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pyspeckit is a toolkit and library for spectroscopic analysis in Python. We describe the pyspeckit package and highlight some of its capabilities, such as interactively fitting a model to data, akin to the historically widely-used splot…

Instrumentation and Methods for Astrophysics · Physics 2022-06-01 Adam Ginsburg , Vlas Sokolov , Miguel de Val-Borro , Erik Rosolowsky , Jaime E. Pineda , Brigitta M. Sipőcz , Jonathan D. Henshaw

The limitations of digital electronics in handling real-time matrix operations for emerging computational tasks - such as artificial intelligence, drug design, and medical imaging - have prompted renewed interest in analog computing.…

We propose the conditional predictive impact (CPI), a consistent and unbiased estimator of the association between one or several features and a given outcome, conditional on a reduced feature set. Building on the knockoff framework of…

Methodology · Statistics 2021-05-14 David S. Watson , Marvin N. Wright

SciPy is an open source scientific computing library for the Python programming language. SciPy 1.0 was released in late 2017, about 16 years after the original version 0.1 release. SciPy has become a de facto standard for leveraging…

The accurate development, assessment, interpretation, and benchmarking of bioinformatics frameworks for analyzing transcriptional regulatory grammars rely on controlled simulations to validate the underlying methods. However, existing…

Genomics · Quantitative Biology 2025-06-27 Katalin Ferenc , Lorenzo Martini , Ieva Rauluseviciute , Geir Kjetil Sandve , Anthony Mathelier

Models used for control design are, to some degree, uncertain. Model uncertainty must be accounted for to ensure the robustness of the closed-loop system. $\mu$-analysis and $\mu$-synthesis methods allow for the analysis and design of…

Systems and Control · Electrical Eng. & Systems 2025-11-19 Timothy Everett Adams , Steven Dahdah , James Richard Forbes

Variational inference (VI) has become the method of choice for fitting many modern probabilistic models. However, practitioners are faced with a fragmented literature that offers a bewildering array of algorithmic options. First, the…

Machine Learning · Statistics 2018-11-29 Thang D. Bui , Cuong V. Nguyen , Siddharth Swaroop , Richard E. Turner

The BumpHunter algorithm is widely used in the search for new particles in High Energy Physics analysis. This algorithm offers the advantage of evaluating the local and global p-values of a localized deviation in the observed data without…

High Energy Physics - Experiment · Physics 2023-10-11 Louis Vaslin , Samuel Calvet , Vincent Barra , Julien Donini

The emergence of data-driven computational materials science offers unprecedented opportunities to explore complex material landscapes, complementing experimental research with the discovery of novel compounds. To enable these developments,…

Materials Science · Physics 2026-04-30 Holger-Dietrich Saßnick , Joshua Edzards , Timo Reents , Caterina Cocchi

Drug discovery remains time-consuming, labor-intensive, and expensive, often requiring years and substantial investment per drug candidate. Predicting compound-protein interactions (CPIs) is a critical component in this process, enabling…

Artificial Intelligence · Computer Science 2026-02-06 Zhe Wang , Zijing Liu , Chencheng Xu , Yuan Yao

Eisen is an open source python package making the implementation of deep learning methods easy. It is specifically tailored to medical image analysis and computer vision tasks, but its flexibility allows extension to any application. Eisen…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Frank Mancolo

Transient or permanent faults in hardware can render the output of Neural Networks (NN) incorrect without user-specific traces of the error, i.e. silent data errors (SDE). On the other hand, modern NNs also possess an inherent redundancy…

Artificial Intelligence · Computer Science 2023-10-31 Ralf Graafe , Qutub Syed Sha , Florian Geissler , Michael Paulitsch

Personalization customizes information access. The PIPE ("Personalization is Partial Evaluation") modeling methodology represents interaction with an information space as a program. The program is then specialized to a user's known…

Human-Computer Interaction · Computer Science 2007-05-23 Naren Ramakrishnan , Mary Beth Rosson , John M. Carroll

Explaining why the species lives at a particular location is important for understanding ecological systems and conserving biodiversity. However, existing ecological workflows are fragmented and often inaccessible to non-specialists. We…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Yutong Zhou , Masahiro Ryo

Motivation: Parameter estimation is a cornerstone of data-driven modeling in systems biology. Yet, constructing such problems in a reproducible and accessible manner remains challenging. The PEtab format has established itself as a powerful…

Quantitative Methods · Quantitative Biology 2025-11-17 Paul Jonas Jost , Frank T Bergmann , Daniel Weindl , Jan Hasenauer

Biophysics is a subject that is spread over many disciplines and transcends the skills and knowledge of the individual student. This makes it challenging both to teach and to learn. Educational materials are described to aid in teaching…

Physics Education · Physics 2015-06-15 J. M. Deutsch

Much of biology (and, indeed, all of science) is becoming increasingly computational. We tend to think of this in regards to algorithmic approaches and software tools, as well as increased computing power. There has also been a shift…

Computers and Society · Computer Science 2019-06-19 Anthony C Fletcher , Cameron Mura

IntLevPy provides a comprehensive description of the IntLevPy Package, a Python library designed for simulating and analyzing intermittent and L\'evy processes. The package includes functionalities for process simulation, including full…

Neural and Evolutionary Computing · Computer Science 2025-09-05 Shailendra Bhandari , Pedro Lencastre , Sergiy Denysov , Yurii Bystryk , Pedro G. Lind

Digital pathology plays a crucial role in the development of artificial intelligence in the medical field. The digital pathology platform can make the pathological resources digital and networked, and realize the permanent storage of visual…

Human-Computer Interaction · Computer Science 2021-11-11 Jialun Wu , Anyu Mao , Xinrui Bao , Haichuan Zhang , Zeyu Gao , Chunbao Wang , Tieliang Gong , Chen Li

We introduce GraSPy, a Python library devoted to statistical inference, machine learning, and visualization of random graphs and graph populations. This package provides flexible and easy-to-use algorithms for analyzing and understanding…

Social and Information Networks · Computer Science 2019-10-25 Jaewon Chung , Benjamin D. Pedigo , Eric W. Bridgeford , Bijan K. Varjavand , Hayden S. Helm , Joshua T. Vogelstein
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