…

In this work, we propose a modeling procedure for fMRI data analysis using a Bayesian Matrix-Variate Dynamic Linear Model (MVDLM). With this type of model, less complex than the more traditional temporal-spatial models, we are able to take…

Applications · Statistics 2020-01-22 Johnatan Cardona Jiménez , Carlos A. de B. Pereira , Victor Fossaluza

We report an implementation of the lattice Boltzmann method (LBM) to integrate the Bloch-Torrey equation, which describes the evolution of the transverse magnetization vector and the fate of the signal of diffusion magnetic resonance…

Medical Physics · Physics 2020-10-14 Noel M. Naughton , Caroline G. Tennyson , John G. Georgiadis

With a sufficiently fine discretisation, the Lattice Boltzmann Method (LBM) mimics a second order Crank-Nicolson scheme for certain types of balance laws (Farag et al. [2021]). This allows the explicit, highly parallelisable LBM to…

Computational Engineering, Finance, and Science · Computer Science 2023-07-27 Erik Faust , Alexander Schlüter , Henning Müller , Ralf Müller

This paper proposes a virtual element method (VEM) combined with a second-order implicit-explicit scheme based on the scalar auxiliary variable (SAV) method for the incompressible magnetohydrodynamics (MHD) equations. We employ the BDF2…

Numerical Analysis · Mathematics 2024-10-25 Xiaojing Dong , Yunqing Huang , Tianwen Wang

Soft materials (e.g., enveloped viruses, liposomes, membranes and supercooled liquids) simultaneously deform or display collective behaviors, while undergoing atomic scale vibrations and collisions. While the multiple space-time character…

Soft Condensed Matter · Physics 2014-01-03 Peter Ortoleva , Abhishek Singharoy , Stephen Pankavich

Metamodels, or the regression analysis of Monte Carlo simulation results, provide a powerful tool to summarize simulation findings. However, an underutilized approach is the multilevel metamodel (MLMM) that accounts for the dependent data…

Methodology · Statistics 2025-11-21 Joshua Gilbert , Luke Miratrix

Mathematical models are essential for understanding and making predictions about systems arising in nature and engineering. Yet, mathematical models are a simplification of true phenomena, thus making predictions subject to uncertainty.…

Numerical Analysis · Mathematics 2023-03-03 Mark Hobbs , Hussein Rappel , Tim Dodwell

Mixed Models for Repeated Measures (MMRMs) are ubiquitous when analyzing outcomes of clinical trials. However, the linearity of the fixed-effect structure in these models largely restrict their use to estimating treatment effects that are…

Methodology · Statistics 2023-01-23 Lars Lau Raket

A new theoretical model is developed to characterize spatio-temporal mode-locking (ML) in quadratic nonlinear media. The model is based on the two-dimensional nonlinear Schr\"odinger equation with coupling to a mean term (NLSM) and…

Optics · Physics 2020-08-19 Mahmut Bağcı , J. Nathan Kutz

We propose a new data-driven reduced order model (ROM) framework that centers around the hierarchical structure of the variational multiscale (VMS) methodology and utilizes data to increase the ROM accuracy at a modest computational cost.…

Numerical Analysis · Mathematics 2020-10-28 Changhong Mou , Birgul Koc , Omer San , Leo G. Rebholz , Traian Iliescu