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Methods to effectively detect multi-locus genetic association are becoming increasingly relevant in the genetic dissection of complex trait in humans. Current approaches typically consider a limited number of hypotheses, most of which are…

Genomics · Quantitative Biology 2007-05-23 Zhong Li , Aris Floratos , David Wang , Andrea Califano

As a cross-topic of multi-view learning and multi-label classification, multi-view multi-label classification has gradually gained traction in recent years. The application of multi-view contrastive learning has further facilitated this…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Chengliang Liu , Jie Wen , Yong Xu , Bob Zhang , Liqiang Nie , Min Zhang

Depression and Attention Deficit Hyperactivity Disorder (ADHD) stand out as the common mental health challenges today. In affective computing, speech signals serve as effective biomarkers for mental disorder assessment. Current research,…

Audio and Speech Processing · Electrical Eng. & Systems 2025-03-05 Shuanglin Li , Siyang Song , Rajesh Nair , Syed Mohsen Naqvi

A fundamental approach in neuroscience research is to test hypotheses based on neuropsychological and behavioral measures, i.e., whether certain factors (e.g., related to life events) are associated with an outcome (e.g., depression). In…

Machine Learning · Computer Science 2022-08-01 Magdalini Paschali , Qingyu Zhao , Ehsan Adeli , Kilian M. Pohl

Multi-view data, that is matched sets of measurements on the same subjects, have become increasingly common with advances in multi-omics technology. Often, it is of interest to find associations between the views that are related to the…

Machine Learning · Statistics 2020-10-02 Yunfeng Zhang , Irina Gaynanova

The model interpretation is essential in many application scenarios and to build a classification model with a ease of model interpretation may provide useful information for further studies and improvement. It is common to encounter with a…

Machine Learning · Statistics 2019-01-07 Wan-Ping Nicole Chen , Yuan-chin Ivan Chang

Combined inference for heterogeneous high-dimensional data is critical in modern biology, where clinical and various kinds of molecular data may be available from a single study. Classical genetic association studies regress a single…

Applications · Statistics 2017-03-22 Hélène Ruffieux , Anthony C. Davison , Jörg Hager , Irina Irincheeva

Standard approaches for variable selection in linear models are not tailored to deal properly with high-dimensional and incomplete data. Currently, methods dedicated to high-dimensional data handle missing values by ad-hoc strategies, like…

Methodology · Statistics 2021-06-09 Avner Bar-Hen , Vincent Audigier

The lack of large labeled medical imaging datasets, along with significant inter-individual variability compared to clinically established disease classes, poses significant challenges in exploiting medical imaging information in a…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Matteo Ferrante , Tommaso Boccato , Simeon Spasov , Andrea Duggento , Nicola Toschi

Objective: Brain networks have gained increasing recognition as potential biomarkers in mental health studies, but there are limited approaches that can leverage complex brain networks for accurate classification. Our goal is to develop a…

Methodology · Statistics 2022-05-25 Jin Ming , Suprateek Kundu

Many statistical analyses involve the comparison of multiple data sets collected under different conditions in order to identify the difference in the underlying distributions. A common challenge in multi-sample comparison is the presence…

Methodology · Statistics 2016-04-07 Li Ma , Jacopo Soriano

High-dimensional phenotypes hold promise for richer findings in association studies, but testing of several phenotype traits aggravates the grand challenge of association studies, that of multiple testing. Several methods have recently been…

Methodology · Statistics 2013-05-14 Pekka Marttinen , Jussi Gillberg , Aki Havulinna , Jukka Corander , Samuel Kaski

Recent advancements in medicine have confirmed that brain disorders often comprise multiple subtypes of mechanisms, developmental trajectories, or severity levels. Such heterogeneity is often associated with demographic aspects (e.g., sex)…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Magdalini Paschali , Yu Hang Jiang , Spencer Siegel , Camila Gonzalez , Kilian M. Pohl , Akshay Chaudhari , Qingyu Zhao

Aortic stenosis (AS) is a degenerative valve condition that causes substantial morbidity and mortality. This condition is under-diagnosed and under-treated. In clinical practice, AS is diagnosed with expert review of transthoracic…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Zhe Huang , Benjamin S. Wessler , Michael C. Hughes

Anomaly detection (AD) plays a pivotal role in AI applications, e.g., in classification, and intrusion/threat detection in cybersecurity. However, most existing methods face challenges of heterogeneity amongst feature subsets posed by…

Artificial Intelligence · Computer Science 2025-01-15 Phai Vu Dinh , Diep N. Nguyen , Dinh Thai Hoang , Quang Uy Nguyen , Eryk Dutkiewicz

Clustering multivariate data is a pervasive task in many applied problems, particularly in social studies and life science. Model-based approaches to clustering rely on mixture models, where each mixture component corresponds to the kernel…

Methodology · Statistics 2026-01-22 Laura Ferrini , Federico Castelletti

Unsupervised person re-identification (Re-ID) is a promising and very challenging research problem in computer vision. Learning robust and discriminative features with unlabeled data is of central importance to Re-ID. Recently, more…

Computer Vision and Pattern Recognition · Computer Science 2022-05-12 Zheng Hu , Chuang Zhu , Gang He

Due to the costliness of labelled data in real-world applications, semi-supervised learning, underpinned by pseudo labelling, is an appealing solution. However, handling confusing samples is nontrivial: discarding valuable confusing samples…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Changrui Chen , Jungong Han , Kurt Debattista

Clustering is an essential technique for discovering patterns in data. The steady increase in amount and complexity of data over the years led to improvements and development of new clustering algorithms. However, algorithms that can…

Machine Learning · Statistics 2021-03-03 Shu Wang , Jonathan G. Yabes , Chung-Chou H. Chang

Visual Autoregressive (VAR) models have recently garnered significant attention for their innovative next-scale prediction paradigm, offering notable advantages in both inference efficiency and image quality compared to traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Tong Wang , Guanyu Yang , Nian Liu , Kai Wang , Yaxing Wang , Abdelrahman M Shaker , Salman Khan , Fahad Shahbaz Khan , Senmao Li