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We present a dual-trap optical tweezers setup which directly measures forces using linear momentum conservation. The setup uses a counter-propagating geometry, which allows momentum measurement on each beam separately. The experimental…

Biological Physics · Physics 2013-07-04 Marco Ribezzi Crivellari , Josep M. Huguet , Felix Ritort

Advances in optical trapping design principles have led to tremendous progress in manipulating nanoparticles (NPs) with diverse functionalities in different environments using bulky systems. However, efficient control and manipulation of…

Biophysical force spectroscopy tools - for example optical tweezers, magnetic tweezers, atomic force microscopy, - have been used to study elastic, mechanical, conformational and dynamic properties of single biological specimens from single…

Biomolecules · Quantitative Biology 2016-06-09 Zhaokun Zhou , Mark C. Leake

Elasticity is a fundamental cellular property that is related to the anatomy, functionality and pathological state of cells and tissues. However, current techniques based on cell deformation, atomic force microscopy or Brillouin scattering…

In this work we consider the inverse problem of reconstructing the optical properties of a layered medium from an elastography measurement where optical coherence tomography is used as the imaging method. We hereby model the sample as a…

Numerical Analysis · Mathematics 2024-02-23 Peter Elbau , Leonidas Mindrinos , Leopold Veselka

In spite of the widespread use of optical tweezers as a quantitative tool to measure small forces, there exists no unambiguous and simple experimental method for either validating its theoretically predicted form or empirically…

Soft Condensed Matter · Physics 2013-01-25 Deepak Kumar , Shankar Ghosh , S. Bhattacharya

Photophoretic forces, several orders of magnitude stronger than radiation pressure, enable particle trapping at remarkably low optical intensities and have opened pathways to applications in aerosol science, free-space 3D volumetric…

Optics · Physics 2025-12-11 Anita Pahi , Kirty Ranjan Sahoo , Souvik Sil , Ayan Banerjee

Considering the nonlinear response of non-Newtonian fluids to the local shear exerted on the bulks of fluid, the initially quasi-uniform distribution of the particles might be subject to alteration as well, due to the unbalanced force…

Fluid Dynamics · Physics 2023-02-28 Kasra Amini , Gustaf Martensson , Outi Tammisola , Fredrik Lundell

We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse configuration to allow simultaneous mechanical measurement and…

Biomolecules · Quantitative Biology 2015-06-24 Zhaokun Zhou , Helen Miller , Adam J. M. Wollman , Mark C. Leake

Traction Force Microscopy (TFM) computes the forces exerted at the surface of an elastic material by measuring induced deformations in volume. It is used to determine the pattern of the adhesion forces exerted by cells or by cellular…

Biological Physics · Physics 2018-02-09 Stanislav Makarchuk , Nicolas Beyer , Christian Gaiddon , Wilfried Grange , Pascal Hébraud

Robot-assisted surgery has advantages compared to conventional laparoscopic procedures, e.g., precise movement of the surgical instruments, improved dexterity, and high-resolution visualization of the surgical field. However, mechanical…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Maximilian Neidhardt , Robin Mieling , Sarah Latus , Martin Fischer , Tobias Maurer , Alexander Schlaefer

Optical tweezers, formed by tightly focused propagating laser beams, offer the unique capability to trap and control microscopic particles over a broad size range. However, the diffraction inherent to propagating optical fields, limits the…

Optics · Physics 2025-07-29 Evgenii E. Narimanov

Acoustic tweezers can manipulate microscopic objects and cells independently of the optical, magnetic and electrical properties of the objects or their medium. However, because ultrasonic waves are attenuated within few millimeters,…

Fluid Dynamics · Physics 2022-03-29 Qing Wang , Shuhan Chen , Jia Zhou , Antoine Riaud

Arthur Ashkin was awarded the 2018 Nobel prize in physics for the invention of optical tweezers. Since the first publication in 1986 Optical Tweezers have been used as a tool to measure forces and rheological properties of microscopic…

Optics · Physics 2019-06-25 Antonio Alvaro Ranha Neves , Carlos Lenz Cesar

We propose an enantioselective scheme to sort homogeneous chiral particles using optical tweezers. For a certain range of material parameters, we show that a highly focused circularly-polarized laser beam traps particles of a specific…

Optics · Physics 2023-07-19 R. Ali , F. A. Pinheiro , R. S. Dutra , F. S. S. Rosa , P. A. Maia Neto

In terahertz (THz) photonics, there is an ongoing effort to develop thin, compact devices such as dielectric photonic crystal (PhC) slabs with desirable light matter interactions. However, previous works in THz PhC slabs are limited to…

Appropriate combinations of laser beams can be used to trap and manipulate small particles with "optical tweezers" as well as to induce significant "optical binding" forces between particles. These interaction forces are usually strongly…

Calibration of optically trapped particles in-vivo has been complicated given the frequency dependence and spatial inhomogeneity of the cytoplasmic viscosity, and the requirement of accurate knowledge of the medium refractive index.…

Biological Physics · Physics 2019-09-25 Rahul Vaippully , Vaibavi Ramanujan , Saumendra Bajpai , Basudev Roy

How far a particle moves along the optical axis in a holographic optical trap is not simply dictated by the programmed motion of the trap, but rather depends on an interplay of the trap's changing shape and the particle's material…

Soft Condensed Matter · Physics 2019-10-02 Michael J. O'Brien , David G. Grier

Photomechanical actuation is demonstrated in two coupled liquid crystal elastomer photomechanical optical devices (PODs) acting in series. The response function of an individual POD is characterized and used to predict the temporal response…